Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maryvonne Jezequel-Cuer"'
Publikováno v:
Liver. 12:140-146
The hyperfucosylation of a number of glycoconjugates observed in liver diseases involves the action of several specific fucosyltransferases (F.T.) notably responsible for synthesizing histo-blood group antigens. We determined the activities of alpha
Autor:
Maryvonne Jezequel-Cuer, Sophie Gayno, Geneviève Durand, Nathalie Seta, Serge Erlinger, Marie-Laure Toueg
Publikováno v:
Journal of Hepatology. 26:265-271
alpha-Fetoprotein is a useful diagnostic marker in hepatocellular carcinoma, during which its serum level increases and its glycan structure is hyperfucosylated. Normally-expressed glycoproteins (alpha 1-antitrypsin and transferrin) are also hyperfuc
Publikováno v:
Biochimica et biophysica acta. 1157(3)
A purified alpha 1-3 fucosyltransferase (alpha 1-3 FT) was recovered in the Golgi fraction of isolated hepatocytes from normal human liver tissue. The efficiency of purification was controlled by measurement of fucose transfer to asialotransferrin (f