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Autor:
Morris A. Leaffer, C. Rolland Chen, Mary Tan Fon, Thomas H. Smith, William W. Lee, Alan N. Fujiwara, David W. Henry
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 14:111-117
Reaction of adriamycinone with excess 14CH3Mgl and periodate cleavage of the resulting glycol (5) affords daunomycinone-14-14C (6). Bromination and hydrolysis of 6 gives adriamycinone-14-14C (8). Coupling of 6 and the 14-0-p-anisyldiphenyl-methyl der