Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Mary V. Gamble"'
Autor:
Irene Martinez-Morata, Faruque Parvez, Haotian Wu, Mahbubul Eunus, Jeff Goldsmith, Vesna Ilievski, Vesna Slavkovich, Olgica Balac, Chiugo Izuchukwu, Ronald A. Glabonjat, Tyler Ellis, Mohammad Nasir Uddin, Tariqul Islam, Anwar Sadat Arif, Alexander van Geen, Ana Navas-Acien, Joseph H. Graziano, Mary V. Gamble
Publikováno v:
Environment International, Vol 187, Iss , Pp 108715- (2024)
Background: Inorganic arsenic is metabolized to monomethyl- (MMAs) and dimethyl- (DMAs) species via one-carbon metabolism (OCM); this facilitates urinary arsenic elimination. OCM is influenced by folate and vitamin B12 and previous randomized control
Externí odkaz:
https://doaj.org/article/ddee0e40f6ca4d6ea473fd9b514b8cc9
Autor:
Jeliyah Clark, Paige Bommarito, Miroslav Stýblo, Marisela Rubio-Andrade, Gonzalo G. García-Vargas, Mary V. Gamble, Rebecca C. Fry
Publikováno v:
Environmental Health, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Background Inorganic arsenic (iAs) is a ubiquitous metalloid and drinking water contaminant. Prenatal exposure is associated with birth outcomes across multiple studies. During metabolism, iAs is sequentially methylated to mono- and di-methy
Externí odkaz:
https://doaj.org/article/d870f158e4d840448c3fed14c43c985d
Autor:
Anne K. Bozack, Philippe Boileau, Linqing Wei, Alan E. Hubbard, Fenna C. M. Sillé, Catterina Ferreccio, Johanna Acevedo, Lifang Hou, Vesna Ilievski, Craig M. Steinmaus, Martyn T. Smith, Ana Navas-Acien, Mary V. Gamble, Andres Cardenas
Publikováno v:
Environmental Health, Vol 20, Iss 1, Pp 1-18 (2021)
Abstract Background Arsenic (As) exposure through drinking water is a global public health concern. Epigenetic dysregulation including changes in DNA methylation (DNAm), may be involved in arsenic toxicity. Epigenome-wide association studies (EWAS) o
Externí odkaz:
https://doaj.org/article/fbd5d178b5c74f218f9bd30850656f17
Autor:
Ahlam Abuawad, Jeff Goldsmith, Julie B. Herbstman, Faruque Parvez, Tariqul Islam, Nancy LoIacono, Joseph H. Graziano, Ana Navas-Acien, Mary V. Gamble
Publikováno v:
Water, Vol 14, Iss 9, p 1477 (2022)
Urinary As (uAs) is a biomarker of As exposure. Urinary creatinine (uCr) or specific gravity (SG) are used to correct uAs for urine dilution. However, uCr is correlated with As methylation, whereas SG has limitations in individuals with kidney damage
Externí odkaz:
https://doaj.org/article/b84733d683934e6cb05d8ad37705a607
Autor:
Miranda J. Spratlen, Maria Grau-Perez, Jason G. Umans, Joseph Yracheta, Lyle G. Best, Kevin Francesconi, Walter Goessler, Poojitha Balakrishnan, Shelley A. Cole, Mary V. Gamble, Barbara V. Howard, Ana Navas-Acien
Publikováno v:
Environment International, Vol 121, Iss , Pp 728-740 (2018)
Background: Inorganic arsenic exposure and inter-individual differences in its metabolism have been associated with cardiometabolic risk. A more efficient arsenic metabolism profile (lower MMA%, higher DMA%) has been associated with reduced risk for
Externí odkaz:
https://doaj.org/article/74e12a40bd9043ca9d829b636671d1a0
Autor:
Ahlam Abuawad, Miranda J. Spratlen, Faruque Parvez, Vesna Slavkovich, Vesna Ilievski, Angela M. Lomax-Luu, Roheeni Saxena, Hasan Shahriar, Mohammad Nasir Uddin, Tariqul Islam, Joseph H. Graziano, Ana Navas-Acien, Mary V. Gamble
Publikováno v:
Environment International, Vol 149, Iss , Pp 106401- (2021)
Background: Water-borne arsenic (As) exposure is a global health problem. Once ingested, inorganic As (iAs) is methylated to mono-methyl (MMA) and dimethyl (DMA) arsenicals via one-carbon metabolism (OCM). People with higher relative percentage of MM
Externí odkaz:
https://doaj.org/article/63a245c1ad4b4335b88f2e947ef6c928
Autor:
Marisa H. Sobel, Tiffany R. Sanchez, Miranda R. Jones, Joel D. Kaufman, Kevin A. Francesconi, Michael J. Blaha, Dhananjay Vaidya, Daichi Shimbo, Walter Gossler, Mary V. Gamble, Jeanine M. Genkinger, Ana Navas‐Acien
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)
Background Arsenic‐related cardiovascular effects at exposure levels below the US Environmental Protection Agency's standard of 10 μg/L are unclear. For these populations, food, especially rice, is a major source of exposure. We investigated assoc
Externí odkaz:
https://doaj.org/article/fa480ff1ea5545fb90ccdec3372abddd
Autor:
Mary V. Gamble, Enyuan Shang, Roseann Piantedosi Zott, James R. Mertz, Debra J. Wolgemuth, William S. Blaner
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 12, Pp 2279-2292 (1999)
We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed that this enzyme plays an important role in synthesis of the transcriptionally active retinoid, 9-cis-retinoic acid. There
Externí odkaz:
https://doaj.org/article/e432aeefdcd34c029cba0351ffea3e3c
Autor:
Megan N. Hall, Mary V. Gamble
Publikováno v:
Journal of Toxicology, Vol 2012 (2012)
Exposure to arsenic (As) through drinking water is a substantial problem worldwide. The methylation of As, a reactive metalloid, generates monomethyl- (MMA) and dimethyl-arsenical (DMA) species. The biochemical pathway that catalyzes these reactions,
Externí odkaz:
https://doaj.org/article/e7510a1972e84ebfa9fcb0bc8a8e56c1
Background: DNA methylation microarrays have become an increasingly popular means of studying the role of epigenetics in cancer, although the methods used to analyze these arrays are still being developed and existing methods are not always widely di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108f76c70eb6e1ff3104693918f4510f
https://doi.org/10.1158/1055-9965.c.6515455
https://doi.org/10.1158/1055-9965.c.6515455