Zobrazeno 1 - 10
of 13
pro vyhledávání: '"MaryAnn Mahajan"'
Autor:
Peter H. Tang, Teja Chemudupati, Katherine J. Wert, James C. Folk, MaryAnn Mahajan, Stephen H. Tsang, Alexander G. Bassuk, Vinit B. Mahajan
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 18, Iss , Pp - (2020)
Purpose: To characterize the phenotype of patients with mild calpain-5 Neovascular Inflammatory Vitreoretinopathy (ADNIV). Observations: The CAPN5 p.R243L mutation is typically associated with onset in the twenties and severe, progressive uveitis, re
Externí odkaz:
https://doaj.org/article/90850f472e4449889b0e96e2762b3c4a
Autor:
Kellie Schaefer, MaryAnn Mahajan, Anuradha Gore, Stephen H. Tsang, Alexander G. Bassuk, Vinit B. Mahajan
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Objective Our objective was to characterize CAPN5 gene expression in the mouse central nervous system. Mouse brain and eye sections were probed with two high-affinity RNA oligonucleotide analogs designed to bind CAPN5 RNA and one scramble, c
Externí odkaz:
https://doaj.org/article/e69ae889ec754b98b9b738d059cb97a6
Autor:
MaryAnn Mahajan, Stephen H. Tsang, James C. Folk, Peter H Tang, Tyson R. Kinnick, Vinit B. Mahajan, Alexander G. Bassuk
Publikováno v:
Retin Cases Brief Rep
Characterization of the degradation of scotopic electroretinography recordings from patients in various stages of ADNIV reveal photoreceptors may sustain early insult and reveals a unique time frame for potential therapeutic intervention. PURPOSE: To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9ba50e81c46a4e62c0f40ccd39e77f
https://doi.org/10.1097/icb.0000000000000828
https://doi.org/10.1097/icb.0000000000000828
Autor:
Elizabeth A. Newell, Jolonda C. Mahoney, Alexander G. Bassuk, Lucy P. Evans, Christopher Donald Hue, Russell Nichols, Edward W. Vogel, Barclay Morrison, Polly J. Ferguson, MaryAnn Mahajan, Vinit B. Mahajan, Ottavio Arancio, Stephen H. Tsang
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Limited attention has been given to ocular injuries associated with traumatic brain injury (TBI). The retina is an extension of the central nervous system and evaluation of ocular damage may offer a less‐invasive approach to gauge TBI sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041dee90bdfab62599c1cc39d50d6bab
http://europepmc.org/articles/PMC5846452
http://europepmc.org/articles/PMC5846452
Autor:
MaryAnn Mahajan, Vinit B. Mahajan, Janet R. Sparrow, Yi-Ting Tsai, Anuradha Gore, Chun-Wei Hsu, Alexander G. Bassuk, Stephen H. Tsang, Ronald H. Silverman, Gabriel Velez, Aliaa H Abdelhakim
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
Hyperopia (farsightedness) is a common and significant cause of visual impairment, and extreme hyperopia (nanophthalmos) is a consequence of loss-of-function MFRP mutations. MFRP deficiency causes abnormal eye growth along the visual axis and signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11758a91a16909f0f1b9e0ddf1a59d8b
http://link.springer.com/article/10.1038/s41598-017-16275-8
http://link.springer.com/article/10.1038/s41598-017-16275-8
Autor:
Katherine J. Wert, Susanne F. Koch, Gabriel Velez, Chun‐Wei Hsu, MaryAnn Mahajan, Alexander G. Bassuk, Stephen H. Tsang, Vinit B. Mahajan
Publikováno v:
Human Mutation. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c7f8dc849f1193eac6549de39efdef
https://doi.org/10.1002/humu.23958
https://doi.org/10.1002/humu.23958
Autor:
Gabriel, Velez, Alexander G, Bassuk, Kellie A, Schaefer, Brian, Brooks, Lokesh, Gakhar, MaryAnn, Mahajan, Philip, Kahn, Stephen H, Tsang, Polly J, Ferguson, Vinit B, Mahajan
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Mutations that activate the protease calpain-5 (CAPN5) cause a nonsyndromic adult-onset autoinflammatory eye disease characterized by uveitis, altered synaptic signaling, retinal degeneration, neovascularization, and intraocular fibrosis. We describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddd8ba34a58adf68d7a6edeea08fb883
https://pubmed.ncbi.nlm.nih.gov/29472286
https://pubmed.ncbi.nlm.nih.gov/29472286
Autor:
Marcus A. Toral, MaryAnn Mahajan, Thiago Cabral, Vinit B. Mahajan, James E. DiCarlo, Gabriel Velez, Anuradha Gore, Alexander G. Bassuk, Stephen H. Tsang
Publikováno v:
Journal of Visualized Experiments.
The human retina is composed of the sensory neuroretina and the underlying retinal pigmented epithelium (RPE), which is firmly complexed to the vascular choroid layer. Different regions of the retina are anatomically and molecularly distinct, facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bb40de4fabf0fc25b979e723142bdd
https://doi.org/10.3791/56203
https://doi.org/10.3791/56203
Autor:
Alexander G. Bassuk, Stephen H. Tsang, Kellie A. Schaefer, MaryAnn Mahajan, Anuradha Gore, Vinit B. Mahajan
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Our objective was to characterize CAPN5 gene expression in the mouse central nervous system. Mouse brain and eye sections were probed with two high-affinity RNA oligonucleotide analogs designed to bind CAPN5 RNA and one scramble, control oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e68b03ad592fef36420c881c22c14c
https://pubmed.ncbi.nlm.nih.gov/29157313
https://pubmed.ncbi.nlm.nih.gov/29157313
Autor:
Joaquin Tosi, Maria B. Grant, Yuanqing Yan, Lijuan Zhang, Stephen H. Tsang, Kerstin M. Janisch, Chun Wei Hsu, MaryAnn Mahajan, Katherine J. Wert, Vinit B. Mahajan, Alexander G. Bassuk, Takayuki Nagasaki, Yao Li
Publikováno v:
Signal Transduction and Targeted Therapy
Diabetic retinopathy (DR) affects approximately one-third of diabetic patients and, if left untreated, progresses to proliferative DR (PDR) with associated vitreous hemorrhage, retinal detachment, iris neovascularization, glaucoma and irreversible bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910bc5920d45a4fa5befaac6be98d6f2
https://pubmed.ncbi.nlm.nih.gov/27195131
https://pubmed.ncbi.nlm.nih.gov/27195131