Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mary X O'Riordan"'
Autor:
Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Gautam J Sule, Jason S Knight, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan, Basel H Abuaita
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010855 (2022)
Infection of the human gut by Salmonella enterica Typhimurium (STM) results in a localized inflammatory disease that is not mimicked in murine infections. To determine mechanisms by which neutrophils, as early responders to bacterial challenge, direc
Externí odkaz:
https://doaj.org/article/bc7475739de7493a804ae366c621795c
Autor:
Basel H Abuaita, Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009987 (2021)
Salmonella enterica represents over 2500 serovars associated with a wide-ranging spectrum of disease; from self-limiting gastroenteritis to invasive infections caused by non-typhoidal serovars (NTS) and typhoidal serovars, respectively. Host factors
Externí odkaz:
https://doaj.org/article/dd451e9f855f4a058b08f270822eb9ab
Autor:
Mack B. Reynolds, Benjamin Klein, Michael J. McFadden, Norah K. Judge, Hannah E. Navarrete, Britton C Michmerhuizen, Dominik Awad, Tracey L. Schultz, Paul W. Harms, Li Zhang, Teresa R. O’Meara, Jonathan Z. Sexton, Costas A. Lyssiotis, J. Michelle Kahlenberg, Mary X. O’Riordan
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114607- (2024)
Summary: Macrophage metabolic plasticity is central to inflammatory programming, yet mechanisms of coordinating metabolic and inflammatory programs during infection are poorly defined. Here, we show that type I interferon (IFN) temporally guides meta
Externí odkaz:
https://doaj.org/article/b80ebd8315f645efa79adec43f6f9598
Autor:
Bevin C. English, Hannah P. Savage, Scott P. Mahan, Vladimir E. Diaz-Ochoa, Briana M. Young, Basel H. Abuaita, Gautam Sule, Jason S. Knight, Mary X. O’Riordan, Andreas J. Bäumler, Renée M. Tsolis
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Immune cells must be able to adjust their metabolic programs to effectively carry out their effector functions. Here, we show that the endoplasmic reticulum (ER) stress sensor Inositol-requiring enzyme 1 alpha (IRE1α) and its downstream tra
Externí odkaz:
https://doaj.org/article/b52ea6eb6b7147e58bfa67beaabdb258
Autor:
Mack B. Reynolds, Hanna S. Hong, Britton C Michmerhuizen, Anna-Lisa E. Lawrence, Li Zhang, Jason S. Knight, Costas A. Lyssiotis, Basel H. Abuaita, Mary X. O’Riordan
Publikováno v:
Science Advances. 9
Macrophage metabolic plasticity enables repurposing of electron transport from energy generation to inflammation and host defense. Altered respiratory complex II function has been implicated in cancer, diabetes, and inflammation, but regulatory mecha
Autor:
Anna-Lisa E. Lawrence, Ryan P. Berger, David R. Hill, Sha Huang, Veda K. Yadagiri, Brooke Bons, Courtney Fields, Jason S. Knight, Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Basel H. Abuaita, Mary X. O’Riordan
Nontyphoidal strains of Salmonella enterica are a major cause of foodborne illnesses and infection with these bacteria result in inflammatory gastroenteritis. Neutrophils are a dominant immune cell type found at the site of infection in Salmonella-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b90399de98d57be29c6252cede601dd9
https://doi.org/10.1101/2022.08.09.503428
https://doi.org/10.1101/2022.08.09.503428
Autor:
Anna-Lisa E. Lawrence, Ryan P. Berger, David R. Hill, Sha Huang, Veda K. Yadagiri, Brooke Bons, Courtney Fields, Gautam J. Sule, Jason S. Knight, Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Mary X. O’Riordan, Basel H. Abuaita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56322d8204e4655785d47d6c762821c3
https://doi.org/10.15252/rc.2022454164
https://doi.org/10.15252/rc.2022454164
Autor:
Mack B. Reynolds, Hanna S. Hong, Britton C Michmerhuizen, Anna-Lisa E. Lawrence, Li Zhang, Jason S. Knight, Costas A. Lyssiotis, Basel H. Abuaita, Mary X. O’Riordan
Macrophage metabolic plasticity enables repurposing of electron transport from energy generation to inflammation and host defense. Altered Respiratory Complex II function has been implicated in cancer, diabetes and inflammation but regulatory mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d2a397689f695800312d18960585c6
https://doi.org/10.1101/2022.07.27.501734
https://doi.org/10.1101/2022.07.27.501734
Autor:
Anna-Lisa E. Lawrence, Ryan P. Berger, David R. Hill, Sha Huang, Veda K. Yadagiri, Brooke Bons, Courtney Fields, Gautam J. Sule, Jason S. Knight, Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Mary X. O’Riordan, Basel H. Abuaita
Infection of the human gut by Salmonella enterica Typhimurium (STM) results in a localized inflammatory disease that is not mimicked in murine infections. To determine mechanisms by which neutrophils, as early responders to bacterial challenge, direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c9ffc25b79d466c64fe229693570e3e
https://doi.org/10.1101/2022.03.25.485742
https://doi.org/10.1101/2022.03.25.485742
Autor:
Sonya J. Wolf, Christopher O. Audu, Amrita Joshi, Aaron denDekker, William J. Melvin, Frank M. Davis, Xianying Xing, Rachael Wasikowski, Lam C. Tsoi, Steven L. Kunkel, Johann E. Gudjonsson, Mary X. O’Riordan, J. Michelle Kahlenberg, Katherine A. Gallagher
Publikováno v:
JCI insight. 7(9)
Wound repair following acute injury requires a coordinated inflammatory response. Type I IFN signaling is important for regulating the inflammatory response after skin injury. IFN-κ, a type I IFN, has recently been found to drive skin inflammation i