Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Marzia Cirri"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1351 (2024)
Background: Propranolol, largely prescribed as an antihypertensive and antiarrhythmic drug in pediatrics, is characterized by a bitter taste and an astringent aftertaste. Currently, the therapy requires crushing of tablets for adults and their disper
Externí odkaz:
https://doaj.org/article/b99206718ab14b3e929cd9e6d0e9b3bf
Autor:
Francesca Maestrelli, Marzia Cirri, Natascia Mennini, Silvia Fiani, Beatrice Stoppacciaro, Paola Mura
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 633 (2024)
New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the main reason behind its poor/variable oral bioavailability. Phase-solubility studies, performed usi
Externí odkaz:
https://doaj.org/article/e417fe18ca5b48a58231e1c77318c1e1
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2217 (2023)
Propranolol (PPN) is widely used in children to treat various cardiovascular diseases. The availability of a suitable PPN solution should avoid recourse to extemporaneous preparations of unknown/limited stability, as commonly made in hospital pharmac
Externí odkaz:
https://doaj.org/article/9ea23bcfc2ec4c569a556ae37a3473c0
Autor:
Giulia Nerli, Lídia M. D. Gonçalves, Marzia Cirri, António J. Almeida, Francesca Maestrelli, Natascia Mennini, Paola A. Mura
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1305 (2023)
There is a serious need of pediatric drug formulations, whose lack causes the frequent use of extemporaneous preparations obtained from adult dosage forms, with consequent safety and quality risks. Oral solutions are the best choice for pediatric pat
Externí odkaz:
https://doaj.org/article/85b3c7ca18284c59ab484ea8e044bba2
Autor:
Nastassja Burrini, Mario D’Ambrosio, Matteo Gentili, Roberta Giaquinto, Veronica Settimelli, Cristina Luceri, Marzia Cirri, Oscar Francesconi
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 235 (2023)
Niosomes are a potential tool for the development of active targeted drug delivery systems (DDS) for cancer therapy because of their excellent behaviour in encapsulating antitumorals and the possibility to easily functionalise their surface with targ
Externí odkaz:
https://doaj.org/article/e81dd2d85a5b463ba22568c4524020d8
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2567 (2022)
Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications. Cyclodextrins (CDs) have been utilised to enhance the nanogels’ loading ability towards p
Externí odkaz:
https://doaj.org/article/47bd99645ba643b6b4a30f32e63ad74d
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 335 (2022)
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects. Since joining the p
Externí odkaz:
https://doaj.org/article/5c887f89978f45aca8b4c25705d36421
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 284 (2022)
Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence. Different FFA batches, obtained by different suppliers, showed different powder charact
Externí odkaz:
https://doaj.org/article/ae158a51d9534d17b93364866b6420c3
Autor:
Marzia Cirri, Lavinia Maestrini, Francesca Maestrelli, Natascia Mennini, Paola Mura, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1910-1921 (2018)
The hydrochlorothiazide (HCT) low solubility and permeability give rise to limited and variable bioavailability; its low stability makes it difficult to develop stable aqueous liquid formulations; its low dose makes the achievement of a homogeneous d
Externí odkaz:
https://doaj.org/article/b3cef52e65084eed9725b8d03ede50e8
Autor:
Andrea Angeli, Emanuela Berrino, Simone Carradori, Claudiu T. Supuran, Marzia Cirri, Fabrizio Carta, Gabriele Costantino
Publikováno v:
Molecules, Vol 26, Iss 23, p 7331 (2021)
After being rather neglected as a research field in the past, carbonic anhydrase activators (CAAs) were undoubtedly demonstrated to be useful in diverse pharmaceutical and industrial applications. They also improved the knowledge of the requirements
Externí odkaz:
https://doaj.org/article/1481f0df51d744b79e35521988da624a