Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mary-Louise Wilde"'
Autor:
Mary-Louise Wilde, Tony Triglia, Danushka Marapana, Jennifer K. Thompson, Alexei A. Kouzmitchev, Hayley E. Bullen, Paul R. Gilson, Alan F. Cowman, Christopher J. Tonkin
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Understanding the mechanisms behind host cell invasion by Plasmodium falciparum remains a major hurdle to developing antimalarial therapeutics that target the asexual cycle and the symptomatic stage of malaria. Host cell entry is enabled by
Externí odkaz:
https://doaj.org/article/e57a13863f35463ca89cb2fe9e8b1b58
Autor:
Alessandro D Uboldi, Mary-Louise Wilde, Emi A McRae, Rebecca J Stewart, Laura F Dagley, Luning Yang, Nicholas J Katris, Sanduni V Hapuarachchi, Michael J Coffey, Adele M Lehane, Cyrille Y Botte, Ross F Waller, Andrew I Webb, Malcolm J McConville, Christopher J Tonkin
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005642 (2018)
The phylum Apicomplexa comprises a group of obligate intracellular parasites that alternate between intracellular replicating stages and actively motile extracellular forms that move through tissue. Parasite cytosolic Ca2+ signalling activates motili
Externí odkaz:
https://doaj.org/article/b74ca0993f11485cab44baf31f1908a9
Autor:
Mary-Louise Wilde, Ushma Ruparel, Theresa Klemm, V Vern Lee, Dale J Calleja, David Komander, Christopher J Tonkin
Publikováno v:
Life Science Alliance. 6:e202201710
The phylum Apicomplexa contains several parasitic species of medical and agricultural importance. The ubiquitination machinery remains, for the most part, uncharacterised in apicomplexan parasites, despite the important roles that it plays in eukaryo
Autor:
Lilach Sheiner, Jeremy G. Wideman, Christopher J. Tonkin, Marco Biddau, Jana Ovciarikova, Clare R. Harding, Erica S. Martins-Duarte, Alessandro D. Uboldi, Natalia Mallo, Mary-Louise Wilde, Stephan C Baehr, Leandro Lemgruber
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The voltage-dependent anion channel (VDAC) is a ubiquitous channel in the outer membrane of the mitochondrion with multiple roles in protein, metabolite and small molecule transport. In mammalian cells, VDAC protein, as part of a larger complex inclu
Publikováno v:
Molecular microbiologyReferences. 115(5)
Toxoplasma and other apicomplexan parasites undergo a unique form of cellular locomotion referred to as "gliding motility." Gliding motility is crucial for parasite survival as it powers tissue dissemination, host cell invasion and egress. Distinct e
Autor:
Natalia Mallo, Christopher J. Tonkin, Jana Ovciarikova, Erica S dos Santos Martins Duarte, Lilach Sheiner, Jeremy G. Wideman, Alessandro D. Uboldi, Leandro Lemgruber, Stephan C Baehr, Mary-Louise Wilde, Clare R. Harding, Marco Biddau
The Voltage Dependent Anion channel (VDAC) is a ubiquitous channel in the outer membrane of the mitochondrion with multiple roles in protein, metabolite and small molecule transport. In mammalian cells, VDAC, as part of a larger complex including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::955ddd7a00675309ba383eb1b585ca32
https://doi.org/10.1101/2020.10.07.330423
https://doi.org/10.1101/2020.10.07.330423
Autor:
Paul R. Gilson, Mary-Louise Wilde, Jennifer K. Thompson, Alan F. Cowman, Christopher J. Tonkin, Hayley E Bullen, Danushka S. Marapana, Alexei A Kouzmitchev, Tony Triglia
Publikováno v:
mBio, Vol 10, Iss 5, p e01972-19 (2019)
mBio
mBio, Vol 10, Iss 5 (2019)
mBio
mBio, Vol 10, Iss 5 (2019)
Malaria continues to present a major global health burden, particularly in low-resource countries. Plasmodium falciparum, the parasite responsible for the most severe form of malaria, causes disease through rapid and repeated rounds of invasion and r
Autor:
Alessandro D. Uboldi, Malcolm J. McConville, Luning Yang, Rebecca Stewart, Mary Louise Wilde, Simona Seizova, Martina Kocan, Cyrille Y. Botté, Yoshiki Yamaryo-Botté, Ross A. D. Bathgate, Philip E. Thompson, Nicholas J. Katris, Michael J Coffey, Christopher J. Tonkin
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (22), pp.8959-8972. ⟨10.1074/jbc.RA118.005491⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (22), pp.8959-8972. ⟨10.1074/jbc.RA118.005491⟩
International audience; Protozoan parasites of the phylum Apicomplexa actively move through tissue to initiate and perpetuate infection. The regulation of parasite motility relies on cyclic nucleotide-dependent kinases, but how these kinases are acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab97c95a3306200562537bbed3087df
https://hal.archives-ouvertes.fr/hal-02415218
https://hal.archives-ouvertes.fr/hal-02415218
Autor:
Rebecca Stewart, Laura F. Dagley, Sanduni V. Hapuarachchi, Malcolm J. McConville, Cyrille Y. Botté, Alessandro D. Uboldi, Luning Yang, Nicholas J. Katris, Ross F. Waller, Adele M. Lehane, Christopher J. Tonkin, Michael J Coffey, Mary-Louise Wilde, Emi A. McRae, Andrew I. Webb
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2018, 16 (9), pp.e2005642. ⟨10.1371/journal.pbio.2005642⟩
PLoS Biology, Vol 16, Iss 9, p e2005642 (2018)
PLoS Biology, 2018, 16 (9), pp.e2005642. ⟨10.1371/journal.pbio.2005642⟩
PLoS Biology, Public Library of Science, 2018, 16 (9), pp.e2005642. ⟨10.1371/journal.pbio.2005642⟩
PLoS Biology, Vol 16, Iss 9, p e2005642 (2018)
PLoS Biology, 2018, 16 (9), pp.e2005642. ⟨10.1371/journal.pbio.2005642⟩
The phylum Apicomplexa comprises a group of obligate intracellular parasites that alternate between intracellular replicating stages and actively motile extracellular forms that move through tissue. Parasite cytosolic Ca2+ signalling activates motili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ba262a42a186d9210241c1794159a6
https://www.hal.inserm.fr/inserm-02139070
https://www.hal.inserm.fr/inserm-02139070
Autor:
Luning, Yang, Alessandro D, Uboldi, Simona, Seizova, Mary-Louise, Wilde, Michael J, Coffey, Nicholas J, Katris, Yoshiki, Yamaryo-Botté, Martina, Kocan, Ross A D, Bathgate, Rebecca J, Stewart, Malcolm J, McConville, Philip E, Thompson, Cyrille Y, Botté, Christopher J, Tonkin
Publikováno v:
J Biol Chem
Protozoan parasites of the phylum Apicomplexa actively move through tissue to initiate and perpetuate infection. The regulation of parasite motility relies on cyclic nucleotide-dependent kinases, but how these kinases are activated remains unknown. H