Zobrazeno 1 - 2
of 2
pro vyhledávání: '"MaryJean Pendleton"'
Publikováno v:
Annals of the New York Academy of Sciences. 1310:98-110
Type II topoisomerases are essential enzymes that modulate DNA under- and overwinding, knotting, and tangling. Beyond their critical physiological functions, these enzymes are the targets for some of the most widely prescribed anticancer drugs (topoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7df8eb000a160fbab7761973b5e754
https://doi.org/10.1111/nyas.12358
https://doi.org/10.1111/nyas.12358
Autor:
Joseph E. Deweese, Rachel E. Ashley, MaryJean Pendleton, Susan L. Mercer, R. Hunter Lindsey, Neil Osheroff
Publikováno v:
Biochemistry
Coordination between the N-terminal gate and the catalytic core of topoisomerase II allows the proper capture, cleavage, and transport of DNA during the catalytic cycle. Because the activities of these domains are tightly linked, it has been difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc0b7143d5d0ffc73c8903749084727
https://pubmed.ncbi.nlm.nih.gov/25280269
https://pubmed.ncbi.nlm.nih.gov/25280269