Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maryanne, Donovan"'
Publikováno v:
The Scientific World Journal, Vol 1, Pp 52-52 (2001)
Externí odkaz:
https://doaj.org/article/ccef10d126914e8f8e8a1892284c3ae4
Publikováno v:
Clinical & Experimental Ophthalmology. 39:243-251
Background: This paper seeks to investigate differences between the neonatal and adult retinal ganglion cell populations to apoptotic death stimuli. Design and Samples: In vitro and ex vivo paradigms involving P6 and P60 Sprague–Dawley rat retinal
Publikováno v:
Journal of Neurochemistry. 116:33-42
J. Neurochem. (2011) 116, 33–42. Abstract Programmed cell death is well established as a key factor in the development of the vertebrate nervous system of which the retina is a unique sensory component. However, it is of utmost importance for the s
Publikováno v:
Experimental Eye Research. 83:1482-1492
Apoptosis, a cellular process critical to retinal neurogenesis, has been implicated in several neurodegenerative disorders. As the retina matures the suppression of apoptosis occurs and the emphasis shifts towards survival. To identify the cellular c
Publikováno v:
European Journal of Neuroscience. 24:981-990
Apoptosis of photoreceptor cells in the early postnatal period is a normal feature of mammalian retinal development. The role of mitochondria and caspases in the process has been well established; however, the identification of key apoptotic mediator
Autor:
Maryanne Donovan, Thomas G. Cotter
Publikováno v:
Cell Death & Differentiation. 9:1220-1231
Apoptosis is the mode of photoreceptor cell death in many retinal dystrophies. Exposure of Balb/c mice to excessive levels of light induces photoreceptor apoptosis and represents an animal model for the study of retinal degenerations. Caspases have e
Publikováno v:
Journal of Biological Chemistry. 276:23000-23008
Apoptosis is the mode of photoreceptor cell death in inherited and induced retinal degeneration. However, the molecular mechanisms of photoreceptor cell death in human cases and animal models of retinal dystrophies remain undefined. Exposure of Balb/
Publikováno v:
Clinicalexperimental ophthalmology. 39(3)
This paper seeks to investigate differences between the neonatal and adult retinal ganglion cell populations to apoptotic death stimuli. DESIGN AND SAMPLES: In vitro and ex vivo paradigms involving P6 and P60 Sprague-Dawley rat retinal explants and r
Autor:
Aedín C. Culhane, B. D. Barry, M A Kelly, Henry Paul Redmond, Desmond G. Higgins, Jeffrey Tze-Yee Wang, Thomas G. Cotter, John Calvin Coffey, Myles Smith, Maryanne Donovan, W. O. Kirwan
Publikováno v:
British Journal of Cancer
Tumour stroma gene expression in biopsy specimens may obscure the expression of tumour parenchyma, hampering the predictive power of microarrays. We aimed to assess the utility of fluorescence-activated cell sorting (FACS) for generating cell populat
Autor:
Philippe Bouillet, Francesca Doonan, Violeta Gómez-Vicente, Thomas G. Cotter, Maryanne Donovan
Programmed cell death (PCD) during development of the mouse retina involves activation of the mitochondrial pathway. Previous work has shown that the multidomain Bcl-2 family proteins Bax and Bak are fundamentally involved in this process. To induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c801071f5312e57aab5b93f388ef4a3
https://europepmc.org/articles/PMC6672824/
https://europepmc.org/articles/PMC6672824/