Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maryam Asadikorayem"'
Autor:
Patrick Weber, Kajetana Bevc, David Fercher, Sami Kauppinen, Shipin Zhang, Maryam Asadikorayem, Lucia Baixauli Marin, Tanqi Zhang, Tuomas Frondelius, Gian Salzmann, Valentino Bruhin, Jakob Hax, Gonçalo Barreto, Mikko A.J. Finnilä, Marcy Zenobi-Wong
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100539- (2024)
Objective: To characterize inflammatory and mechanical changes in the collagenase-induced OA (CIOA) model in rats. Design: Skeletally mature, 6-month-old Wistar rats received unilateral intraarticular injections of saline, 500 U or 1000 U of collagen
Externí odkaz:
https://doaj.org/article/66de505df6ef4f6bb3a0a04dda5c36f8
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101049- (2024)
Improving the pharmacokinetics of intra-articularly injected therapeutics is a major challenge in treating joint disease. Small molecules and biologics are often cleared from the joint within hours, which greatly reduces their therapeutic efficacy. F
Externí odkaz:
https://doaj.org/article/206924424462481da1068e33852525d3
Publikováno v:
Acta Biomaterialia, 166
Cell-based therapies for articular cartilage lesions are expensive and time-consuming; clearly, a one-step procedure to induce endogenous repair would have significant clinical benefits. Acellular heterogeneous granular hydrogels were explored for th