Zobrazeno 1 - 10
of 19
pro vyhledávání: '"MaryClare F. Rollins"'
Autor:
Jerod A Skyberg, MaryClare F Rollins, Jeff S Holderness, Nicole L Marlenee, Igor A Schepetkin, Andrew Goodyear, Steven W Dow, Mark A Jutila, David W Pascual
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002587 (2012)
Pulmonary Francisella tularensis and Burkholderia pseudomallei infections are highly lethal in untreated patients, and current antibiotic regimens are not always effective. Activating the innate immune system provides an alternative means of treating
Externí odkaz:
https://doaj.org/article/b8692fcb917c4ee88c2be4ab0fc4c531
Autor:
Elena S Suvorova, Olivier Lucas, Carla M Weisend, Maryclare F Rollins, Gary F Merrill, Mario R Capecchi, Edward E Schmidt
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6158 (2009)
Metabolically active cells require robust mechanisms to combat oxidative stress. The cytoplasmic thioredoxin reductase/thioredoxin (Txnrd1/Txn1) system maintains reduced protein dithiols and provides electrons to some cellular reductases, including p
Externí odkaz:
https://doaj.org/article/ec3c731591a74773bdc7a1ebf0e61378
Autor:
Saikat Chowdhury, Blake Wiedenheft, Heini M. Miettinen, Andrew Santiago-Frangos, C. Martin Lawrence, Dominick Faith, Joshua Carter, Gabriel C. Lander, Sarah Golden, MaryClare F. Rollins
Bacteria and archaea have evolved sophisticated adaptive immune systems that rely on CRISPR RNA (crRNA)-guided detection and nuclease-mediated elimination of invading nucleic acids. Here we present the cryo-EM structure of the type I-F CRISPR RNA-gui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8588a0f3439359e317bad2612663307
https://doi.org/10.1101/453720
https://doi.org/10.1101/453720
Autor:
C. Martin Lawrence, Saikat Chowdhury, Sarah Golden, MaryClare F. Rollins, Gabriel C. Lander, Andrew Santiago-Frangos, Dominick Faith, Blake Wiedenheft, Joshua Carter, Heini M. Miettinen
Publikováno v:
Molecular cell. 74(1)
Summary Bacteria and archaea have evolved sophisticated adaptive immune systems that rely on CRISPR RNA (crRNA)-guided detection and nuclease-mediated elimination of invading nucleic acids. Here, we present the cryo-electron microscopy (cryo-EM) stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34f42095ab21a927a7458a9f0420de9
https://pubmed.ncbi.nlm.nih.gov/30872121
https://pubmed.ncbi.nlm.nih.gov/30872121
Autor:
Joseph Bondy-Denomy, Adair L. Borges, Beatriz A. Osuna, Blake Wiedenheft, MaryClare F. Rollins, Jenny Y. Zhang
Publikováno v:
Cell, vol 174, iss 4
SUMMARY>Bacteria utilize CRISPR-Cas adaptive immune systems for protection from bacteriophages (phages), and some phages produce anti-CRISPR (Acr) proteins that inhibit immune function. Despite thorough mechanistic and structural information for some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b9986499b197b24e3650fae3182f2a
https://europepmc.org/articles/PMC6086726/
https://europepmc.org/articles/PMC6086726/
Autor:
Mingjian Du, Joseph Bondy-Denomy, Blake Wiedenheft, Alan R. Davidson, Bianca Garcia, Karen L. Maxwell, Scott Strum, MaryClare F. Rollins, Yurima Hidalgo-Reyes
Publikováno v:
Nature. 526:136-139
The battle for survival between bacteria and the viruses that infect them (phages) has led to the evolution of many bacterial defence systems and phage-encoded antagonists of these systems. Clustered regularly interspaced short palindromic repeats (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc018693ddaabe2b3b9f79121c12e9ca
https://doi.org/10.1038/nature15254
https://doi.org/10.1038/nature15254
Publikováno v:
Nucleic Acids Research
The Type I-F CRISPR-mediated (clustered regularly interspaced short palindromic repeats) adaptive immune system in Pseudomonas aeruginosa consists of two CRISPR loci and six CRISPR-associated (cas) genes. Foreign DNA surveillance is performed by a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a596be267826638ef8174b7dfe7abd9
http://doc.rero.ch/record/299651/files/gkv094.pdf
http://doc.rero.ch/record/299651/files/gkv094.pdf
Autor:
Joshua Carter, Saikat Chowdhury, MaryClare F. Rollins, Blake Wiedenheft, Royce A. Wilkinson, Sarah Golden, Gabriel C. Lander, Joseph Bondy-Denomy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 26
The type I-F CRISPR adaptive immune system in Pseudomonas aeruginosa (PA14) consists of two CRISPR loci and six CRISPR-associated (cas) genes. Type I-F systems rely on a CRISPR RNA (crRNA)-guided surveillance complex (Csy complex) to bind foreign DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00452d6190a3f1fea3ed89c6665b2953
https://escholarship.org/uc/item/8ts855d5
https://escholarship.org/uc/item/8ts855d5
Autor:
Marjorie D. Sutherland, David W. Pascual, John T. Belisle, Jerod A. Skyberg, MaryClare F. Rollins, Joshua W. Samuel
Publikováno v:
Infection and Immunity. 81:3099-3105
Francisella tularensis is a highly infectious intracellular bacterium that causes the zoonotic infection tularemia. While much literature exists on the host response to F. tularensis infection, the vast majority of work has been conducted using atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08d80fc0dc1c8d6cd49d5793fa6d8f5
https://doi.org/10.1128/iai.00203-13
https://doi.org/10.1128/iai.00203-13
Autor:
Ryan N. Jackson, Blake Wiedenheft, MaryClare F. Rollins, Joshua Carter, Gabriel C. Lander, Saikat Chowdhury, Lyn‘Al Nosaka
Publikováno v:
Biophysical Journal. 112:334a-335a
Bacteria and archaea have evolved different CRISPR based adaptive immune system for defense against phage infections. Pseudomonas aeruginosa has type I-F CRISPR-cas defense system, where the cas-crRNA surveillance complex (csy-complex) binds to forei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ffa1927c385dd810e9a1c6f450c099
https://doi.org/10.1016/j.bpj.2016.11.1811
https://doi.org/10.1016/j.bpj.2016.11.1811