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pro vyhledávání: '"Maryann Powles"'
Autor:
Gregory L, Adams, Francisco, Velazquez, Charles, Jayne, Unmesh, Shah, Shouwu, Miao, Eric R, Ashley, Maria, Madeira, Taro E, Akiyama, Jerry, Di Salvo, Takao, Suzuki, Nengxue, Wang, Quang, Truong, Eric, Gilbert, Dan, Zhou, Andreas, Verras, Melissa, Kirkland, Michele, Pachanski, Maryann, Powles, Wu, Yin, Feroze, Ujjainwalla, Srikanth, Venkatraman, Scott D, Edmondson
Publikováno v:
ACS medicinal chemistry letters. 8(1)
GPR120 (FFAR4) is a fatty acid sensing G protein coupled receptor (GPCR) that has been identified as a target for possible treatment of type 2 diabetes. A selective activator of GPR120 containing a chromane scaffold has been designed, synthesized, an
Autor:
Margaret Wu, Cai Li, Robert W. Myers, Michael R. Tota, Michael E. Lassman, Christine C. Chung, Maryann Powles, Corey N. Miller, Jun Wang, Bindhu V. Karanam, Gino Salituro, Sheo B. Singh, Kenneth P. Ellsworth, Bei B. Zhang, Sang Ho Lee
Platensimycin (PTM) is a recently discovered broad-spectrum antibiotic produced by Streptomyces platensis . It acts by selectively inhibiting the elongation-condensing enzyme FabF of the fatty acid biosynthesis pathway in bacteria. We report here tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06a8a194f9234738800a07d3d73077d
https://europepmc.org/articles/PMC3069196/
https://europepmc.org/articles/PMC3069196/