Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maryana Gorshunska"'
Autor:
Nataliya Krasova, Alla Kolesnikova, Maryana Gorshunska, Olga Plohotnichenko, Tetiana Tyzhnenko, Zhanna Leshchenko, Oleksandr Gladkih, Tetiana Voropay, Iryna Romanova, Elena Zalubovskaya, Loriana Sergienko, Eugene Jansen, Kateryna Misiura
Publikováno v:
Problems of Endocrine Pathology. 80:36-42
Recently, the role of stress-regulatory pathways in the development and progression of type 2 diabetes mellitus (T2DM) and associated cardiovascular diseases has been widely investigated. The aim of the study was to assess the relationship of polymor
Autor:
Tetiana Tyzhnenko, Kateryna Misiura, Nonna Kravchun, Maryana Gorshunska, Artem Pochernyaev, Nataliya Krasova, Alexander Gladkih, Zhanna Leshchenko, Ganna Fedorova, Olga Plohotnichenko, Olena Hromakovska, Alla Kolesnikova, Eugene Jansen, Yurii Karachentsev, Viktoriia Poltorak
Publikováno v:
Problems of Endocrine Pathology. 79:42-52
Background. It is known that single nucleotide polymorphisms (SNPs) in adipokine genes can influence the development of pathological conditions associated with obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease and their complicatio
Publikováno v:
Problems of Endocrine Pathology. 49:97-104
The review is devoted to the role of sirtuins, particularly SIRT1, in the regulation of processesinvolved in the pathogenesis of obesity, insulin resistance, type 2 diabetes and its vascular complica-tions. Proved the perspectivity of SIRT1 use as a
Autor:
Maryana Gorshunska, Yuri Karachentsev, Nona Kravchun, L. A. Atramentova, A. I. Gladkih, Nataliya Krasova, Zhanna Leshchenko, T. V. Tyzhnenko, Yu. A. Opaleiko, A. K. Pochernyayev, V. V. Poltorak
Publikováno v:
Problems of Endocrine Pathology. 44:7-17
Single nucleotide polymorphism +276G > T of adiponectin gene (ADIPOQ) in type 2 diabetesmellitus patients (n=544) and healthy habitants (n = 215) of Kharkiv was studied. There wereno significant differences of single nucleotide polymorphism +276 G >
Autor:
Maryana Gorshunska, Yuri Karachentsev, Nona Kravchun, E. Jansen, L. O. Atramentova, Olexander Gladkih, Nataliya Krasova, Zhanna Leshchenko, T. V. Tyzhnenko, Y. A. Opaleiko, A. K. Pochernyaev, V. V. Роltorak
Publikováno v:
Problems of Endocrine Pathology. 43:5-14
In 61 type 2 diabetic patients it was defined single nucleotide polymorphism +276 G > T (rs1501299 ) in adiponectin gene and atherogenic potential dynamics (hormonal and metabolic parameters of insulin resistance, a pro-inflammatory state, oxidative
Autor:
Maryana Gorshunska
Publikováno v:
Problems of Endocrine Pathology. 42:126-137
Review is devoted to the metabolic impact and realization mechanisms of the effect of short and long-time omega-3 polyunsaturated fatty acid supplementation on classic and novel cardiovascular risk parameters, also in type 2 diabetes mellitus.
Publikováno v:
Problems of Endocrine Pathology. 41:91-103
The review is devoted to the pathogenic role of oxidative stress in specific and nonspecific diabeticvascular complications development. Perspectives of antioxidant therapy, in particular, α-lipoic acid,in order to restore redox homeostasis and el
Autor:
Maryana Gorshunska
Publikováno v:
Problems of Endocrine Pathology. 41:113-124
Review is devoted to the role of oxidative stress in the pathogenesis of type 2 diabetes mellitusand its vascular complications. We present multiple correlations of indicators that comprehensivelycharacterize oxidative stress, with classic and novel
Autor:
Maryana Gorshunska
Publikováno v:
Problems of Endocrine Pathology. 40:91-107
The article reviewed world literature data along with own study findings regarding different multimeric adiponectin complexes, their functional activity and contribution of high molecular weight adiponectin as the most biologically active multimeric
Autor:
Maryana Gorshunska
Publikováno v:
Problems of Endocrine Pathology. 39:5-15
61 middle-age overweight or obese patients with type 2 diabetes mellitus were studied. Patients were characterized by hormonal and metabolic parameters of insulin resistance (fasting hyperinsulinemia, both enhanced HOMA-IR indices and circulating fre