Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maryline Santerre"'
Autor:
Jenny Shrestha, Maryline Santerre, Charles N. S. Allen, Sterling P. Arjona, Carmen Merali, Ruma Mukerjee, Kumaraswamy Naidu Chitrala, Jin Park, Asen Bagashev, Viet Bui, Eliseo A. Eugenin, Salim Merali, Marcus Kaul, Jeannie Chin, Bassel E. Sawaya
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This
Externí odkaz:
https://doaj.org/article/34ed7172ee7742b284b32f138f58b797
Autor:
Charles N. S. Allen, Sterling P. Arjona, Maryline Santerre, Claudio De Lucia, Walter J. Koch, Bassel E. Sawaya
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
A significant number of patients infected with HIV-1 suffer from HIV-associated neurocognitive disorders (HAND) such as spatial memory impairments and learning disabilities (SMI-LD). SMI-LD is also observed in patients using combination antiretrovira
Externí odkaz:
https://doaj.org/article/dfbeaea26f8246c5aba526fae7f2ee93
Autor:
Charles N. S. Allen, Maryline Santerre, Sterling P. Arjona, Lea J. Ghaleb, Muna Herzi, Megan D. Llewellyn, Natalia Shcherbik, Bassel E. Sawaya
Publikováno v:
Viruses, Vol 14, Iss 5, p 983 (2022)
Clinical studies indicate that patients infected with SARS-CoV-2 develop hyperinflammation, which correlates with increased mortality. The SARS-CoV-2/COVID-19-dependent inflammation is thought to occur via increased cytokine production and hyperactiv
Externí odkaz:
https://doaj.org/article/414e03fc0890454ca7b5782a8b749974
Publikováno v:
Viruses, Vol 14, Iss 3, p 602 (2022)
Metabolic reprogramming is a hallmark of cancer and has proven to be critical in viral infections. Metabolic reprogramming provides the cell with energy and biomass for large-scale biosynthesis. Based on studies of the cellular changes that contribut
Externí odkaz:
https://doaj.org/article/b987ba9275d8402ab028eb609d870a85
Autor:
Matthew Grove, Hyukmin Kim, Maryline Santerre, Alexander J Krupka, Seung Baek Han, Jinbin Zhai, Jennifer Y Cho, Raehee Park, Michele Harris, Seonhee Kim, Bassel E Sawaya, Shin H Kang, Mary F Barbe, Seo-Hee Cho, Michel A Lemay, Young-Jin Son
Publikováno v:
eLife, Vol 6 (2017)
Nuclear exclusion of the transcriptional regulators and potent oncoproteins, YAP/TAZ, is considered necessary for adult tissue homeostasis. Here we show that nuclear YAP/TAZ are essential regulators of peripheral nerve development and myelin maintena
Externí odkaz:
https://doaj.org/article/eae26989c1b34d3cb0582278302e9660
Autor:
Jenny Shrestha, Maryline Santerre, Charles N. Allen, Sterling P. Arjona, Robert Hooper, Ruma Mukerjee, Marcus Kaul, Natalia Shcherbik, Jonathan Soboloff, Bassel E. Sawaya
Publikováno v:
Mitochondrion. 70:31-40
Autor:
Sterling P. Arjona, Charles N. S. Allen, Maryline Santerre, Scott Gross, Jonathan Soboloff, Rosemarie Booze, Bassel E. Sawaya
Publikováno v:
CNS neurosciencetherapeuticsREFERENCES. 29(1)
Mitochondrial-associated ER membranes (MAMs) control many cellular functions, including calcium and lipid exchange, intracellular trafficking, and mitochondrial biogenesis. The disruption of these functions contributes to neurocognitive disorders, su
Publikováno v:
All Life
Favipiravir and remdesivir, inhibitors of RNA-dependent RNA polymerase (RdRp) were recently suggested as a potential SARS-CoV2 inhibitors. Since favipiravir and remdesivir target a critical and a v...
Autor:
Jenny Shrestha, Maryline Santerre, Charles N. S. Allen, Sterling P. Arjona, Carmen Merali, Ruma Mukerjee, Kumaraswamy Naidu Chitrala, Jin Park, Asen Bagashev, Viet Bui, Eliseo A. Eugenin, Salim Merali, Marcus Kaul, Jeannie Chin, Bassel E. Sawaya
Publikováno v:
Frontiers in aging neuroscience. 14
HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2311
The use of primary mammalian neurons derived from embryonic central nervous system tissue is limited by the fact that once terminally differentiated into mature neurons, the cells can no longer be propagated. Transformed neuronal-like cell lines can