Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maryam Hafeji"'
Autor:
Alison E. John, Rebecca H. Graves, K. Tao Pun, Giovanni Vitulli, Ellen J. Forty, Paul F. Mercer, Josie L. Morrell, John W. Barrett, Rebecca F. Rogers, Maryam Hafeji, Lloyd I. Bibby, Elaine Gower, Valerie S. Morrison, Yim Man, James A. Roper, Jeni C. Luckett, Lee A. Borthwick, Ben S. Barksby, Rachel A. Burgoyne, Rory Barnes, Joelle Le, David J. Flint, Susan Pyne, Anthony Habgood, Louise A. Organ, Chitra Joseph, Rochelle C. Edwards-Pritchard, Toby M. Maher, Andrew J. Fisher, Natasja Stæhr Gudmann, Diana J. Leeming, Rachel C. Chambers, Pauline T. Lukey, Richard P. Marshall, Simon J. F. Macdonald, R. Gisli Jenkins, Robert J. Slack
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The αvβ6 integrin is key in activating the pro-fibrotic cytokine TGFβ in idiopathic pulmonary fibrosis. Here, the authors show an inhaled small molecule αvβ6 inhibitor GSK3008348 induces prolonged inhibition of TGFβ signaling pathways in human
Externí odkaz:
https://doaj.org/article/0b6e5916f4cb4d2e9b4186f07f1b86ee
Autor:
Natasja Stæhr Gudmann, Richard P. Marshall, Jeni Luckett, Rebecca F. Rogers, Robert J. Slack, Simon J. F. Macdonald, Diana Julie Leeming, Rachel C. Chambers, Joelle Le, Pauline T. Lukey, Anthony Habgood, Paul F. Mercer, Rachel A. Burgoyne, Ben S. Barksby, Lloyd I. Bibby, Yim Man, Maryam Hafeji, Andrew J. Fisher, David J. Flint, Toby M. Maher, Louise Organ, Susan Pyne, Lee A. Borthwick, James A. Roper, Valerie S. Morrison, Alison E. John, Giovanni Vitulli, Rebecca H. Graves, Rochelle C. Edwards-Pritchard, R. Gisli Jenkins, John Barrett, Josie Morrell, K. Tao Pun, Elaine Gower, Rory Barnes, Ellen J. Forty, Chitra Joseph
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
The αvβ6 integrin plays a key role in the activation of transforming growth factor-β (TGFβ), a pro-fibrotic mediator that is pivotal to the development of idiopathic pulmonary fibrosis (IPF). We identified a selective small molecule αvβ6 RGD-mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b4959cf67302e9783a88dddd530b0b
https://doaj.org/article/0b6e5916f4cb4d2e9b4186f07f1b86ee
https://doaj.org/article/0b6e5916f4cb4d2e9b4186f07f1b86ee
Autor:
Helen Hickey, Zaynab Chatoo, Maryam Hafeji, Molla Imaduddin Ahmed, Kamini Jain, Ben Elkington
Publikováno v:
Paediatric respiratory epidemiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70da6c45d7368047acf1d734e76fa72
https://doi.org/10.1183/13993003.congress-2020.3114
https://doi.org/10.1183/13993003.congress-2020.3114
Autor:
Rebecca F. Rogers, Steve Ludbrook, David J. Flint, Jane Denyer, John Marshall, Susan Pyne, Maryam Hafeji, Robert J. Slack
A20FMDV2 is a peptide derived from the foot-and-mouth disease virus with a high affinity and selectivity for the alpha-v beta-6 (αvβ6) arginyl-glycinyl-aspartic acid (RGD)-binding integrin. It has been shown to be an informative tool ligand in pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e2902c8acffe79e87fbd6f7028ea52
https://strathprints.strath.ac.uk/55205/1/Slack_etal_Pharmacology2016_v_6_integrin_binding_and_internalization_kinetics_of_the_foot_and_mouth.pdf
https://strathprints.strath.ac.uk/55205/1/Slack_etal_Pharmacology2016_v_6_integrin_binding_and_internalization_kinetics_of_the_foot_and_mouth.pdf
