Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Maryam Goudarzi"'
Autor:
Rakhee Banerjee, Rachel C. Hohe, Shijie Cao, Bryan M. Jung, Anthony J. Horak, Iyappan Ramachandiran, William J. Massey, Venkateshwari Varadharajan, Natalie I. Zajczenko, Amy C. Burrows, Sumita Dutta, Maryam Goudarzi, Kala Mahen, Abigail Carter, Robert N. Helsley, Scott M. Gordon, Richard E. Morton, Christopher Strauch, Belinda Willard, Camelia Baleanu Gogonea, Valentin Gogonea, Matteo Pedrelli, Paolo Parini, J. Mark Brown
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction:The Aster-C protein (encoded by the Gramd1c gene) is an endoplasmic reticulum (ER) resident protein that has been reported to transport cholesterol from the plasma membrane to the ER. Although there is a clear role for the closely-relate
Externí odkaz:
https://doaj.org/article/a67ae9a7639840f1997cab8381632bbb
Autor:
Ali Vaziri-Gohar, Jonathan J. Hue, Ata Abbas, Hallie J. Graor, Omid Hajihassani, Mehrdad Zarei, George Titomihelakis, John Feczko, Moeez Rathore, Sylwia Chelstowska, Alexander W. Loftus, Rui Wang, Mahsa Zarei, Maryam Goudarzi, Renliang Zhang, Belinda Willard, Li Zhang, Adam Kresak, Joseph E. Willis, Gi-Ming Wang, Curtis Tatsuoka, Joseph M. Salvino, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is highly resistant to chemotherapy. Effective alternative therapies have yet to emerge, as chemotherapy remains the best available systemic treatment. However, the discovery of safe and available adju
Externí odkaz:
https://doaj.org/article/d2faef86ea85483498c70286f6d2ac00
Autor:
Jonathan P. Jacobs, Maryam Goudarzi, Venu Lagishetty, Dalin Li, Tytus Mak, Maomeng Tong, Paul Ruegger, Talin Haritunians, Carol Landers, Philip Fleshner, Eric Vasiliauskas, Andrew Ippoliti, Gil Melmed, David Shih, Stephan Targan, James Borneman, Albert J. Fornace, Dermot P. B. McGovern, Jonathan Braun
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic risk on these microbi
Externí odkaz:
https://doaj.org/article/fe92c4592aad437cb5c862f197cb01d1
Autor:
Di Cui, Jianneng Li, Ziqi Zhu, Michael Berk, Aimalie Hardaway, Jeffrey McManus, Yoon-Mi Chung, Mohammad Alyamani, Shelley Valle, Ritika Tiwari, Bangmin Han, Maryam Goudarzi, Belinda Willard, Nima Sharifi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
After androgen deprivation, prostate cancer frequently becomes castration resistant (CRPC), with intratumoral androgen production from extragonadal precursors that activate the androgen receptor pathway. 3β-Hydroxysteroid dehydrogenase-1 (3βHSD1) i
Externí odkaz:
https://doaj.org/article/35efcccf9f7f4527b57a4702b4953aac
Autor:
Rebecca C Schugar, Christy M Gliniak, Lucas J Osborn, William Massey, Naseer Sangwan, Anthony Horak, Rakhee Banerjee, Danny Orabi, Robert N Helsley, Amanda L Brown, Amy Burrows, Chelsea Finney, Kevin K Fung, Frederick M Allen, Daniel Ferguson, Anthony D Gromovsky, Chase Neumann, Kendall Cook, Amy McMillan, Jennifer A Buffa, James T Anderson, Margarete Mehrabian, Maryam Goudarzi, Belinda Willard, Tytus D Mak, Andrew R Armstrong, Garth Swanson, Ali Keshavarzian, Jose Carlos Garcia-Garcia, Zeneng Wang, Aldons J Lusis, Stanley L Hazen, Jonathan Mark Brown
Publikováno v:
eLife, Vol 11 (2022)
Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host. Here, we show that gut microbe-targeted inhibition of the trimethylamine N-oxide
Externí odkaz:
https://doaj.org/article/1bf775b855894d52aa435ffcd48a01d8
Autor:
Robert A. Quinn, Kehau A. Hagiwara, Ken Liu, Maryam Goudarzi, Wimal Pathmasiri, Lloyd W. Sumner, Thomas O. Metz
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
Externí odkaz:
https://doaj.org/article/49f970953cbe4d74b8eb89649cf77558
Autor:
Robert A. Quinn, Kehau A. Hagiwara, Ken Liu, Maryam Goudarzi, Wimal Pathmasiri, Lloyd W. Sumner, Thomas O. Metz
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
ABSTRACT Metabolites from the microbiome influence human, animal, and environmental health, but the diversity and functional roles of these compounds have only begun to be elucidated. Comprehensively characterizing these molecules are significant cha
Externí odkaz:
https://doaj.org/article/24999a07de3a4ef6b765eefc20e853a0
Autor:
Wenjie Zheng, Xiuhua Wu, Maryam Goudarzi, Jing Shi, Wei Song, Chaoran Li, Jinjing Liu, Hua Chen, Xuan Zhang, Xiaofeng Zeng, Heng-Hong Li
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background The diagnosis of Behçet’s disease (BD) remains challenging due to the lack of diagnostic biomarkers. This study aims to identify potential serum metabolites associated with BD and its disease activity. Methods Medical records a
Externí odkaz:
https://doaj.org/article/6ba23c5796f74f05884a3a73963d62d1
Autor:
Jonathan P. Jacobs, Maryam Goudarzi, Namita Singh, Maomeng Tong, Ian H. McHardy, Paul Ruegger, Miro Asadourian, Bo-Hyun Moon, Allyson Ayson, James Borneman, Dermot P.B. McGovern, Albert J. Fornace, Jr., Jonathan Braun, Marla Dubinsky
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 6, Pp 750-766 (2016)
Background & Aims: Microbes may increase susceptibility to inflammatory bowel disease (IBD) by producing bioactive metabolites that affect immune activity and epithelial function. We undertook a family based study to identify microbial and metabolic
Externí odkaz:
https://doaj.org/article/5b85786fde5b4825a158fb3d16ff066c
Autor:
Heng-Hong Li, Yun-Tien Lin, Evagelia C. Laiakis, Maryam Goudarzi, Waylon Weber, Albert J. Fornace
Publikováno v:
Metabolites, Vol 10, Iss 7, p 270 (2020)
Our laboratory and others have use radiation metabolomics to assess responses in order to develop biomarkers reflecting exposure and level of injury. To expand the types of exposure and compare to previously published results, metabolomic analysis ha
Externí odkaz:
https://doaj.org/article/2d4ccfadd1e943be8fa77565e170bc33