Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Mary Taub"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
2-Hydroxyglutarate (2HG) overproducing tumors arise in a number of tissues, including the kidney. The tumorigenesis resulting from overproduced 2HG has been attributed to the ability of 2HG alter gene expression by inhibiting α-ketoglutarate (αKG)-
Externí odkaz:
https://doaj.org/article/8d1aef0720614c62a226994c1a467a98
Autor:
Mary Taub, Facundo Cutuli
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 419-422 (2016)
This data article is concerned with chronic regulation of Na,K-ATPase by catecholamines. After a chronic treatment, inhibition of Na,K-ATPase activity was observed in cultures with dopamine, while a stimulation was observed in cultures treated with n
Externí odkaz:
https://doaj.org/article/5b9c6f5f4c3f422e9495eb33fdef5f35
Publikováno v:
BioTechniques, Vol 25, Iss 6, Pp 990-996 (1998)
The use of colloidal silica as a substratum for primary cultures of differentiated cells has significant advantages over classic tissue culture polystyrene. In this report, the growth and the level of expression of differentiated function of primary
Externí odkaz:
https://doaj.org/article/a041725b45074f29823dd462742dc2e8
Autor:
Mary Taub
L-2-Hydroxyglutarate (L2HG) overproducing Renal Cell Carcinomas (RCCs) arise in the kidney due to the genetic loss of L-2HG Dehydrogenase (L2HGDH), the enzyme responsible for the metabolism of L2HG. The overproduced 2-Hydroxyglutarate (2HG) promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29629b9f3542fd0dde5ea521a35dce82
https://mts.intechopen.com/articles/show/title/oncometabolite-l-2-hydroxyglutarate-promotes-oncogenesis-of-renal-cell-carcinomas-by-down-regulating
https://mts.intechopen.com/articles/show/title/oncometabolite-l-2-hydroxyglutarate-promotes-oncogenesis-of-renal-cell-carcinomas-by-down-regulating
Autor:
Mary Taub
Publikováno v:
Biochemical and Biophysical Research Communications. 471:342-347
Troglitazone has been used to suppress the growth of a number of tumors through apoptosis and autophagy. However, previous in vitro studies have employed very high concentrations of troglitazone (≥10(-5) M) in order to elicit growth inhibitory effe
Autor:
Mary Taub
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2086 (2018)
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2086 (2018)
For many years, studies concerning the regulation of Na,K-ATPase were restricted to acute regulatory mechanisms, which affected the phosphorylation of Na,K-ATPase, and thus its retention on the plasma membrane. However, in recent years, this focus ha
Autor:
Mary Taub
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3219 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3219 (2019)
A number of signal transduction pathways are activated during Acute Kidney Injury (AKI). Of particular interest is the Salt Inducible Kinase (SIK) signaling network, and its effects on the Renal Proximal Tubule (RPT), one of the primary targets of in
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 120
Scorpion envenomation injures a number of organs, including the kidney. Mechanisms proposed to explain the renal tubule injury include direct effects of venom on tubule epithelial cells, as well as indirect effects of the autonomic nervous system, an
Autor:
Facundo Cutuli, Mary Taub
Publikováno v:
Biochemical and Biophysical Research Communications. 426:516-521
In cystinosis, renal proximal tubule (RPT) function is compromised, due to mutations in ctns, which encodes for the transporter cystinosin, which removes cystine from lysosomes. Altered RPT function in cystinosis has been attributed to decreased ATP,
Publikováno v:
Biochemical and Biophysical Research Communications. 407:355-359
Nephropathic cystinosis is an autosomal recessive disorder caused by mutations in the CTNS gene [1] , which encodes for a transporter (cystinosin) responsible for cystine efflux from lysosomes. In cystinotic renal proximal tubules (RPTs), the defect