Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mary T. Litzinger"'
Autor:
Bruce Huang, Mary T. Litzinger, James W. Hodge, Duane H. Hamilton, Alessandra Jales, Claudia Palena, Romaine I. Fernando, Andressa Ardiani, David Apelian, Jeffrey Schlom
Publikováno v:
Oncotarget
// Duane H. Hamilton 1,* , Mary T. Litzinger 1,* , Alessandra Jales 1 , Bruce Huang 1 , Romaine I. Fernando 1 , James W. Hodge 1 , Andressa Ardiani 1 , David Apelian 2 , Jeffrey Schlom 1,* , and Claudia Palena 1,* 1 Laboratory of Tumor Immunology and
Publikováno v:
Seminars in Oncology. 39:358-366
The epithelial-mesenchymal transition (EMT) is thought to be a critical step along the metastasis of carcinomas. In addition to gaining motility and invasiveness, tumor cells that undergo EMT also acquire increased resistance to many traditional canc
Autor:
Romaine I. Fernando, Claudia Palena, Mary T. Litzinger, Duane H. Hamilton, Marianne D. Castillo
Publikováno v:
Cancer Research. 71:5296-5306
The switch of tumor cells from an epithelial to a mesenchymal-like phenotype [designated as epithelial-to-mesenchymal transition (EMT)] is known to induce tumor cell motility and invasiveness, therefore promoting metastasis of solid carcinomas. Altho
Autor:
Duane H. Hamilton, Romaine I. Fernando, Bruce Huang, Claudia Palena, Mary T. Litzinger, Jeffrey Schlom
Publikováno v:
Experimental Biology and Medicine. 236:537-545
The switch of carcinoma cells from an epithelial to a mesenchymal-like phenotype, via a process designated ‘epithelial-to-mesenchymal transition (EMT),’ has been recognized as a relevant step in the metastasis of solid tumors. Additionally, this
Publikováno v:
The Journal of Immunology. 175:780-787
LPS-activated B cells, transduced with IgG fusion proteins, are highly tolerogenic APCs. To analyze the mechanisms for this B cell-delivered gene therapy, we first followed the fate of CFSE-labeled B cell blasts. These cells primarily localized to th
Autor:
Qing Cheng, Kwong Y. Tsang, Jeffrey Schlom, Patrizia Ferroni, Bruce Huang, Antonella Spila, Romaine I. Fernando, H. Kim Lyerly, Francesco Cavaliere, Fiorella Guadagni, Claudia Palena, Mario Roselli, Leopoldo Costarelli, Mary T. Litzinger, Caroline Jochems, Duane H. Hamilton
Publikováno v:
Scopus-Elsevier
The epithelial–mesenchymal transition (EMT) is a normal developmental process that allows the conversion of epithelial, polarized, and stationary cells into highly motile and invasive mesenchymal cells, a phenomenon required for the normal formatio
Autor:
Duane H. Hamilton, Antonella Spila, Joanne Tucker, Jeffrey Schlom, Bruce Huang, Leopoldo Costarelli, Jhessica Alessandroni, Raffaele Palmirotta, Mary T. Litzinger, Fiorella Guadagni, Romaine I. Fernando, Mario Roselli, Claudia Palena, Kwong Y. Tsang
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 18(14)
Purpose: The epithelial–mesenchymal transition (EMT) is emerging as a critical factor for the progression and metastasis of carcinomas, as well as drug resistance. The T-box transcription factor Brachyury has been recently characterized as a driver
Publikováno v:
Leukemia research. 34(10)
Adenoviral transduction with CD40L and poxviral transduction with B7-1, ICAM-1, and LFA-3 (TRICOM) have been used to enhance the antigen-presenting capacity of chronic lymphocytic leukemia (CLL) cells. This study compares the same vector (modified va
Autor:
Duane H. Hamilton, Claudia Palena, Mary T. Litzinger, Jeffrey Schlom, Romaine I. Fernando, Paola Trono
Publikováno v:
The Journal of clinical investigation. 120(2)
Metastatic disease is responsible for the majority of human cancer deaths. Understanding the molecular mechanisms of metastasis is a major step in designing effective cancer therapeutics. Here we show that the T-box transcription factor Brachyury ind
Autor:
Helen Sabzevari, Claudia Palena, Kwong-Yok Tsang, Kenneth A. Foon, Jeffrey Schlom, Mary T. Litzinger
Publikováno v:
Cancer immunology, immunotherapy : CII. 58(6)
In chronic lymphocytic leukemia (CLL), malignant B cells and nonmalignant T cells exhibit dysfunction. We previously demonstrated that infection of CLL cells with modified vaccinia Ankara (MVA) expressing the costimulatory molecules B7-1, ICAM-1, and