Výsledky vyhledávání - "Maryalice Stetler-Stevenson"

Akademický článek

Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22

Autor: Haiying Qin, Sneha Ramakrishna, Sang Nguyen, Thomas J. Fountaine, Anusha Ponduri, Maryalice Stetler-Stevenson, Constance M. Yuan, Waleed Haso, Jack F. Shern, Nirali N. Shah, Terry J. Fry

Publikováno v: Molecular Therapy: Oncolytics, Vol 11, Iss , Pp 127-137 (2018)

Despite high remission rates following CAR-T cell therapy in B-ALL, relapse due to loss of the targeted antigen is increasingly recognized as a mechanism of immune escape. We hypothesized that simultaneous targeting of CD19 and CD22 may reduce the li

Externí odkaz: https://doaj.org/article/d882270e82e3424288a0765b0e98678d

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Akademický článek

Expression of the muscle-associated gene MYF6 in hairy cell leukemia.

Autor: Evgeny Arons, Hong Zhou, Mark Sokolsky, Daniel Gorelik, Katherine Potocka, Sarah Davies, Erin Fykes, Katherine Still, Daniel C Edelman, Yonghong Wang, Paul S Meltzer, Mark Raffeld, Adrian Wiestner, Liqiang Xi, Hao-Wei Wang, Maryalice Stetler-Stevenson, Constance Yuan, Robert J Kreitman

Publikováno v: PLoS ONE, Vol 15, Iss 2, p e0227586 (2020)

Hairy cell leukemia (HCL) is a purine analog-responsive B-cell malignancy containing the BRAF V600E mutation, expressing CD22, CD11c, CD103, tartrate resistant acid phosphatase (TRAP) CD25, CD123, and annexin 1A. BRAF V600E and the latter 4 markers a

Externí odkaz: https://doaj.org/article/b4c3619133ba44569ecd584f874b3177

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Akademický článek

Baseline mutational patterns and sustained MRD negativity in patients with high-risk smoldering myeloma

Publikováno v: Blood Advances, Vol 1, Iss 22, Pp 1911-1918 (2017)

Abstract: Early results of a prospective phase 2 clinical trial of carfilzomib, lenalidomide, and dexamethasone followed by lenalidomide maintenance in high-risk smoldering myeloma showed promising results that were previously published. Here, we pro

Externí odkaz: https://doaj.org/article/e1f11c1f135a476c97b54d61c9bd3dfc

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Akademický článek

Detection and outcome of occult leptomeningeal disease in diffuse large B-cell lymphoma and Burkitt lymphoma

Publikováno v: Haematologica, Vol 99, Iss 7 (2014)

The benefit of intrathecal therapy and systemic rituximab on the outcome of diffuse large B-cell lymphoma at risk of central nervous system disease is controversial. Furthermore, the effect of intrathecal treatment and rituximab in diffuse large B-ce

Externí odkaz: https://doaj.org/article/fba07b66f6344a6cad1da8ca8852d8cc

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Akademický článek

Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications

Autor: Katherine R. Calvo, Donald C. Vinh, Irina Maric, Weixin Wang, Pierre Noel, Maryalice Stetler-Stevenson, Diane C. Arthur, Mark Raffeld, Amalia Dutra, Evgenia Pak, Kyungjae Myung, Amy P. Hsu, Dennis D. Hickstein, Stefania Pittaluga, Steven M. Holland

Publikováno v: Haematologica, Vol 96, Iss 8 (2011)

A novel, genetic immunodeficiency syndrome has been recently described, herein termed “MonoMAC”. It is characterized by severe circulating monocytopenia, NK- and B-lymphocytopenia, severe infections with M. avium complex (MAC), and risk of progre

Externí odkaz: https://doaj.org/article/355eb7e76b084cc0a550b32607fa7142

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