Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mary S. Lopez"'
Autor:
Carly Maves, Kahlilia C Morris-Blanco, Mary S. Lopez, Nancy Ly, Raghu Vemuganti, Robert J. Dempsey
Publikováno v:
Translational Stroke Research. 13:483-493
Due to their role in controlling translation, microRNAs emerged as novel therapeutic targets to modulate post-stroke outcomes. We previously reported that miR-21 is the most abundantly induced microRNA in the brain of rodents subjected to preconditio
Autor:
Mary S, Lopez, Kahlilia C, Morris-Blanco, Nancy, Ly, Carly, Maves, Robert J, Dempsey, Raghu, Vemuganti
Publikováno v:
Translational stroke research. 13(3)
Due to their role in controlling translation, microRNAs emerged as novel therapeutic targets to modulate post-stroke outcomes. We previously reported that miR-21 is the most abundantly induced microRNA in the brain of rodents subjected to preconditio
Autor:
Juan Paraíso-Luna, Mauricio Olguín-Albuerne, Mary S. Lopez, Robin J. Vigouroux, Mauricio M. Oliveira, Andressa Radiske, Ashfaqul Hoque, Sara Grassi, Sonja Meier, Mayara C. Ribeiro, Giulia Lunghi, Danielle Beckman, Maria Clara Selles, Sergi Roig‐Puiggros, Gimena Gomez, Nadia I. Bocai, Roberta Schellino, Paschalis Theotokis, Alain Chédotal, Joshua G. Davimes, S. Singh, Jonu Pradhan, Ana B. Ramos-Hryb, Thomas K. Karikari, Frederico C Kiffer, Pedzisai Mazengenya, Brian Chiou
Publikováno v:
Journal of Neurochemistry. 153:10-32
Perception of our environment entirely depends on the close interaction between the central and peripheral nervous system. In order to communicate each other, both systems must develop in parallel and in coordination. During development, axonal proje
Autor:
Viktoriya Bondarenko, Henry Resnikoff, Heather A. Simmons, Marina E. Emborg, Mary S. Lopez, Jeanette M. Metzger, Andres Mejia
Publikováno v:
Journal of Inflammation Research. 12:113-126
Background: Parkinson's disease (PD) patients frequently present gastrointestinal (GI) dysfunction that, in many cases, predates the onset of motor symptoms. In PD, the presynaptic protein alpha-synuclein (α-syn) undergoes pathological changes, incl
Autor:
Raghu Vemuganti, Jenna Kropp Schmidt, Mary S. Lopez, Megan E. Murphy, Jeanette M. Metzger, Marina E. Emborg
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Degeneration of sympathetic innervation of the heart occurs in numerous diseases, including diabetes, idiopathic REM sleep disorder, and Parkinson’s disease (PD). In PD, cardiac sympathetic denervation occurs in 80-90% of patients and can begin bef
Autor:
TaeHee Kim, Kahlilia C Morris-Blanco, Mary S. Lopez, Raghu Vemuganti, Bharath Chelluboina, Mario J. Bertogliat
Publikováno v:
Stroke
Background and Purpose— Epigenetics play a significant role in brain pathologies. We currently evaluated the role of a recently discovered brain-enriched epigenetic modification known as 5-hydroxymethylcytosine (5hmC) in regulating transcriptomic a
Publikováno v:
Mol Biol Rep
BACKGROUND: MicroRNAs (miRNAs) are emerging as novel molecular tools for diagnosing and treating diseases. Rhesus monkeys (Macaca mulatta) are the most widely used nonhuman primate species for biomedical studies, yet only 912 mature miRNAs have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f0a9eb621800a004c2789ad1e8afa4
https://europepmc.org/articles/PMC6778012/
https://europepmc.org/articles/PMC6778012/
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 36:1644-1650
The health benefits of the plant-derived polyphenol resveratrol were established in multiple disease systems. Notably, pre-treatment with resveratrol was shown to be neuroprotective in several models of cerebral ischemia. Mechanisms of resveratrol-me
Autor:
Mary S. Lopez, Raghu Vemuganti
Publikováno v:
Methods in Molecular Biology ISBN: 9781493975242
The middle cerebral artery occlusion (MCAO) model is widely used for inducing a focal cerebral ischemic insult (stroke) in rodents. Here, we describe a method for transient MCAO technique without craniotomy in both mice and rats. In our laboratory, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fad97955600970030320293c7af16931
https://doi.org/10.1007/978-1-4939-7526-6_9
https://doi.org/10.1007/978-1-4939-7526-6_9
Publikováno v:
Neurochemistry International. 89:75-82
Resveratrol, a stilbene formed in many plants in response to various stressors, elicits multiple beneficial effects in vertebrates. Particularly, resveratrol was shown to have therapeutic properties in cancer, atherosclerosis and neurodegeneration. R