Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Maryellen F. Eckenhoff"'
Autor:
Jintao Wang, Yun Shi, Shuchun Yu, Yan Wang, Qingcheng Meng, Ge Liang, Maryellen F Eckenhoff, Huafeng Wei
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229156 (2020)
Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene's limited penetration into the CNS hampers its effectiveness as a neuroprotective agent. Here, we studied whether the intranasal admin
Externí odkaz:
https://doaj.org/article/ac377e32469a482aa897f0356c999acb
Autor:
Robert Vera, Nicholas Hong, Bailin Jiang, Grace Liang, Maryellen F Eckenhoff, Halle J Kincaid, Veron Browne, Vinolia Chellaraj, Douglas Gisewhite, Michael Greenberg, Sudhir Ranjan, Gaozhong Zhu, Huafeng Wei
Background Repurposing dantrolene as a potential disease-modifying treatment for Alzheimer’s disease has been shown to be effective in amyloid transgenic mouse models but has not been examined in a model of tauopathy.Objective The effects of a nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ae3f8ecb5bdd633fc9462dc9a77819
https://doi.org/10.21203/rs.3.rs-2802620/v1
https://doi.org/10.21203/rs.3.rs-2802620/v1
Autor:
Jing Zhang, Yun Shi, Matan Ben Abou, Qingcheng Meng, Adrian Hepner, Lei Zhang, Xue Gao, Maryellen F. Eckenhoff, Ge Liang, Huafeng Wei
Publikováno v:
Journal of Alzheimer's Disease
Background/objective This study compares the effectiveness and safety of intranasal versus subcutaneous administration of dantrolene in 5XFAD Alzheimer's disease (AD) mice. Methods 5XFAD and wild type (WT) B6SJLF1/J mice were treated with intranasal
Autor:
Deborah J. Culley, Robert A. Whittington, Zhiyi Zuo, Maryellen F. Eckenhoff, Roderic G. Eckenhoff, Zhongcong Xie, Beverley A. Orser, Huafeng Wei, Niccolò Terrando, Mervyn Maze, Sarah J. Goodlin
Publikováno v:
Anesthesiology. 132:55-68
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not inte
Autor:
Daniel A. Xu, Maryellen F. Eckenhoff, Nicholas P. Kondoleon, Roderic G. Eckenhoff, Timothy P. DeYoung
Publikováno v:
Anesthesia and analgesia. 133(5)
BACKGROUND Parkinson disease is a chronic and progressive movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The causes of Parkinson disease are not clear but may involve genetic suscepti
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52887 (2013)
Post-operative cognitive dysfunction has been widely observed, especially in older patients. An association of post-operative cognitive dysfunction with the neurodegenerative diseases, such as Alzheimer's disease, has been suggested. Neuroinflammatio
Externí odkaz:
https://doaj.org/article/c70a316d84104f28be32cb4a395a35ed
Autor:
Shuchun Yu, Huafeng Wei, Maryellen F. Eckenhoff, Qingcheng Meng, Ge Liang, Yun Shi, Yan Wang, Jintao Wang
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229156 (2020)
PLoS ONE
PLoS ONE
Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene's limited penetration into the CNS hampers its effectiveness as a neuroprotective agent. Here, we studied whether the intranasal admin
Autor:
Roderic G, Eckenhoff, Mervyn, Maze, Zhongcong, Xie, Deborah J, Culley, Sarah J, Goodlin, Zhiyi, Zuo, Huafeng, Wei, Robert A, Whittington, Niccolò, Terrando, Beverley A, Orser, Maryellen F, Eckenhoff
Publikováno v:
Anesthesiology, vol 132, iss 1
Anesthesiology
Anesthesiology
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bf62df9795eec0831363d306dc7cc92d
https://escholarship.org/uc/item/08w9h6r0
https://escholarship.org/uc/item/08w9h6r0
Autor:
Ying Cheng, Adia Thomas, Feras Mardini, Shannon L Bianchi, Junxia X Tang, Jun Peng, Huafeng Wei, Maryellen F Eckenhoff, Roderic G Eckenhoff, Richard J Levy
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32029 (2012)
Carbon monoxide (CO) exposure at high concentrations results in overt neurotoxicity. Exposure to low CO concentrations occurs commonly yet is usually sub-clinical. Infants are uniquely vulnerable to a variety of toxins, however, the effects of postna
Externí odkaz:
https://doaj.org/article/80c40d9e0d2c46cbb9a321fdd698cab1
Publikováno v:
Stroke. 49:1766-1769
Background and Purpose— To improve stroke awareness and reduce life-threatening prehospital delays worldwide, a universal stroke educational program is needed. To meet this unmet need, we developed a universal program without language barriers and