Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maryse Schmoetten"'
Autor:
Mohaned Benzarti, Laura Neises, Anais Oudin, Christina Krötz, Elodie Viry, Ernesto Gargiulo, Coralie Pulido, Maryse Schmoetten, Vitaly Pozdeev, Nadia I. Lorenz, Michael W. Ronellenfitsch, David Sumpton, Marc Warmoes, Christian Jaeger, Antoine Lesur, Björn Becker, Etienne Moussay, Jerome Paggetti, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113868- (2024)
Summary: Modeling tumor metabolism in vitro remains challenging. Here, we used galactose as an in vitro tool compound to mimic glycolytic limitation. In contrast to the established idea that high glycolytic flux reduces pyruvate kinase isozyme M2 (PK
Externí odkaz:
https://doaj.org/article/70167f7828434ce29cdc23c2703e97a7
Autor:
Nicole Kiweler, Catherine Delbrouck, Vitaly I. Pozdeev, Laura Neises, Leticia Soriano-Baguet, Kim Eiden, Feng Xian, Mohaned Benzarti, Lara Haase, Eric Koncina, Maryse Schmoetten, Christian Jaeger, Muhammad Zaeem Noman, Alexei Vazquez, Bassam Janji, Gunnar Dittmar, Dirk Brenner, Elisabeth Letellier, Johannes Meiser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Chemotherapeutic antifolates, such as methotrexate (MTX), impair cancer cell proliferation by inhibiting nucleotide synthesis. Here, the authors show that MTX sustains an autarkic mitochondrial one-carbon metabolism leading to serine synthesis to pro
Externí odkaz:
https://doaj.org/article/1b8b8042e550427e9245dff67e377dae
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
Supplementary Figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac555aa6d9d63833368748b3be0a555
https://doi.org/10.1158/2326-6066.22543494
https://doi.org/10.1158/2326-6066.22543494
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
IL1β is a central mediator of inflammation. Secretion of IL1β typically requires proteolytic maturation by the inflammasome and formation of membrane pores by gasdermin D (GSDMD). Emerging evidence suggests an important role for IL1β in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17834bb72b19f02c483a544d32dc5d61
https://doi.org/10.1158/2326-6066.c.6550290
https://doi.org/10.1158/2326-6066.c.6550290
Autor:
Mohaned Benzarti, Anais Oudin, Elodie Viry, Ernesto Gargiulo, Maryse Schmoetten, Laura Neises, Coralie Pulido, Nadia I. Lorenz, Michael W. Ronellenfitsch, David Sumpton, Marc Warmoes, Christian Jaeger, Antoine Lesur, Etienne Moussay, Jerome Paggetti, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser
Throughout the metastatic cascade, cancer cells are faced with harsh metabolic environments and nutritional stresses which apply selection pressure leaving only the most metabolically resilient cells to survive and form metastases. Metabolic characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a522bab3a28454fca112d3efdad6bfe
https://doi.org/10.1101/2023.01.23.525168
https://doi.org/10.1101/2023.01.23.525168
Autor:
Dominik Ternes, Mina Tsenkova, Vitaly Igorevich Pozdeev, Marianne Meyers, Eric Koncina, Sura Atatri, Martine Schmitz, Jessica Karta, Maryse Schmoetten, Almut Heinken, Fabien Rodriguez, Catherine Delbrouck, Anthoula Gaigneaux, Aurelien Ginolhac, Tam Thuy Dan Nguyen, Lea Grandmougin, Audrey Frachet-Bour, Camille Martin-Gallausiaux, Maria Pacheco, Lorie Neuberger-Castillo, Paulo Miranda, Nikolaus Zuegel, Jean-Yves Ferrand, Manon Gantenbein, Thomas Sauter, Daniel Joseph Slade, Ines Thiele, Johannes Meiser, Serge Haan, Paul Wilmes, Elisabeth Letellier
Different gut bacteria have been shown to promote colorectal cancer (CRC) progression. The authors identify formate as an oncometabolite derived from Fusobacterium nucleatum, which promotes CRC formation by increasing cancer stemness. The gut microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824aa6c2031123be3851f8518a587dce
https://hdl.handle.net/10919/111081
https://hdl.handle.net/10919/111081
Autor:
Laura Neises, Christian Jaeger, Catherine Delbrouck, Nicole Kiweler, Mohaned Benzarti, Lara Haase, Gunnar Dittmar, Bassam Janji, Alexei Vazquez, Dirk Brenner, Feng Xiang, Johannes Meiser, Maryse Schmoetten, Muhammad Zaeem Noman, Leticia Soriano-Baguet, Elisabeth Letellier, Vitaly I. Pozdeev
Progression of primary cancer to metastatic disease is the most common cause of death in cancer patients with minimal treatment options available. Canonical drugs target mainly the proliferative capacity of cancer cells, which often leaves slow-proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43667082eddce4e1001ceccdbd868441
https://doi.org/10.21203/rs.3.rs-639444/v1
https://doi.org/10.21203/rs.3.rs-639444/v1
Autor:
Nicole Kiweler, Catherine Delbrouck, Vitaly I. Pozdeev, Laura Neises, Leticia Soriano-Baguet, Kim Eiden, Feng Xian, Mohaned Benzarti, Lara Haase, Eric Koncina, Maryse Schmoetten, Christian Jaeger, Muhammad Zaeem Noman, Alexei Vazquez, Bassam Janji, Gunnar Dittmar, Dirk Brenner, Elisabeth Letellier, Johannes Meiser
Progression of primary cancer to metastatic disease is the most common cause of death in cancer patients with minimal treatment options available. Canonical drugs target mainly the proliferative capacity of cancer cells, which often leaves slow-proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8c2086ea73b36639fb06fc9e2f90da
https://doi.org/10.1101/2021.05.27.445928
https://doi.org/10.1101/2021.05.27.445928
Autor:
Mate Kiss, Geert Raes, Maryse Schmoetten, Helena Van Damme, Andy Wullaert, Jiri Keirsse, Mohamed Lamkanfi, Yvon Elkrim, Pauline M. R. Bardet, Junbin Qian, Aleksandar Murgaski, Louis Boon, Diether Lambrechts, Samantha Pretto, Alain Beschin, Geert van Loo, Massimiliano Mazzone, Manuel Ehling, Jo A. Van Ginderachter, Damya Laoui, Sana M. Arnouk, Evangelia Bolli, Ayla Debraekeleer, Amelie Fossoul, Els Lebegge, Jan Brughmans, Lieselotte Vande Walle, Pedro Henrique Viana Saavedra
IL1β is a central mediator of inflammation. Secretion of IL1β typically requires proteolytic maturation by the inflammasome and formation of membrane pores by gasdermin D (GSDMD). Emerging evidence suggests an important role for IL1β in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecbd8e2b94bd021c47f81139d016a57
https://doi.org/10.1158/2326-6066.cir-20-0431
https://doi.org/10.1158/2326-6066.cir-20-0431