55/52Mn2+ Complexes with a Bispidine-Phosphonate Ligand: High Kinetic Inertness for Imaging Applications

Autor: Maryame Sy, Daouda Ndiaye, Isidro da Silva, Sara Lacerda, Loïc J. Charbonnière, Éva Tóth, Aline M. Nonat

Publikováno v: Inorganic Chemistry
Inorganic Chemistry, 2022, 61 (34), pp.13421-13432. ⟨10.1021/acs.inorgchem.2c01681⟩

International audience; Bispidine (3,7-diazabicyclo[3.3.1]nonane) provides a rigid and preorganized scaffold that is particularly interesting for the stable and inert complexation of metal ions, especially for their application in medical imaging. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc85993f5a248c6c7c23e3a07e5c24e
https://doi.org/10.1021/acs.inorgchem.2c01681

Unprecedented kinetic inertness for a Mn2+‐bispidine chelate: a novel structural entry for Mn2+‐based imaging agents

Autor: Aline Nonat, Éva Tóth, Daouda Ndiaye, Loïc J. Charbonnière, Sandra Même, Maryame Sy, Isidro de Silva, Sara Lacerda, Agnès Pallier

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2020, 59 (29), pp.11958-11963. ⟨10.1002/anie.202003685⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (29), pp.11958-11963. ⟨10.1002/anie.202003685⟩

International audience; The search for more biocompatible alternatives to Gd 3+-based MRI agents, and the interest in 52 Mn for PET imaging call for ligands that form inert Mn 2+ chelates. Given the labile nature of Mn 2+ , high inertness is challeng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac1ef8e9b3d51fe1005236db82ad7b9
https://hal.science/hal-02555574/document

Innenrücktitelbild: Unprecedented Kinetic Inertness for a Mn 2+ ‐Bispidine Chelate: A Novel Structural Entry for Mn 2+ ‐Based Imaging Agents (Angew. Chem. 29/2020)

Autor: Maryame Sy, Éva Tóth, Daouda Ndiaye, Isidro Da Silva, Aline Nonat, Loïc J. Charbonnière, Sandra Même, Agnès Pallier, Sara Lacerda

Publikováno v: Angewandte Chemie. 132:12319-12319

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51b2c19a6f0aa09464b5392bc16ccc53
https://doi.org/10.1002/ange.202007161

Structural Variations in Carboxylated Bispidine Ligands: Influence of Positional Isomerism and Rigidity on the Conformation, Stability, Inertness and Relaxivity of their Mn²⁺ Complexes.

Autor: Ndiaye, Daouda¹ (AUTHOR), Sy, Maryame² (AUTHOR), Thor, Waygen² (AUTHOR), Charbonnière, Loïc J.² (AUTHOR) aline.nonat@unistra.fr, Nonat, Aline M.² (AUTHOR) l.charbonn@unistra.fr, Tóth, Éva¹ (AUTHOR) eva.jakabtoth@cnrs-orleans.fr

Publikováno v: Chemistry - A European Journal. 11/8/2023, Vol. 29 Issue 62, p1-13. 13p.

Unprecedented Kinetic Inertness for a Mn²⁺‐Bispidine Chelate: A Novel Structural Entry for Mn²⁺‐Based Imaging Agents.

Autor: Ndiaye, Daouda¹ (AUTHOR), Sy, Maryame² (AUTHOR), Pallier, Agnès¹ (AUTHOR), Même, Sandra¹ (AUTHOR), Silva, Isidro³ (AUTHOR), Lacerda, Sara¹ (AUTHOR), Nonat, Aline M.² (AUTHOR), Charbonnière, Loïc J.² (AUTHOR) L.Charbonn@unistra.fr, Tóth, Éva¹ (AUTHOR) eva.jakabtoth@cnrs-orleans.fr

Publikováno v: Angewandte Chemie. 7/13/2020, Vol. 132 Issue 29, p12056-12061. 6p.