Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maryam Ghufran"'
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract The tumor suppressor p53 when undergoes amyloid formation confers several gain-of-function (GOF) activities that affect molecular pathways crucial for tumorigenesis and progression like some of the p53 mutants. Even after successful cancer t
Externí odkaz:
https://doaj.org/article/9e0eedefb1e044b5b1575da8ac6d52d3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The activated hepatic stellate cells (HSCs) are the major cells that secrete the ECM proteins and drive the pathogenesis of fibrosis in chronic liver disease. Targeting of HSCs by modulating their activation and proliferation has emerged as
Externí odkaz:
https://doaj.org/article/db4a1624ddb64174a88991a2f9c69d8e
Autor:
Meenakshi Gupta, Shaikh Maryam Ghufran, Tasneem Kausar, Rafat Ali, Subhrajit Biswas, Shahid M. Nayeem, Romana Ishrat, Sher Ali, Ajaz Ahmad, Irfan A. Rather, Maryam Sarwat
Publikováno v:
Molecules, Vol 27, Iss 16, p 5104 (2022)
An ancient saffron-based polyherbal formulation, Dawa-ul-Kurkum (DuK), has been used to treat liver ailments and other diseases and was recently evaluated for its anticancer potential against hepatocellular carcinoma (HCC) by our research team. To ga
Externí odkaz:
https://doaj.org/article/47bd42e63de34a54860362632014017f
Autor:
Shaikh Maryam Ghufran, Prachi Sharma, Bornika Roy, Shivani Jaiswal, Mehreen Aftab, Shinjinee Sengupta, Sampa Ghose, Subhrajit Biswas
Publikováno v:
Genomics. 115:110642
Publikováno v:
Microvascular research. 142
During the progression of hepatocellular carcinoma (HCC), several angiogenic factors are overexpressed in the hepatic microenvironment, which play a critical role in governing the phenotype of the endothelial cells. Mutation in the p53 gene (TP53) is
Publikováno v:
Molecular biology reports.
Tumor necrosis factor-α (TNFα) is a pleiotropic cytokine involved in nuclear factor kappa B (NF-κB) mediated cell survival as well as cell death. High serum TNFα levels correlate with liver fibrosis and enhance hepatic stellate cell (HSC) viabili
Publikováno v:
Cancer Cell Metabolism: A Potential Target for Cancer Therapy ISBN: 9789811519901
An obscure metabolic network controls the activities of the cancer cells and their microenvironment which still continues to be unraveled. Cancer cells modify the biochemistry of the extracellular environment, which bring about multiple consequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05991ea10281312c074d88cf3f5d5ca2
https://doi.org/10.1007/978-981-15-1991-8_5
https://doi.org/10.1007/978-981-15-1991-8_5
Autor:
Basundhara Das, Subhrajit Biswas, Sampa Ghose, Shaikh Maryam Ghufran, Bornika Roy, Sachin Sharma
Publikováno v:
Life Sciences. 287:120119
Aim Hepatic fibrosis in injured liver is characterized by the activation of hepatic stellate cells (HSCs) from their quiescent state. Survivin (BIRC5) is one of the key genes that are upregulated during activation of HSCs but their role in HSC activa
Autor:
Aarti Singh, Subhrajit Biswas, Monalisa Mukherjee, Dakshi Kochhar, Piyush Garg, Amit Tyagi, Sampathkumar Jeevanandham, Lalita Mehra, Dinesh Kalyanasundaram, Sandip Chakrabarti, Sujata Sangam, Adeeba Shakeel, Rohan Bhattacharya, Maryam Ghufran
Publikováno v:
ACS nano. 13(8)
Graphene quantum dots (GQDs) are the harbingers of a paradigm shift that revitalize self-assembly of the colloidal puzzle by adding shape and size to the material-design palette. Although self-assembly is ubiquitous in nature, the extent to which the