Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marzena Rzadkowska"'
Autor:
Marcin Sysa, Magdalena Iwan, Marzena Rzadkowska, Dariusz Matosiuk, Ewelina Humeniuk, Agnieszka Korga, Jarosław Dudka, Elżbieta Szacoń, Marta Ostrowska
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 33, Iss 1, Pp 1-5 (2020)
Doxorubicin cardiotoxicity is caused by various mechanisms, most importantly by oxidative stress originating in the mitochondria. Tirapazamine is a hypoxia-activated anticancer experimental drug. Both drugs in normoxia conditions undergo univalent re
Autor:
Ewa Poleszak, Katarzyna Swiader, Marzena Rzadkowska, Regina Kasperek, Maria Zuń, Dorota Dwornicka, Katarzyna Wojciechowska
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 27, Iss 4, Pp 213-216 (2014)
In this study, the stability of 10% hydrogen peroxide aqueous and non-aqueous solutions with the addition of 6% (w/w) of urea was evaluated. The solutions were stored at 20°C, 30°C and 40°C, and the decomposition of hydrogen peroxide proceeded acc
Autor:
Elżbieta Szacoń, Agnieszka A. Kaczor, Ewa Kędzierska, Sylwia Fidecka, Dariusz Matosiuk, Marzena Rzadkowska
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 10(5)
Pain management is an important medical problem with social and economic consequences. Opioid receptors are among the most important molecular targets involved in antinociception. We have previously reported several series of antinociceptive compound
Publikováno v:
Acta poloniae pharmaceutica. 69(6)
In the reaction of ethyl N-(1-arylimidazolidine-2-ylidene) carbamic acid ester with 4-chlorobenzylamine new derivatives of 1-(1-arylimidazolidine-2-ylidene)-3-arylurea (I-VI) were obtained. Cyclic derivatives of dihydroimidazo[l ,2-a][1,3,5]trizines
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 27, Iss 1, Pp 8-9 (2014)
In the recent years at the Department of Synthesis and Technology of Drugs, a number of fused derivatives of triazepine has been synthesized [11,13]. The synthetic derivatives of triazepine form various and important group of medicines. In the search
Autor:
Henri Kivelä, Dariusz Matosiuk, Elżbieta Szacoń, Marzena Rzadkowska, Olli Martiskainen, Kalevi Pihlaja
Publikováno v:
Rapid communications in mass spectrometry : RCM. 21(23)
The electron ionization mass spectra of the 1-phenyl-, 1-benzyl- and 6-benzyl-1-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5,7(1H,6H)-dione derivatives were recorded at 70 eV to find out the effects of substituents on their fragmentations. Fragmentat
Publikováno v:
Rapid Communications in Mass Spectrometry. 11:1043-1045
Fragmentation pathways of the title compounds were studied using accurate mass measurements, collision-induced dissociation and mass-analysed icon kinetic energy spectrometry. Primary fragmentation of M+. ions involves the sulphamide bond cleavage to
Autor:
Elżbieta Szacoń, Marzena Rządkowska, Agnieszka A. Kaczor, Ewa Kędzierska, Sylwia Fidecka, Dariusz Matosiuk
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 3821-3840 (2015)
A series of 10 novel urea derivatives has been synthesized and evaluated for their central nervous system activity. Compounds 3a–3h were prepared in the reaction between the respective 1-alkyl-4-aryl-4,5-dihydro-1H-imidazol-2-amines 1a and 1b and a
Externí odkaz:
https://doaj.org/article/0e7c10ca5d56400d856c553ca0ba1b3c
Autor:
Elżbieta Szacoń, Marzena Rządkowska, Agnieszka A. Kaczor, Ewa Kędzierska, Jolanta Orzelska-Górka, Sylwia Fidecka, Dariusz Matosiuk
Publikováno v:
Molecules, Vol 21, Iss 5, p 582 (2016)
Novel 1-(1,4-alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted urea derivatives have been synthesized and evaluated for their central nervous system activity. Compounds 3a–m were prepared in the reaction between the respective 1-alkyl-4-
Externí odkaz:
https://doaj.org/article/fe94e3266f4a4d50b7317becb7137c4c
Autor:
Waldemar Wysocki, Dariusz Matosiuk, Marzena Rządkowska, Zbigniew Karczmarzyk, Zofia Urbańczyk-Lipkowska, Przemysław Kalicki
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 11, Pp o2742-o2743 (2010)
The title compound, C19H15Cl2N3O2, was obtained by a one-step cyclocondensation of 2-amino-1-(4-chlorophenyl)imidazoline with diethyl (2-chlorobenzyl)malonate under basic conditions. In the crystalline state, the molecule exists as the 7-hydroxy-5-ox
Externí odkaz:
https://doaj.org/article/cef0527d8f7743e398eb6cb69bfcd3bd