Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mary-Jo Miller"'
Autor:
Eckhardt S. Ferdinandi, Larry S. Andrews, John J. Kneiss, Mark Klan, J. Fielding Douglas, Mary Jo Miller
Publikováno v:
Journal of Applied Toxicology. 17:S3-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::191ecdc8760638fd980a156800703bcc
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+3.0.co
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+
Autor:
Eckhardt S. Ferdinandi, Larry S. Andrews, Mark Klan, John J. Kneiss, J. Fielding Douglas, Mary Jo Miller
Publikováno v:
Journal of Applied Toxicology. 17:S3-S12
Methyl t-butyl ether (MTBE) is a commonly used octane booster in gasoline. This study examines the pharmacokinetics and disposition of MTBE in Fischer-344 rats after i.v., oral, dermal and inhalation routes of administration. Groups of male and femal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd985d0010137f8e0f16650a6a83a10
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+3.3.co
https://doi.org/10.1002/(sici)1099-1263(199705)17:1+
Autor:
Winnie Lee, Gerhard Koenig, Mary Jo Miller, Zhiyong Yang, Hilliary Hodgdon, Daniel Havas, Emily A. Freeman, Veerle Vulsteke, Holger Patzke, Liza Leventhal, Richard Chesworth, Sarah C. Hopp, Faris Albayya, Jean Francois Blain, Zhiming Tu, Michael K. Ahlijanian, Lori Hrdlicka, Louise Scrocchi, Scott Nolan, Melody Wen, Henrik Zetterberg, Dorothy G. Flood, Don Costa, Kevin M. Felsenstein, Erik Portelius, Kathryn Rogers, Gideon Shapiro, Birgit Hutter-Paier, Bart De Strooper, Darcie Spaulding
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 61 (2012)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background A hallmark of Alzheimer’s disease is the presence of senile plaques in human brain primarily containing the amyloid peptides Aβ42 and Aβ40. Many drug discovery efforts have focused on decreasing the production of Aβ42 through γ-secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455a88ecbc048653eaeb4fe42e5c0f15
http://www.molecularneurodegeneration.com/content/7/1/61
http://www.molecularneurodegeneration.com/content/7/1/61
Publikováno v:
International journal of toxicology. 31(2)
Female F344 rats were fed diets containing 0.02%, 0.2%, or 2.0% white mineral oil for 90 days. There were no gross or microscopic differences in target organs at the 0.02% level. In the higher-dose groups, relative liver and mesenteric lymph node (ML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1843f3c012de96dfd21c94e20436f3f
https://pubmed.ncbi.nlm.nih.gov/22422433
https://pubmed.ncbi.nlm.nih.gov/22422433
Autor:
Florentina Catana, Michael K. Ahlijanian, Gerhard Koenig, Thomas Koperniak, Don Costa, Kathryn Rogers, Liza Leventhal, Darcie Spaulding, Mary-Jo Miller, Scott Nolan, Hilliary Hodgdon, Kevin M. Felsenstein, Zhiyong Yang, Lori Hrdlicka, Richard Chesworth, Gideon Shapiro, Winnie Lee, Melody Wen, Sarah C. Hopp
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77adba42ad74699028513476ded43b67
https://doi.org/10.1016/j.jalz.2010.08.082
https://doi.org/10.1016/j.jalz.2010.08.082
Publikováno v:
Critical Reviews in Oral Biology & Medicine. 1:261-281
This summarizes current knowledge of the benefits and risks of fluoride ingestion. The preponderance of evidence indicates that fluoride can reduce the incidence of dental caries and that fluoridation of drinking water can provide such protection. Du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f3e25a62f14892c02d1303e654bb60
https://doi.org/10.1177/10454411900010040501
https://doi.org/10.1177/10454411900010040501
Autor:
Mary Jo Miller, Charlene A. McQueen
Publikováno v:
Environmental Mutagenesis. 8:99-108
Acrylamide has recently been reported to induce tumors in laboratory animals. The effect of acrylamide on unscheduled DNA synthesis using the hepatocyte primary culture (HPC)/DNA repair test was examined. Isolated hepatocytes were exposed to acrylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4d302695147a262cd4feb4f1c2ea12
https://doi.org/10.1002/em.2860080109
https://doi.org/10.1002/em.2860080109
Autor:
Charlene A. McQueen, Mary Jo Miller
Publikováno v:
Analytical Biochemistry. 153:39-44
A high-pressure liquid chromatography method was developed to separate 2-aminofluorene and several ring-hydroxylated metabolites. The acetylated derivatives of these compounds and N-hydroxy-2-acetylaminofluorene were also separated simultaneously. HP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638a64e8495b2e62d729b50ac307cbcd
https://doi.org/10.1016/0003-2697(86)90057-6
https://doi.org/10.1016/0003-2697(86)90057-6
Publikováno v:
Chemico-biological interactions. 66(1-2)
N-acetylation is involved in determining species susceptibility to carcinogenicity by certain aromatic amines. In order to further investigate this relationship, the biotransformation of 2-aminofluorene (2-AF) by monolayer cultures of hepatocytes iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd56830d4961db26c303ccdaef447edd
https://pubmed.ncbi.nlm.nih.gov/3383289
https://pubmed.ncbi.nlm.nih.gov/3383289
Publikováno v:
Cell biology and toxicology. 2(2)
Sex-related differences in susceptibility to 2-acetylaminofluorene (2-AAF) hepatocarcinogenicity and in vivo biotransformation of 2-AAF have been observed. In order to determine the contribution of hepatocytes to these differences, 2-AAF biotransform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19635877b96e3507ac6e8281617cde01
https://pubmed.ncbi.nlm.nih.gov/3267451
https://pubmed.ncbi.nlm.nih.gov/3267451