Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maryam Ghaderi-Najafabadi"'
Autor:
Nima Abbasian, Maryam Ghaderi-Najafabadi, Emma Watson, Jeremy Brown, Li Yu si, Debbie Bursnall, Izabella Pawluczyk, Anne-Marie Seymour, Alan Bevington
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Taurine depletion occurs in patients with end-stage chronic kidney disease (CKD). In contrast, in the absence of CKD, plasma taurine is reported to increase following dietary L-glutamine supplementation. This study tested the hypo
Externí odkaz:
https://doaj.org/article/818dd5fbef81431488faeb43ce7c2734
Autor:
Maryam Ghaderi Najafabadi, G. Kenneth Gray, Li Ren Kong, Komal Gupta, David Perera, Huw Naylor, Joan S. Brugge, Ashok R. Venkitaraman, Mona Shehata
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Germline BRCA2 mutation carriers frequently develop luminal-like breast cancers, but it remains unclear how BRCA2 mutations affect mammary epithelial subpopulations. Here, we report that monoallelic Brca2 mut/WT mammary organoids subjected t
Externí odkaz:
https://doaj.org/article/f836acac45844291bd635b3b1255cb55
Autor:
Maryam Ghaderi Najafabadi, G. Kenneth Gray, Li Ren Kong, Komal Gupta, David Perera, Joan Brugge, Ashok Venkitaraman, Mona Shehata
BRCA2 mutation carriers preferentially develop luminal-like breast cancers, but it remains unclear how BRCA2 mutations affect mammary epithelial subpopulations. Here, we report that Brca2mut/WTmammary organoids subjected to replication stress activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::650016f5fe89e007061436aa56579751
https://doi.org/10.1101/2022.11.14.516328
https://doi.org/10.1101/2022.11.14.516328
Autor:
Debbie Bursnall, Maryam Ghaderi-Najafabadi, Alan Bevington, Emma L. Watson, Li Yu si, Izabella Z.A. Pawluczyk, Nima Abbasian, Jeremy R Brown, Anne-Marie L. Seymour
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Nephrology
BMC Nephrology
Background Taurine depletion occurs in patients with end-stage chronic kidney disease (CKD). In contrast, in the absence of CKD, plasma taurine is reported to increase following dietary L-glutamine supplementation. This study tested the hypothesis th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2945a249abbf06a6ef74ba1f75fce170
https://doaj.org/article/818dd5fbef81431488faeb43ce7c2734
https://doaj.org/article/818dd5fbef81431488faeb43ce7c2734
Autor:
Gavin E. Morris, Matthew J. Denniff, Elisavet Karamanavi, Sarah A. Andrews, Renata B. Kostogrys, Vasiliki Bountziouka, Maryam Ghaderi‐Najafabadi, Noor Shamkhi, George McConnell, Michael A. Kaiser, Laura Carleton, Christine Schofield, Thorsten Kessler, Richard D. Rainbow, Nilesh J. Samani, Thomas R. Webb
Publikováno v:
British journal of pharmacology. 179(21)
Vascular tone is regulated by the relative contractile state of vascular smooth muscle cells (VSMCs). Several integrins directly modulate VSMC contraction by regulating calcium influx through L-type voltage-gated CaSVEP1 and integrin binding were con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732d606e6ed84edb06800a5b26403708
https://pubmed.ncbi.nlm.nih.gov/35802072
https://pubmed.ncbi.nlm.nih.gov/35802072
Autor:
Matthias, Prestel, Caroline, Prell-Schicker, Tom, Webb, Rainer, Malik, Barbara, Lindner, Natalie, Ziesch, Monika, Rex-Haffner, Simone, Röh, Thanatip, Viturawong, Manuel, Lehm, Michal, Mokry, Hester, den Ruijter, Saskia, Haitjema, Yaw, Asare, Flavia, Söllner, Maryam Ghaderi, Najafabadi, Rédouane, Aherrahrou, Mete, Civelek, Nilesh J, Samani, Matthias, Mann, Christof, Haffner, Martin, Dichgans
Publikováno v:
Stroke. 50(10)
Background and Purpose- Genome-wide association studies have identified the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::588dee4b97697d50b13d29968ebfa744
https://pubmed.ncbi.nlm.nih.gov/31500558
https://pubmed.ncbi.nlm.nih.gov/31500558
Autor:
Martin Dichgans, Rainer Malik, Nilesh J. Samani, Flavia Söllner, Tom R. Webb, Natalie Ziesch, Thanatip Viturawong, Monika Rex-Haffner, Manuel Lehm, Barbara Lindner, Mete Civelek, Michal Mokry, Maryam Ghaderi Najafabadi, Redouane Aherrahrou, Matthias Prestel, Simone Röh, Yaw Asare, Christof Haffner, Caroline Prell-Schicker, Hester M. den Ruijter, Saskia Haitjema, Matthias Mann
Publikováno v:
Stroke
Stroke, 50(10), 2651. Lippincott Williams and Wilkins
Stroke, 50(10), 2651. Lippincott Williams and Wilkins
Background and Purpose— Genome-wide association studies have identified the HDAC9 (histone deacetylase 9) gene region as a major risk locus for atherosclerotic stroke and coronary artery disease in humans. Previous results suggest a role of altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d5dfc99eec026aa47ad2eb6cf51bef
Autor:
Keith M. Channon, Theodosios Kyriakou, Johan L.M. Björkegren, Sarah L. Andrews, Shu Ye, Maryam Ghaderi Najafabadi, Gillian Douglas, Nilesh J. Samani, Tom R. Webb, Simon Koplev, Peter Jones, Michael A. Kaiser, Rathinasabapathy Rajmohan, Hugh Watkins, Xia Yang, Yuqi Zhao
Objective— A large number of genetic loci have been associated with risk of coronary artery disease (CAD) through genome-wide association studies, however, for most loci the underlying biological mechanism is unknown. Determining the molecular path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146f77a783e04e7a9d7c1e4b44d9ab11
https://europepmc.org/articles/PMC6296439/
https://europepmc.org/articles/PMC6296439/
Autor:
Yuqi Zhao, Mike Kaiser, Sarah L. Andrews, Gillian Douglas, Xia Yang, Keith M. Channon, Theodosios Kyriakou, Johan L.M. Björkegren, Simon Koplev, Maryam Ghaderi Najafabadi, Rathinasabapathy Rajmohan, Hugh Watkins, Tom R. Webb, Shu Ye, Peter Jones, Nilesh J. Samani
Publikováno v:
Basic Science.
Genome-wide association studies have associated a large number of loci with coronary artery disease (CAD) risk. The CAD-associated variants at 10 p11.23 fall in JCAD, which encodes an endothelial junction protein. We set out to investigate the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd91c7ce1b8f313541cba5bcf4311ee
https://doi.org/10.1136/heartjnl-2018-bcs.83
https://doi.org/10.1136/heartjnl-2018-bcs.83
Autor:
Samita R. Patel, Peter Topham, Priyanka Desai, Izabella Z.A. Pawluczyk, Maryam Ghaderi Najafabadi, Dipti Vashi, Moin A. Saleem
Publikováno v:
Experimental Cell Research. 320:258-268
Sialoglycoproteins make a significant contribution to the negative charge of the glomerular anionic glycocalyx-crucial for efficient functioning of the glomerular permselective barrier. Defects in sialylation have serious consequences on podocyte fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b00ae76c847570dd825f3b9c485410
https://doi.org/10.1016/j.yexcr.2013.10.017
https://doi.org/10.1016/j.yexcr.2013.10.017