Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maryam Alapa"'
Autor:
Danny V. Jeyaraju, Maryam Alapa, Ann Polonskaia, Alberto Risueño, Prakash Subramanyam, Amit Anand, Kaushik Ghosh, Charalampos Kyriakopoulos, Daiane Hemerich, Rose Hurren, Xiaoming Wang, Marcela Gronda, Aarif Ahsan, Hsiling Chiu, Geethu Thomas, Evan F. Lind, Daniel L Menezes, Aaron D. Schimmer, Patrick R. Hagner, Anita Gandhi, Anjan G. Thakurta
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Oral azacitidine (oral-Aza) treatment results in longer median overall survival (OS) (24.7 vs. 14.8 months in placebo) in patients with acute myeloid leukemia (AML) in remission after intensive chemotherapy. The dosing schedule of oral-Aza (14 days/2
Externí odkaz:
https://doaj.org/article/1da3b8771381489588b67244fd735638
Autor:
Danny V Jeyaraju, Sheida Hayati, Ann Polonskaia, Maryam Alapa, Manuel Ugidos, Andrew Browne, Alberto Risueño, Patrick Hagner, Vikas Gupta, Moshe Talpaz, Christopher Hernandez, Vincent Chia, Patricia Martin-Regueira, Daniel Lopes de Menezes, Ross La Motte-Mohs, Rajasekhar NVS Suragani, Anita K. Gandhi
Publikováno v:
Blood. 140:3865-3867
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deb3f2b2d4842bc451d82e70336b717c
https://doi.org/10.1182/blood-2022-166407
https://doi.org/10.1182/blood-2022-166407
Publikováno v:
Free Radic Biol Med
Nitric oxide (NO) binds to soluble guanylyl cyclase (GC1) and stimulates its catalytic activity to produce cGMP. Despite the key role of the NO-cGMP signaling in cardiovascular physiology, the mechanisms of GC1 activation remain ill-defined. It is be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07181d3b2a9030662ae3b064f2429a9
https://doi.org/10.1016/j.freeradbiomed.2020.11.001
https://doi.org/10.1016/j.freeradbiomed.2020.11.001
Autor:
Danny V Jeyaraju, Maryam Alapa, Aimee O'Donohue, Ross La Motte-Mohs, Isaac W. Boss, Patrick Hagner, Michael Pourdehnad, Michael R. Burgess, William E. Pierceall, Anjan Thakurta
Publikováno v:
Blood. 140:7070-7071
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e701a1a20137e965cb14f0ba51773e4
https://doi.org/10.1182/blood-2022-157927
https://doi.org/10.1182/blood-2022-157927
Autor:
Jammula Sriganesh, Charalampos Kyriakopoulos, Patrick Hagner, Alberto Risueño, Gaurav Jain, Danny V Jeyaraju, Anjan Thakurta, Amit Anand, Daniel Menezes, Christopher Hartl, Aarif Ahsan, Chao Wang, Madhusudhan Reddy, Maryam Alapa, Nathalie Lailler, Prakash Subramanyam, Ann Polonskaia, Kaushik Ghosh
Publikováno v:
Blood. 138:3355-3355
Acute Myeloid Leukemia (AML) is characterized by uncontrolled proliferation of incompletely differentiated myeloid stem/ progenitor cells. Despite recent advances in therapy, high rates of clinical relapse, even in patients who achieve complete remis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3125c97cac5c9ad90cc12e0041298ef
https://doi.org/10.1182/blood-2021-153523
https://doi.org/10.1182/blood-2021-153523
Autor:
Vladyslav Kholodovych, Maryam Alapa, Can Huang, Changgong Wu, Junichi Sadoshima, Narayani Nagarajan, Annie Beuve, Hong Li, Ping Shu
Publikováno v:
Journal of Biological Chemistry. 292:14362-14370
Nitric oxide (NO) modulates many physiological events through production of cGMP from its receptor, the NO-sensitive guanylyl cyclase (GC1). NO also appears to function in a cGMP-independent manner, via S-nitrosation (SNO), a redox-based modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7cea942be2619c604fdde80c2887f3
https://doi.org/10.1074/jbc.m117.787390
https://doi.org/10.1074/jbc.m117.787390
Publikováno v:
Circulation Research. 125
Soluble guanylyl cyclase (GC1) is the major receptor of nitric oxide (NO) and a key regulator for cardiovascular physiology. NO binding to the heme of GC1 catalyzes conversion of GTP to cGMP, which in turn activates protein kinase G pathway, thus lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbabd6a999498df84debc24316122db5
https://doi.org/10.1161/res.125.suppl_1.869
https://doi.org/10.1161/res.125.suppl_1.869