Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maryssa Beasley"'
Autor:
Alyssa R. Stonebraker, Maryssa Beasley, Sophia Massinople, Michelle Wunder, Peng Li, Stephen J. Valentine, Justin Legleiter
Publikováno v:
Protein Science. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d720c81a60119c47a6db1490183df79
https://doi.org/10.1002/pro.4642
https://doi.org/10.1002/pro.4642
Autor:
Maryssa Beasley, Nicolas Frazee, Sharon Groover, Stephen J. Valentine, Blake Mertz, Justin Legleiter
Publikováno v:
The Journal of Physical Chemistry B. 126:3067-3081
Huntington's disease is a neurodegenerative disorder caused by an expanded polyglutamine (polyQ) domain within the huntingtin protein (htt) that initiates toxic protein aggregation. Htt directly interacts with membranes, influencing aggregation and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125a0fecd360000f9d6992e5c68b92ca
https://doi.org/10.1021/acs.jpcb.1c10254
https://doi.org/10.1021/acs.jpcb.1c10254
Publikováno v:
Soft Matter.
Nature employs protein aggregates when strong materials are needed to adhere surfaces in extreme environments, allowing organisms to survive conditions ranging from harsh intertidal coasts to open oceans. Amyloids and...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07d711134e38a5e1dfd09b20fe1adeee
https://doi.org/10.1039/d3sm00342f
https://doi.org/10.1039/d3sm00342f
Autor:
Ahmad Kiani Karanji, James R. Arndt, Mahdiar Khakinejad, Maxmore Chaibva, Maryssa Beasley, Samaneh Ghassabi Kondalaji, Stephen J. Valentine, Justin Legleiter, Olivia Sarver
Publikováno v:
Biochemistry
Huntington’s disease (HD) is a genetic neurodegenerative disorder characterized by the formation of amyloid fibrils of the huntingtin protein (htt). The seventeen-residue N-terminal region of htt (Nt(17)) has been implicated in formation of early-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a754ebce5fc587126ee69d732addd79
https://doi.org/10.1021/acs.biochem.9b00689
https://doi.org/10.1021/acs.biochem.9b00689
Autor:
Caleb K. Fan, Justin Legleiter, Sharon E. Groover, Maryssa Beasley, Katelyn Taylor, Adewale Adegbuyiro, Breanna L. Hodges, Chathuranga Siriwardhana, Alyssa R. Stonebraker
Publikováno v:
Colloids Surf B Biointerfaces
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine (polyQ) domain within the first exon of the huntingtin protein (htt). PolyQ expansion directly invokes the formation of a heterogenous mixture of tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7502d71cd85bf5c0322a2b25b82721d
https://europepmc.org/articles/PMC8429182/
https://europepmc.org/articles/PMC8429182/
Publikováno v:
Biophysical Journal. 121:544a-545a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38c777e495984c2222edb92f2121d57
https://doi.org/10.1016/j.bpj.2021.11.2870
https://doi.org/10.1016/j.bpj.2021.11.2870
Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems
Publikováno v:
Biochemistry. 59(49)
Huntington's disease (HD) is a neurodegenerative disorder caused by the abnormal expansion of a polyglutamine (polyQ) tract in the first exon of the htt protein (htt). PolyQ expansion triggers the aggregation of htt into a variety of structures, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745b926803a6dd8edd764d077b3d3486
https://pubmed.ncbi.nlm.nih.gov/33256402
https://pubmed.ncbi.nlm.nih.gov/33256402
Publikováno v:
Biochim Biophys Acta Biomembr
Huntington's Disease is a fatal neurodegenerative disorder caused by expansion of a glutamine repeat region (polyQ) beyond a critical threshold within exon1 of the huntingtin protein (htt). As a consequence of polyQ expansion, htt associates into a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dfa28dc107a98aa92cce91d3801445
https://pubmed.ncbi.nlm.nih.gov/33130095
https://pubmed.ncbi.nlm.nih.gov/33130095
Publikováno v:
Analytical biochemistry. 609
Mixed polydiacetylene (PDA) lipid vesicles mimic cell membranes and exhibit a colorimetric response induced by mechanical stress, which can be used to determine the affinity of proteins or molecules for lipid membranes. Due to a simple spectroscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4496d469e1e02a59e99bc0b2d478de2b
https://pubmed.ncbi.nlm.nih.gov/32846147
https://pubmed.ncbi.nlm.nih.gov/32846147