Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maryann Mikucki"'
Autor:
Oluwadamilola T. Oladeru, Anurag K. Singh, Sung Jun Ma, Maryann Mikucki, Mark K. Farrugia, Austin J. Iovoli, Amit Sood, Rohil Shekher
Publikováno v:
The Breast Journal. 27:27-34
Among patients with early-stage breast cancer and a high 21-gene recurrence score (RS) ≥ 26, it remains unclear on whether those with RS 26-30 would benefit from chemotherapy with a comparable magnitude as those with RS 30. In addition, RS 30 as an
Autor:
Maryann Mikucki, Sharon S. Evans, Jason B. Muhitch, Amy W. Ku, Daniel T. Fisher, Michelle M. Appenheimer
Publikováno v:
International Journal of Hyperthermia. 29:464-473
Cancer immunotherapy aims to generate long-lived, tumour-specific adaptive immunity to limit dysregulated tumour progression and metastasis. Tumour vasculature has emerged as a critical checkpoint controlling the efficacy of immunotherapy since it is
Autor:
Sharon S. Evans, Joseph J. Skitzki, Andrew D. Luster, Maryann Mikucki, Thomas F. Gajewski, Kunle Odunsi, John G. Frelinger
Publikováno v:
Oncoimmunology
Promising cancer immunotherapeutics depend on mobilization of cytotoxic T cells across tumor vascular barriers through mechanisms that are poorly understood. Recently, we discovered that the CXCR3 chemokine receptor uniquely functions as the master-r
Publikováno v:
Integrative and Comparative Biology. 44:275-283
Ethanol is an important environmental variable for fruit-breeding Drosophila species, serving as a resource at low levels and a toxin at high levels. The first step of ethanol metabolism, the conversion of ethanol to acetaldehyde, is catalyzed primar
Autor:
Elizabeth J. Grayhack, Maryann Mikucki, George T. DeTitta, Erin Quartley, Wim G. J. Hol, Eric M. Phizicky, Andrei Alexandrov, Frederick S. Buckner
Publikováno v:
Journal of structural and functional genomics. 10(3)
High level expression of many eukaryotic proteins for structural analysis is likely to require a eukaryotic host since many proteins are either insoluble or lack essential post-translational modifications when expressed in E. coli. The well-studied e
Autor:
Maryann Mikucki, Joseph Skitzki, Daniel Fisher, Kathryn Curry, John Frelinger, Andrew Luster, Sharon Evans
Publikováno v:
The Journal of Immunology. 190:170.25-170.25
Recent advances in the treatment of metastatic melanoma are designed to promote the cytotoxic CD8 T cell response (e.g., CTLA-4 blockade and adoptive cell transfer), but it remains poorly understood how T cells enter tumor tissues to contact tumor ta
Publikováno v:
The Journal of Immunology. 188:46.14-46.14
Trafficking of tumor-reactive T cells across vascular checkpoints is a critical juncture in the effector phase of cancer immunity although this step is largely unexplored. We recently showed that poor trafficking of blood-borne CD8 effector T cells a