Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maryna Koskela"'
Autor:
Maryna Koskela, T. Petteri Piepponen, Maria Lindahl, Brandon K. Harvey, Jaan-Olle Andressoo, Vootele Võikar, Mikko Airavaara
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Craving for alcohol, in other words powerful desire to drink after withdrawal, is an important contributor to the development and maintenance of alcoholism. Here, we studied the role of GDNF (glial cell line-derived neurotrophic f
Externí odkaz:
https://doaj.org/article/02e01585df47494e9bba26c02a845904
Autor:
Maryna Koskela, Susanne Bäck, Vootele Võikar, Christopher T. Richie, Andrii Domanskyi, Brandon K. Harvey, Mikko Airavaara
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 189-200 (2017)
Drug addiction is a chronic brain disease and drugs of abuse cause long lasting neuroadaptations. Addiction is characterized by the loss of control over drug use despite harmful consequences, and high rates of relapse even after long periods of absti
Externí odkaz:
https://doaj.org/article/52ce1a55f9ca459eb8a0fa172ef269c5
Autor:
Anna-Maija Penttinen, Ilmari Parkkinen, Merja H. Voutilainen, Maryna Koskela, Susanne Bäck, Anna Their, Christopher T. Richie, Andrii Domanskyi, Brandon K. Harvey, Raimo K. Tuominen, Liina Nevalaita, Mart Saarma, Mikko Airavaara
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Glial cell line-derived neurotrophic factor (GDNF) is one of the most studied neurotrophic factors. GDNF has two splice isoforms, full-length pre-α-pro-GDNF (α-GDNF) and pre-β-pro-GDNF (β-GDNF), which has a 26 amino acid deletion in the pro-regio
Externí odkaz:
https://doaj.org/article/0e3d168a5c6044e79f9fcb0e3793f8c3
Autor:
Elisa Rahikkala, Lea Urpa, Bishwa Ghimire, Hande Topa, Mitja I. Kurki, Maryna Koskela, Mikko Airavaara, Eija Hämäläinen, Katri Pylkäs, Jarmo Körkkö, Helena Savolainen, Anu Suoranta, Aida Bertoli-Avella, Arndt Rolfs, Pirkko Mattila, Mark Daly, Aarno Palotie, Olli Pietiläinen, Jukka Moilanen, Outi Kuismin
Publikováno v:
European journal of human genetics : EJHG. 30(5)
Biallelic loss-of-function variants in the SMG9 gene, encoding a regulatory subunit of the mRNA nonsense-mediated decay (NMD) machinery, are reported to cause heart and brain malformation syndrome. Here we report five patients from three unrelated fa
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). 57(4)
Aims Recently we developed a model to study alcohol-seeking behaviour after withdrawal in a social context in female mice. The model raised several questions that we were eager to address to improve methodology. Methods In our model, female mice were
Autor:
Susanne Bäck, Brandon K. Harvey, Christopher T. Richie, Maryna Koskela, Mikko Airavaara, Vootele Voikar, Andrii Domanskyi
Publikováno v:
Neurobiology of Disease, Vol 97, Iss, Pp 189-200 (2017)
Drug addiction is a chronic brain disease and drugs of abuse cause long lasting neuroadaptations. Addiction is characterized by the loss of control over drug use despite harmful consequences, and high rates of relapse even after long periods of absti
Autor:
Merja H. Voutilainen, Anna-Maija Penttinen, Christopher T. Richie, Raimo K. Tuominen, Andrii Domanskyi, Anna Their, Mikko Airavaara, Ilmari Parkkinen, Brandon K. Harvey, Susanne Bäck, Maryna Koskela, Mart Saarma, Liina Nevalaita
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 9 (2018)
Frontiers in Neurology, Vol 9 (2018)
Glial cell line-derived neurotrophic factor (GDNF) is one of the most studied neurotrophic factors. GDNF has two splice isoforms, full-length pre-alpha-pro-GDNF (u-GDNF) and pre-beta-pro-GDNF (beta-GDNF), which has a 26 amino acid deletion in the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2b8fcc3ef6a37b862ed5b60e15218c
http://hdl.handle.net/10138/264661
http://hdl.handle.net/10138/264661
Publikováno v:
Behavioural brain research. 352
It is about half a century ago when the so-called "Wise model" to study alcohol drinking behavior in rats was established. The model was based on voluntary intermittent access to increasing concentrations of alcohol. We aimed to establish a model of