Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Marzena Walkiewicz"'
Autor:
Silvia Velasco, Maria Giovanna Garone, Vallari Sawant, Maria Rosaria Nucera, Anna Leichter, Marzena Walkiewicz
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S36- (2023)
Externí odkaz:
https://doaj.org/article/dbe7e6874d16480d89c1566d8dd3ee13
Autor:
Surein Arulananda, Megan O’Brien, Marco Evangelista, Laura J. Jenkins, Ashleigh R. Poh, Marzena Walkiewicz, Trishe Leong, John M. Mariadason, Jonathan Cebon, Srividya B. Balachander, Justin R. Cidado, Erinna F. Lee, Thomas John, Walter D. Fairlie
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Malignant pleural mesothelioma (MPM) is an aggressive cancer with treatment limited to Cisplatin and Pemetrexed chemotherapy. Recently, we showed that drugs targeting the BCL-2-regulated apoptosis pathway could kill MPM cell lines in vitro,
Externí odkaz:
https://doaj.org/article/ad883c64d8a746e29bfa7c2330196e64
Autor:
Guy Helman, Bryan R. Lajoie, Joanna Crawford, Asako Takanohashi, Marzena Walkiewicz, Egor Dolzhenko, Andrew M. Gross, Vladimir G. Gainullin, Stephen J. Bent, Emma M. Jenkinson, Sacha Ferdinandusse, Hans R. Waterham, Imen Dorboz, Enrico Bertini, Noriko Miyake, Nicole I. Wolf, Truus E. M. Abbink, Susan M. Kirwin, Christina M. Tan, Grace M. Hobson, Long Guo, Shiro Ikegawa, Amy Pizzino, Johanna L. Schmidt, Genevieve Bernard, Raphael Schiffmann, Marjo S. van derKnaap, Cas Simons, Ryan J. Taft, Adeline Vanderver
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 1, Pp 144-152 (2020)
Abstract Genetic white matter disorders have heterogeneous etiologies and overlapping clinical presentations. We performed a study of the diagnostic efficacy of genome sequencing in 41 unsolved cases with prior exome sequencing, resolving an addition
Externí odkaz:
https://doaj.org/article/b313ae0552894ab4b545c7fc6b8eee71
Autor:
Surein Arulananda, Megan O’Brien, Marco Evangelista, Tiffany J. Harris, Nikita S. Steinohrt, Laura J. Jenkins, Marzena Walkiewicz, Robert J. J. O’Donoghue, Ashleigh R. Poh, Bibhusal Thapa, David S. Williams, Trishe Leong, John M. Mariadason, Xia Li, Jonathan Cebon, Erinna F. Lee, Thomas John, W. Douglas Fairlie
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/768c48b448e544079fe397dafe8d4bf3
Autor:
Malaka Ameratunga, Khashayar Asadi, Xihui Lin, Marzena Walkiewicz, Carmel Murone, Simon Knight, Paul Mitchell, Paul Boutros, Thomas John
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153954 (2016)
INTRODUCTION:Immune checkpoint inhibition has shifted treatment paradigms in non-small cell lung cancer (NSCLC). Conflicting results have been reported regarding the immune infiltrate and programmed death-ligand 1 (PD-L1) as a prognostic marker. We c
Externí odkaz:
https://doaj.org/article/8ded8d565695400a8df2226657f469f4
Autor:
Thomas John, Maud H W Starmans, Yao-Tseng Chen, Prudence A Russell, Stephen A Barnett, Shane C White, Paul L Mitchell, Marzena Walkiewicz, Arun Azad, Philippe Lambin, Ming-Sound Tsao, Siddhartha Deb, Nasser Altorki, Gavin Wright, Simon Knight, Paul C Boutros, Jonathan S Cebon
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67876 (2013)
BACKGROUND: Cancer-Testis Antigens (CTAs) are immunogenic proteins that are poor prognostic markers in non-small cell lung cancer (NSCLC). We investigated expression of CTAs in NSCLC and their association with response to chemotherapy, genetic mutati
Externí odkaz:
https://doaj.org/article/6a531e39d5c94c5f9091c1d48f459ca3
Autor:
John M. Mariadason, Paul C. Boutros, Gavin M. Wright, Mun Sem Liew, Thomas John, Aparna Jayachandran, Anderly C. Chueh, Maud H.W. Starmans, Stephen Barnett, Prudence A. Russell, Marzena Walkiewicz
Publikováno v:
Oncotarget
Oncotarget, vol 8, iss 43
Oncotarget, vol 8, iss 43
Cancer-Testis antigens (CTA) are immunogenic molecules with normal tissue expression restricted to testes but with aberrant expression in up to 30% of non-small cell lung cancers (NSCLCs). Regulation of CTA expression is mediated in part through prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3c9cbe6ee2025e8af7e3a77b76257a
Autor:
Edward K Murrell, Vihandha O. Wickramasinghe, Sean Massey, Russell Gear, Susan M. White, Lyndon Gallacher, John Christodoulou, Lynn Pais, Kate Pope, Cas Simons, Kirsty Carey, Paul J. Lockhart, Katrina M. Bell, Andrew J. Kornberg, Nicole J Van Bergen, Marzena Walkiewicz
Publikováno v:
Hum Mol Genet
The nuclear pore complex (NPC) is a multi-protein complex that regulates the trafficking of macromolecules between the nucleus and cytoplasm. Genetic variants in components of the NPC have been shown to cause a range of neurological disorders, includ
Autor:
Laura J. Jenkins, Ashleigh R Poh, W.D. Fairlie, Marco Evangelista, Erinna F. Lee, Srividya B. Balachander, John M. Mariadason, Trishe Leong, Megan O'Brien, Jonathan Cebon, Surein Arulananda, Justin Cidado, Thomas John, Marzena Walkiewicz
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Cell Death Discovery
Cell Death Discovery
Malignant pleural mesothelioma (MPM) is an aggressive cancer with treatment limited to Cisplatin and Pemetrexed chemotherapy. Recently, we showed that drugs targeting the BCL-2-regulated apoptosis pathway could kill MPM cell lines in vitro, and contr
Autor:
Sagun Parakh, Thomas John, Marzena Walkiewicz, Khashayer Asadi, Andrew M. Scott, Puey Ling Chia, Val Gebski, Carmel Murone, Prudence A. Russell, Fiona Scott, Bibhusal Thapa, Hui K Gan, Zhanqi Liu
Publikováno v:
Lung Cancer. 153:35-41
Aim Conformational forms of the epidermal growth factor receptor (EGFR) are pro‐tumorigenic. The prevalence and impact of conformational forms of EGFR in malignant mesothelioma (MM) is unknown. We investigated expression of EGFR and conformational