Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maryline Kienle"'
Autor:
Caroline S. Foo, Andréanne Lupien, Maryline Kienle, Anthony Vocat, Andrej Benjak, Raphael Sommer, Dirk A. Lamprecht, Adrie J. C. Steyn, Kevin Pethe, Jérémie Piton, Karl-Heinz Altmann, Stewart T. Cole
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT New drugs are needed to control the current tuberculosis (TB) pandemic caused by infection with Mycobacterium tuberculosis. We report here on our work with AX-35, an arylvinylpiperazine amide, and four related analogs, which are potent antit
Externí odkaz:
https://doaj.org/article/adb9ac67e2c14c6b855d0f2b8719a48c
Publikováno v:
Biochemistry. 61:2261-2266
Pyrimidine nucleotide biosynthesis in humans is a promising chemotherapeutic target for infectious diseases caused by RNA viruses. Because mammalian cells derive pyrimidine ribonucleotides through a combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c927f48e3caadc07ccd33fca9e30f76e
https://doi.org/10.1021/acs.biochem.2c00451
https://doi.org/10.1021/acs.biochem.2c00451
Autor:
Jake Hsu, Nina Fatuzzo, Nielson Weng, Wojciech Michno, Wentao Dong, Maryline Kienle, Yuqin Dai, Anca Pasca, Monther Abu-Remaileh, Natalie Rasgon, Benedetta Bigio, Carla Nasca, Chaitan Khosla
Publikováno v:
The Journal of biological chemistry.
In eukaryotes carnitine is best known for its ability to shuttle esterified fatty acids across mitochondrial membranes for β-oxidation. It also returns to the cytoplasm, in the form of acetyl-L-carnitine (LAC), some of the resulting acetyl groups fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cd7b69c27126f45775076bb193a4c2
https://pubmed.ncbi.nlm.nih.gov/36587768
https://pubmed.ncbi.nlm.nih.gov/36587768
Autor:
James F. Demarest, Maryline Kienle, RuthMabel Boytz, Mary Ayres, Eun Jung Kim, Donghoon Chung, Varsha Gandhi, Robert Davey, David B. Sykes, Nadim Shohdy, John C. Pottage, Vikram S. Kumar
The continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has compromised the efficacy of currently available vaccines and monoclonal antibody (mAb)-based treatment options for COVID-19. The limited number of authorized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21183e106121ec601043d816a72f4bfd
https://doi.org/10.1101/2022.03.30.486499
https://doi.org/10.1101/2022.03.30.486499
Autor:
Barbara Stoessel, Karl-Heinz Altmann, Stewart T. Cole, Samuel Hasler, Patrick Eisenring, Gwenaelle van Colen, Ruben C. Hartkoorn, Anthony Vocat, Oliver P. Horlacher, Maryline Kienle
Publikováno v:
Journal of Medicinal Chemistry, 63 (3)
A series of derivatives of the antimycobacterial natural product pyridomycin have been prepared with the C2 side chain attached to the macrocyclic core structure by a C-C single bond, in place of the synthetically more demanding enol ester double bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b68df5fa58299a5df4944ce533b6dad
https://doi.org/10.1021/acs.jmedchem.9b01457
https://doi.org/10.1021/acs.jmedchem.9b01457
Autor:
Raphael Sommer, Andréanne Lupien, Andrej Benjak, Maryline Kienle, Stewart T. Cole, Jérémie Piton, Anthony Vocat, Kevin Pethe, Karl-Heinz Altmann, Dirk A. Lamprecht, Caroline S. Foo, Adrie J. C. Steyn
Publikováno v:
mBio
mBio, Vol 9, Iss 5 (2018)
mBio, Vol 9, Iss 5, p e01276-18 (2018)
mBio, 9 (5)
mBio, Vol 9, Iss 5 (2018)
mBio, Vol 9, Iss 5, p e01276-18 (2018)
mBio, 9 (5)
New drugs against Mycobacterium tuberculosis are urgently needed to deal with the current global TB pandemic. We report here on the discovery of a series of arylvinylpiperazine amides (AX-35 to AX-39) that represent a promising new family of compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1a5f73d3a37d08af2bcace550c63e0
https://infoscience.epfl.ch/record/261842
https://infoscience.epfl.ch/record/261842