Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Maryna, Skok"'
Autor:
Olena Lykhmus, Olena Kalashnyk, Maryna Skok, Olena Deryabina, Olena Toporova, Ianina Pokholenko, Oksana Gorbatiuk, Vitalii Kordium
Publikováno v:
Exploration of Neuroscience, Vol 3, Iss 3, Pp 207-218 (2024)
Aim: The aim of this work was to study the effects of extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) on inflammation-impaired cognitive functions and the brain of mice. Methods: Young mice (~3-month-old) and aged mice (~18-mo
Externí odkaz:
https://doaj.org/article/5715096943164e88926d4630b4301cd9
Autor:
Olena Lykhmus, Wen-Yu Tzeng, Lyudmyla Koval, Kateryna Uspenska, Elizabeta Zirdum, Olena Kalashnyk, Olga Garaschuk, Maryna Skok
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117255- (2024)
Alzheimer’s disease (AD) is an age-dependent incurable neurodegenerative disorder accompanied by neuroinflammation, amyloid accumulation, and memory impairment. It begins decades before the first clinical symptoms appear, and identifying early biom
Externí odkaz:
https://doaj.org/article/8ee937a8cf594a62b9e8499b6ce17e54
Autor:
Maryna Skok
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100061- (2022)
Mammalian nicotinic acetylcholine receptors (nAChRs) were initially discovered as ligand-gated ion channels mediating fast synaptic transmission in the neuro-muscular junctions and autonomic ganglia. They were further found to be involved in a wide r
Externí odkaz:
https://doaj.org/article/f97be991ea0d49d1b31318f3d533dc7d
Autor:
Olena Kalashnyk, Olena Lykhmus, Lyudmyla Koval, Kateryna Uspenska, Maria Obolenskaya, Volodymyr Chernyshov, Serhiy Komisarenko, Maryna Skok
Publikováno v:
Biochemical and Biophysical Research Communications. 657:35-42
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Externí odkaz:
https://doaj.org/article/20ca8e71abab426db9fd8d8606e508d8
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2020)
Neuroinflammation accompanies or even precedes the development of cognitive changes in many brain pathologies, including Alzheimer’s disease. Therefore, dampening inflammatory reactions within the brain is a promising strategy for supporting cognit
Externí odkaz:
https://doaj.org/article/b882f3d1328e4ee5ac6268d99166fdd7
Autor:
Olena, Lykhmus, Olena, Kalashnyk, Lyudmyla, Koval, Olga, Krynina, Serhiy, Komisarenko, Maryna, Skok
Publikováno v:
Biochemical and Biophysical Research Communications. 622:57-63
COVID-19 is accompanied by strong inflammatory reaction and is often followed by long-term cognitive disorders. The fragment 674-685 of SARS-Cov-2 spike protein was shown to interact with α7 nicotinic acetylcholine receptor involved in regulating bo
Autor:
Maryna Skok, Olena Deryabina, Olena Lykhmus, Olena Kalashnyk, Kateryna Uspenska, Nadia Shuvalova, Ianina Pokholenko, Iryna Lushnikova, Kateryna Smozhanyk, Galyna Skibo, Vitalii Kordyum
Publikováno v:
Regenerative Medicine. 17:533-546
Background: The present research has been undertaken to study the therapeutic potential of mesenchymal stem cells (MSCs) for the treatment of neuroinflammation-induced cognitive disorders. Methods: Either umbilical cord or adipose MSCs were injected
Autor:
Olena Lykhmus, Lyudmyla Koval, Larysa Voytenko, Kateryna Uspenska, Serhiy Komisarenko, Olena Deryabina, Nadia Shuvalova, Vitalii Kordium, Alina Ustymenko, Vitalii Kyryk, Maryna Skok
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Neuroinflammation is regarded as one of the pathogenic factors of Alzheimer disease (AD). Previously, we showed that mice regularly injected with bacterial lipopolysaccharide (LPS) possessed the AD-like symptoms like episodic memory decline, elevated
Externí odkaz:
https://doaj.org/article/27b79e13054b44f0ae0f6dc22705c51e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1091 (2021)
Microglia, the innate immune cells of the brain, are commonly perceived as resident macrophages of the central nervous system (CNS). This definition, however, requires further specification, as under healthy homeostatic conditions, neither morphologi
Externí odkaz:
https://doaj.org/article/b47f9b8fe0054effbebdec044e166543