Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Maryse Lebrun"'
Autor:
Rania Najm, Maguy Hamie, Laurence Berry-Sterkers, Maryse Lebrun, Hiba El Hajj, Mauld H. Lamarque
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Toxoplasma gondii is a single-celled parasitic eukaryote that evolved to successfully propagate in any nucleated cell. As with any other eukaryote, its life cycle is regulated by signaling pathways controlled by kinases and phosphatases. T.
Externí odkaz:
https://doaj.org/article/fcc3c339335f47d8b3ad117f03336246
Autor:
Shrawan Kumar Mageswaran, Amandine Guérin, Liam M. Theveny, William David Chen, Matthew Martinez, Maryse Lebrun, Boris Striepen, Yi-Wei Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including lum
Externí odkaz:
https://doaj.org/article/65277b58fe3c478dae8f5b0f288611d4
Autor:
Aditya S. Paul, Alexandra Miliu, Joao A. Paulo, Jonathan M. Goldberg, Arianna M. Bonilla, Laurence Berry, Marie Seveno, Catherine Braun-Breton, Aziz L. Kosber, Brendan Elsworth, Jose S. N. Arriola, Maryse Lebrun, Steven P. Gygi, Mauld H. Lamarque, Manoj T. Duraisingh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental sig
Externí odkaz:
https://doaj.org/article/7d2715bdc7484f8c88c035dcb70a2f3f
Autor:
Catherine Suarez, Gaëlle Lentini, Raghavendran Ramaswamy, Marjorie Maynadier, Eleonora Aquilini, Laurence Berry-Sterkers, Michael Cipriano, Allan L. Chen, Peter Bradley, Boris Striepen, Martin J. Boulanger, Maryse Lebrun
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Plasmodium and Toxoplasma parasites rely on rhoptry exocytosis for invasion, but the underlying mechanism is not known. Here, Suarez et al. characterize rhoptry apical surface proteins (RASP) that localize to the rhoptry cap and bind charged lipids,
Externí odkaz:
https://doaj.org/article/5d7eb981430d428a86981e90c449cc6b
Autor:
Maguy Hamie, Nadim Tawil, Rana El Hajj, Rania Najm, Sara Moodad, Rita Hleihel, Martin Karam, Sana El Sayyed, Sébastien Besteiro, Marwan El-Sabban, Jean-Francois Dubremetz, Maryse Lebrun, Hiba El Hajj
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Toxoplasmosis is a prevalent parasitic disease caused by Toxoplasma gondii (T. gondii). Under the control of the host immune system, T. gondii persists as latent bradyzoite cysts. Immunosuppression leads to their reactivation, a potentially life-thre
Externí odkaz:
https://doaj.org/article/174776ee7cff46f292d2181ca2488365
Autor:
Sarah K Wilson, Justine Heckendorn, Bruno Martorelli Di Genova, Lindsey L Koch, Peggy J Rooney, Naomi Morrissette, Maryse Lebrun, Laura J Knoll
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008650 (2020)
Toxoplasma gondii is an obligate intracellular parasite that can invade any nucleated cell of any warm-blooded animal. In a previous screen to identify virulence determinants, disruption of gene TgME49_305140 generated a T. gondii mutant that could n
Externí odkaz:
https://doaj.org/article/5169075d6e3d4e24bb076850e4da42df
Autor:
Shrawan Kumar Mageswaran, Amandine Guérin, Liam M. Theveny, William David Chen, Matthew Martinez, Maryse Lebrun, Boris Striepen, Yi-Wei Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/f75802a3d0e34df181b0b06506720838
Publikováno v:
Annual Review of Microbiology. 76:619-640
Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells. Invasion is a conserved process that relies on the timely and spatially controlled exocytosis of unique specialized secretory organelles termed micronemes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a5192da665c5c21f53d4dd9f35201f
https://doi.org/10.1146/annurev-micro-041320-021425
https://doi.org/10.1146/annurev-micro-041320-021425
Autor:
Maguy Hamie, Nadim Tawil, Lea Maalouf, Rana El Hajj, Rania Najm, Rita Hleihel, Martin Karam, Layal Nasr, Sébastien Beistero, Jean-Francois Dubremetz, Maryse Lebrun, Hiba El Hajj
Publikováno v:
Journal of Infection and Public Health, Vol 13, Iss 12, Pp 2116-2117 (2020)
Externí odkaz:
https://doaj.org/article/20f9ba6c883d44029703a5f97911e813
Autor:
Rania Najm, Margarida T. Grilo Ruivo, Diana Marcela Penarete-Vargas, Maguy Hamie, Thomas Mouveaux, Mathieu Gissot, Martin J. Boulanger, Hiba El Hajj, Maryse Lebrun
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Toxoplasmosis is a neglected parasitic disease necessitating public health control. Host cell invasion by Toxoplasma occurs at different stages of the parasite’s life cycle and is crucial for survival and establishment of infection. In tachyzoites,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::388c02178f1c623d3cfcded1ea6a214b
https://doi.org/10.1073/pnas.2219533120
https://doi.org/10.1073/pnas.2219533120