Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Marzanna Cechowska-Pasko"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1089 (2024)
Proteasomes play an important role in the physiology of cancer cells, and inhibition of their activity may be used as a promising therapeutic strategy against glioblastoma (GBM). Although certain proteasome inhibitors (PIs) have been approved for the
Externí odkaz:
https://doaj.org/article/08e816ac894f49678d73dd7628fa9ad1
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 315 (2024)
Malignant melanoma—a tumor originating from melanocytes—is characterized by dynamic growth and frequent metastases in the early stage of development. Current therapy methods are still insufficient, and there is a need to search for new ways of tr
Externí odkaz:
https://doaj.org/article/5d25476a1c8a4ea590ef0fd7adcbd636
Autor:
Agata Jabłońska-Trypuć, Urszula Wydro, Elżbieta Wołejko, Monika Kalinowska, Grzegorz Świderski, Rafał Krętowski, Monika Naumowicz, Paweł Kondzior, Marzanna Cechowska-Pasko, Włodzimierz Lewandowski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5655 (2024)
Mesotrione, as a widely used herbicide, is present in the environment in detectable amounts, causing serious damage. Here, we aimed to investigate the effect of mesotrione on Caco-2 cells and the possibility of its toxicity mitigation by cichoric aci
Externí odkaz:
https://doaj.org/article/da76f258595e48e09da81532e3724eb5
Autor:
Rafał Krętowski, Beata Szynaka, Agata Jabłońska-Trypuć, Anna Kiełtyka-Dadasiewicz, Marzanna Cechowska-Pasko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5436 (2024)
Reduced graphene oxide (rGO) and a proteasome inhibitor (MG-132) are some of the most commonly used compounds in various biomedical applications. However, the mechanisms of rGO- and MG-132-induced cytotoxicity remain unclear. The aim of this study wa
Externí odkaz:
https://doaj.org/article/1387dbbd14fb41fc824563e46fbe658b
Autor:
Agata Jabłońska-Trypuć, Urszula Wydro, Elżbieta Wołejko, Marcin Makuła, Rafał Krętowski, Monika Naumowicz, Gabriela Sokołowska, Lluis Serra-Majem, Marzanna Cechowska-Pasko, Bożena Łozowicka, Piotr Kaczyński, Józefa Wiater
Publikováno v:
Molecules, Vol 28, Iss 21, p 7437 (2023)
An increasing level of pesticide exposition is being observed as a result of the consumption of large amounts of fruits, vegetables and grain products, which are key components of the vegetarian diet. Fungicides have been classified as endocrine-disr
Externí odkaz:
https://doaj.org/article/041d768bf15c4321be0f7b30e09842db
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2037 (2023)
Breast cancer is one of the most common cancers in women. Silica nanoparticles (SiNPs) belong to the group of often-used nanoparticles in biomedical applications. The mechanisms of the cytotoxicity, apoptosis, and oxidative stress induced by the 5–
Externí odkaz:
https://doaj.org/article/0c58ac8e73af4045805671cbc31942f9
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11082 (2022)
Cellular senescence process results in stable cell cycle arrest, which prevents cell proliferation. It can be induced by a variety of stimuli including metabolic stress, DNA damage, telomeres shortening, and oncogenes activation. Senescence is genera
Externí odkaz:
https://doaj.org/article/4907d848e2da491396801040120a2335
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9285 (2022)
Reduced graphene oxide (rGO) has already been reported as a potential cytostatic agent in various cancers. However, the mechanisms underlying rGO’s cytotoxicity are still insufficiently understood. Thus, the aim of the study was to investigate the
Externí odkaz:
https://doaj.org/article/a9e5b331e5ef4607a3bdbeccef975171
Autor:
Magdalena Kusaczuk, Rafał Krętowski, Monika Naumowicz, Anna Stypułkowska, Marzanna Cechowska-Pasko
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1345 (2022)
A growing body of evidence indicates that dietary polyphenols show protective effects against various cancers. However, little is known yet about their activity in brain tumors. Here we investigated the interaction of dietary flavonoid quercetin (QCT
Externí odkaz:
https://doaj.org/article/85db5dec1d404ecf9bdf28587626a760
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12593 (2021)
Breast cancer is the most common cancer diagnosed in women, however traditional therapies have several side effects. This has led to an urgent need to explore novel drug approaches to treatment strategies such as graphene-based nanomaterials such as
Externí odkaz:
https://doaj.org/article/221405000f664bd182c15b9e8d1e0b8e