Výsledky vyhledávání - "Mary Y. Stovall"

Neutrophils enhance clearance of necrotic epithelial cells in ozone-induced lung injury in rhesus monkeys

Autor: Robert Rothlein, Ruth J. McDonald, Dallas M. Hyde, Charles G. Plopper, Craig D. Wegner, Viviana Wong, Kent E. Pinkerton, Lisa A. Miller, Mary Y. Stovall

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 277:L1190-L1198

To test the hypothesis that neutrophil influx is important for the removal of necrotic airway epithelial cells, rhesus monkeys were treated with a function-blocking monoclonal antibody (MAb) against CD18 followed by exposure to ozone or filtered air.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1415a4a64d43cff77e9fdf2df3ce117d
https://doi.org/10.1152/ajplung.1999.277.6.l1190

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Cutting Edge: Protective Response to Pulmonary Injury Requires γδ T Lymphocytes

Autor: Donald P. King, Dallas M. Hyde, Kenneth A. Jackson, Denise M. Novosad, Terri N. Ellis, Lei Putney, Mary Y. Stovall, Laura S. Van Winkle, Blaine L. Beaman, David A. Ferrick

Publikováno v: The Journal of Immunology. 162:5033-5036

γδ intraepithelial lymphocytes are thought to coordinate responses to pathogens that penetrate the epithelial barrier. To directly test this, mice were inoculated with Nocardia asteroides. At doses that were nonlethal for control mice, γδ-deficie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbcc47f167947dd30d5295b06a4eb29b
https://doi.org/10.4049/jimmunol.162.9.5033

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Breathing Pattern Response and Epithelial Labeling in Ozone-Induced Airway Injury in Neutrophil-Depleted Rats

Autor: Jack R. Harkema, Edward S. Schelegle, Dallas M. Hyde, Keith R. Vesely, Mary Y. Stovall, J. F. Green

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 20:699-709

To test the hypothesis that neutrophils enhance the repair of ozone (O3)-injured airway epithelium, we investigated breathing pattern responses and airway epithelial injury and repair in rats depleted of neutrophils using rabbit antirat neutrophil se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cec5eacfda75bc543f91eb1d4e5892
https://doi.org/10.1165/ajrcmb.20.4.3362

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Repeated episodes of C5a-induced neutrophil influx do not result in pulmonary fibrosis

Autor: Mary Y. Stovall, Shiri N. Giri, Qingjian Wang, Dallas M. Hyde, Jane A. Harris

Publikováno v: Inflammation. 15:233-250

Multiple reactive oxygen species-induced epithelial injury by glucose, glucose oxidase, and lactoperoxidase instillation in the lung results in a progressive interstitial fibrosis. To test the hypothesis that multiple pulmonary inflammatory responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112428173f08a43e74e2274a5e21f86a
https://doi.org/10.1007/bf00918649

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Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys

Autor: Leialoha F. Putney, Mary Y. Stovall, Laurel J. Gershwin, Dallas M. Hyde, Edward S. Schelegle, Charles G. Plopper, Robert L. Coffman, Debbie L. Chou, Lisa A. Miller, S. D. Hurst, Nancy K. Tyler

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 35(7)

Summary Background Accumulation of immune cell populations and their cytokine products within tracheobronchial airways contributes to the pathogenesis of allergic asthma. It has been postulated that peripheral regions of the lung play a more signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6cfc8405650f04e41d1351bce9f865
https://pubmed.ncbi.nlm.nih.gov/16008676

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Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats

Autor: Edward S. Schelegle, Mary Y. Stovall, Leialoha F. Putney, Nancy K. Tyler, Dallas M. Hyde, Mario F. Alfaro

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 91(4)

We examined the relationship between C-fiber-mediated, ozone-induced rapid shallow breathing and airway epithelial cell injury at different airway sites within the lower respiratory tract of conscious Wistar rats ( n = 24). We combined an acute 8-h o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740cf517227638f4a3c3390a0f913665
https://pubmed.ncbi.nlm.nih.gov/11568142

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Neonatal capsaicin treatment increases the severity of ozone-induced lung injury

Autor: Mary Y. Stovall, J. F. Green, Edward S. Schelegle, A. Sterner-Kock, Keith R. Vesely, Dallas M. Hyde

Publikováno v: American journal of respiratory and critical care medicine. 153(1)

To test the hypothesis that lung sensory C fibers protect the small distal airways and alveoli from oxidant injury, we compared the effects of inhalation of ozone (1 ppm) or filtered air for 8 h on lung injury and lung inflammation in four groups of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37288ddaf11fe966e64c31b2a91e2d20
https://pubmed.ncbi.nlm.nih.gov/8542155

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Acute ozone-induced lung injury in neutrophil-depleted rats

Autor: Michael V. Pino, Dallas M. Hyde, Robert B. Devlin, Hillel S. Koren, Jana R. Levin, Mary Y. Stovall

Publikováno v: Toxicology and applied pharmacology. 114(2)

To test the hypothesis that neutrophils contribute to acute, ozone-induced epithelial damage in the lung, rats were depleted of their circulating neutrophils by intraperitoneal injection of a rabbit anti-rat neutrophil serum (ANS) 12 hr prior to an 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00c2f018fa8f90d61e9d30bdee8af02
https://pubmed.ncbi.nlm.nih.gov/1609419

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