Výsledky vyhledávání - "Maryline Mancini-Bourgine"

Akademický článek

Changes to the natural killer cell repertoire after therapeutic hepatitis B DNA vaccination.

Autor: Daniel Scott-Algara, Maryline Mancini-Bourgine, Hélène Fontaine, Stanislas Pol, Marie-Louise Michel

Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8761 (2010)

Improvements to the outcome of adaptive immune responses could be achieved by inducing specific natural killer (NK) cell subsets which can cooperate with dendritic cells to select efficient T cell responses. We previously reported the induction or re

Externí odkaz: https://doaj.org/article/e3f436bbe06c4870a95b4c495dcd2d34

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TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice

Publikováno v: Gut

Objective To assess a new adenovirus-based immunotherapy as a novel treatment approach to chronic hepatitis B (CHB). Methods TG1050 is a non-replicative adenovirus serotype 5 encoding a unique large fusion protein composed of a truncated HBV Core, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b32a7bc2d82c6c1a6d47d89c8776ca0
https://doi.org/10.1136/gutjnl-2014-308041

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Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients

Autor: Florence Bayard, Qiang Deng, Dina Kremsdorf, Yu-Chun Lone, Marie-Louise Michel, Maryline Mancini-Bourgine, Patrick Soussan

Publikováno v: Journal of Virology. 81:4963-4972

Hepatitis B virus splice-generated protein (HBSP), encoded by a spliced hepatitis B virus RNA, was recently identified in liver biopsy specimens from patients with chronic active hepatitis B. We investigated the possible generation of immunogenic pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbab8ffebb2df73abc17a49d4e28417
https://doi.org/10.1128/jvi.02619-06

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Identification of novel HLA-DR1-restricted epitopes from the hepatitis B virus envelope protein in mice expressing HLA-DR1 and vaccinated human subjects

Autor: Yu-Chun Lone, Qiang Deng, David M. Ojcius, Marie-Louise Michel, François A. Lemonnier, Anthony Pajot, Marie-Noëlle Ungeheuer, Maryline Mancini-Bourgine

Publikováno v: Microbes and Infection. 8:2783-2790

Helper T lymphocytes that control CD8+ T-cell and antibody responses are key elements for the resolution of infection by the hepatitis B virus and for the development of effective immunological memory after hepatitis B vaccination. We have used H-2 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79546645bb9a2277f977bbe624bd320a
https://doi.org/10.1016/j.micinf.2006.08.009

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Traitement des infections chroniques dues au virus de l’hépatite B par vaccination thérapeutique

Autor: Maryline Mancini-Bourgine, Marie-Louise Michel

Publikováno v: Therapies. 60:257-265

Resume Le virus de l’hepatite B (VHB) est responsable de maladies chroniques du foie pouvant evoluer vers des cirrhoses et des carcinomes hepatocellulaires. On denombre plus de 370 millions d’individus porteurs chroniques de ce virus dans le mond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47ef4e87cc092f836ecaeaffffd4b259
https://doi.org/10.2515/therapie:2005033

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Plasmid vector-linked maturation of natural killer cells is coupled to antigen-dependent natural killer cell activation during DNA-based immunization in mice

Autor: Florence Bayard, Marie-Louise Michel, Qiang Deng, Xiao Ming Zhang, Maryline Mancini-Bourgine, R. Zhu

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2011, 85 (19), epub ahead of print. ⟨10.1128/JVI.00062-11⟩
Journal of Virology, 2011, 85 (19), epub ahead of print. ⟨10.1128/JVI.00062-11⟩

Plasmid DNA vaccines serve in a wide array of applications ranging from prophylactic vaccines to potential therapeutic tools against infectious diseases and cancer. In this study, we analyzed the mechanisms underlying the activation of natural killer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ce7d0398564448b7ed6dd33a29972e
https://hal-pasteur.archives-ouvertes.fr/pasteur-00616992/file/Ren_Zhu_J_Virol2011.pdf

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Therapeutic vaccines and immune-based therapies for the treatment of chronic hepatitis B: perspectives and challenges

Autor: Maryline Mancini-Bourgine, Qiang Deng, Marie-Louise Michel

Publikováno v: Journal of hepatology. 54(6)

The treatment of chronic hepatitis B virus (HBV) infection has greatly improved over the last 10 years, but alternative treatments are still needed. Therapeutic vaccination is a promising new strategy for controlling chronic infection. However, this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f290470fe39c65caea691660df117ea
https://pubmed.ncbi.nlm.nih.gov/21238516

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Hepatitis B virus as a gene delivery vector activating foreign antigenic T cell response that abrogates viral expression in mouse models

Autor: Xiaoming Zhang, Marie-Louise Michel, Marie-Christine Cumont, Maryline Mancini-Bourgine, Yu-Chun Lone, R. Zhu, Qiang Deng

Publikováno v: Hepatology
Hepatology, Wiley-Blackwell, 2009, epub ahead of print. ⟨10.1002/hep.23150⟩
Hepatology, 2009, epub ahead of print. ⟨10.1002/hep.23150⟩

International audience; Chronic hepatitis B virus (HBV) infection is characterized by functionally impaired T cell responses. To ensure active immunotherapy, the immune response must be switched from exhausted T cells to functional effectors that can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f48e61b4ff880a65fa610629f97517
https://hal-pasteur.archives-ouvertes.fr/pasteur-00425299

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