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pro vyhledávání: '"Mary-Ann Efthivoulou"'
Autor:
Mary-Ann Efthivoulou, Michael N. Berry
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:267-274
The addition of antipyrine or aminopyrine to isolated hepatocytes derived from normal rats and incubated with ethanol caused a significant decrease in the oxidation of ethanol to acetate. This decrease was associated with a corresponding accumulation
Autor:
Mary-Ann Efthivoulou, Michael N. Berry
Publikováno v:
Biochemical Pharmacology. 52:863-867
The addition of aniline to isolated hepatocytes derived from fasted rats and incubated with ethanol, caused a 30-60% decrease in the rate of ethanol oxidation. The degree of inhibition was dependent on aniline concentration, 5 mM causing near-maximal
Publikováno v:
Biochimica et biophysica acta. 1244(2-3)
When isolated hepatocytes from fasted rats were incubated with 10 mM lactate, the [lactate]/[pyruvate] ratio measured at the beginning of the incubation was raised above 70:1 but declined to a steady level of about 8:1 within 40 min. The rate of gluc