Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maryland Franklin"'
Autor:
Neil W. Gibson, Lee D. Arnold, Arlindo L. Castelhano, David L. Emerson, Frank Richardson, Tao Zhang, An-Hu Li, Regina Sennello, Karen Hart, Dwight Henninger, Bojana Vulevic, Anna Chan, Matthew O'Connor, Carrie Pirrit, Mary C. Srebernak, Chris Hidden, Paul Briner, John F. Keily, Mark A. Bittner, Eric N. Brown, April Franks, Shannon L. Winski, Jennifer Kahler, Linda Castaldo, Graham M. Wynne, Andrew R. Cooke, Maryland Franklin, Andrew P.A. Crew, Andrew J. Garton
Supplementary Figure Legends from OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d345aaadab65f3803036dfbbb909af
https://doi.org/10.1158/0008-5472.22366926.v1
https://doi.org/10.1158/0008-5472.22366926.v1
Autor:
Neil W. Gibson, Lee D. Arnold, Arlindo L. Castelhano, David L. Emerson, Frank Richardson, Tao Zhang, An-Hu Li, Regina Sennello, Karen Hart, Dwight Henninger, Bojana Vulevic, Anna Chan, Matthew O'Connor, Carrie Pirrit, Mary C. Srebernak, Chris Hidden, Paul Briner, John F. Keily, Mark A. Bittner, Eric N. Brown, April Franks, Shannon L. Winski, Jennifer Kahler, Linda Castaldo, Graham M. Wynne, Andrew R. Cooke, Maryland Franklin, Andrew P.A. Crew, Andrew J. Garton
Supplementary Tables 1-2 from OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce34b51937e71be251c0829e3f406e8
https://doi.org/10.1158/0008-5472.22366920
https://doi.org/10.1158/0008-5472.22366920
Autor:
Neil W. Gibson, Lee D. Arnold, Arlindo L. Castelhano, David L. Emerson, Frank Richardson, Tao Zhang, An-Hu Li, Regina Sennello, Karen Hart, Dwight Henninger, Bojana Vulevic, Anna Chan, Matthew O'Connor, Carrie Pirrit, Mary C. Srebernak, Chris Hidden, Paul Briner, John F. Keily, Mark A. Bittner, Eric N. Brown, April Franks, Shannon L. Winski, Jennifer Kahler, Linda Castaldo, Graham M. Wynne, Andrew R. Cooke, Maryland Franklin, Andrew P.A. Crew, Andrew J. Garton
Supplementary Figures 1-3 from OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2466cc8df2c7445a3647818bc7207ba8
https://doi.org/10.1158/0008-5472.22366923.v1
https://doi.org/10.1158/0008-5472.22366923.v1
Publikováno v:
Cancer Research. 81:2921-2921
Preclinical oncology studies aim to model human disease in animal settings. To this effect, the site of tumor implant is thought to impact critical parameters that determine response to treatment. The more frequently used subcutaneous (SC) models hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad95b3606da070e12337eb6373ce5ae
https://doi.org/10.1158/1538-7445.am2021-2921
https://doi.org/10.1158/1538-7445.am2021-2921
Publikováno v:
Cancer Research. 81:2711-2711
The development of immuno-oncology agents against human targets is actively pursued in the preclinical space using immune deficient mice with reconstituted human immune systems. We utilized a human peripheral blood mononuclear cell (hPBMC) based huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf26cfa6bfee18e28cf9c2af38150786
https://doi.org/10.1158/1538-7445.am2021-2711
https://doi.org/10.1158/1538-7445.am2021-2711
Autor:
Sylvie Kossodo, David Draper, Maryland Franklin, Sheri Barnes, Derrick Germain, Scott C. Wise
Publikováno v:
Cancer Research. 81:1562-1562
With 53,200 deaths expected in 2020, colorectal cancer (CRC) is the second most common cause of cancer deaths in the US. Metastatic lesions are common, and CRC remains incurable for many patients, leading to over 900,000 deaths per year worldwide. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a38fe8359889244dd6031ff21480bbc
https://doi.org/10.1158/1538-7445.am2021-1562
https://doi.org/10.1158/1538-7445.am2021-1562
Publikováno v:
Cancer Research. 81:2926-2926
Colorectal cancer (CRC) is a major contributor to the whole of cancer as a disease, representing 10% of all cases of cancer. Recent clinical studies and FDA approvals demonstrate strong possibilities for the future of immunotherapy in the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c3461fca141edc36008deaef81e20f
https://doi.org/10.1158/1538-7445.am2021-2926
https://doi.org/10.1158/1538-7445.am2021-2926
Publikováno v:
Cancer Research. 80:920-920
Radiotherapy (RT) is a highly utilized clinical treatment approach for certain types of breast cancer. The use of RT, in combination with checkpoint blockade, to prime and activate the immune system is an area of intensive research. Developing precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14a242666190f244f13516fb77eb883
https://doi.org/10.1158/1538-7445.am2020-920
https://doi.org/10.1158/1538-7445.am2020-920
Autor:
Maryland Franklin, Philip Lapinski, Brogan Yarzabek, Scott C. Wise, Hillary Evens, David W. Draper
Publikováno v:
Cancer Research. 80:5537-5537
Hepatocellular carcinoma (HCC) is the third leading cause of cancer related deaths and is refractory to standard chemo and radiation therapies. Clinical trials are tackling unresectable HCC through combination approaches using immunotherapies and hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70c9c1201c65f1930fe1e001b96482f
https://doi.org/10.1158/1538-7445.am2020-5537
https://doi.org/10.1158/1538-7445.am2020-5537
Publikováno v:
Cancer Research. 80:6650-6650
Clinically, most breast cancers are refractory to checkpoint inhibitor (CPI) monotherapy and are regarded as immunologically “cold” due to minimal tumor CD8+ T cell infiltrate and low immunogenicity. These characteristics have encouraged the eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9494cf72c509159683d677a9481ebb9
https://doi.org/10.1158/1538-7445.am2020-6650
https://doi.org/10.1158/1538-7445.am2020-6650