Structural Evolution of Primate Glutamate Dehydrogenase 2 as Revealed by In Silico Predictions and Experimentally Determined Structures

Autor: Ionela Litso, Andreas Plaitakis, Vasiliki E. Fadouloglou, Mary Providaki, Michael Kokkinidis, Ioannis Zaganas

Publikováno v: Biomolecules, Vol 14, Iss 1, p 22 (2023)

Glutamate dehydrogenase (GDH) interconverts glutamate to a-ketoglutarate and ammonia, interconnecting amino acid and carbohydrate metabolism. In humans, two functional GDH genes, GLUD1 and GLUD2, encode for hGDH1 and hGDH2, respectively. GLUD2 evolve

Externí odkaz: https://doaj.org/article/527a46d2d2794c3a9a0c02dd7f94986e

Probing Protein Folding with Sequence-Reversed α-Helical Bundles

Autor: Charalambos Pozidis, Efstratios Mylonas, Melina Fotiadou, Maria Amprazi, Michael Kokkinidis, Aikaterini Kefala, Mary Providaki, Dina Kotsifaki

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 1955, p 1955 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International journal of molecular sciences 22(4), 1955 (1-21) (2021). doi:10.3390/ijms22041955

International journal of molecular sciences 22(4), 1955 (1-21) (2021). doi:10.3390/ijms22041955
Recurrent protein folding motifs include various types of helical bundles formed by α-helices that supercoil around each other. While specific patte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acbff5ebfc4f80dc233aa0ce98660e5
https://doi.org/10.3390/ijms22041955

Structure and expression of LeMA-1, a tomato protein belonging to the SEC18-PAS1-CDC48-TBP-1 protein family of putative Mg2+-dependent ATPases

Autor: Mina Tsagris, Anastasia Prombona, Mary Providaki, Martin Tabler

Publikováno v: Plant Molecular Biology. 27:1109-1118

cDNA clones of a tomato protein, called Lycopersicum esculentum putative Mg(2+)-dependent ATPase (LeMA-1), were isolated from a cDNA library. Sequence comparison of the tomato protein with other genes in the database revealed that the protein is high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07db8029af59942af023a5efbbc2302b
https://doi.org/10.1007/bf00020884

Purification, crystallization and preliminary X-ray diffraction analysis of a variant of the ColE1 Rop protein

Autor: Mary Providaki, Michael Kokkinidis, Evangelia G. Kapetaniou, Maria Ambrazi, George Fellas, Dina Kotsifaki

Publikováno v: Acta crystallographica / F 64, 434 (2008). doi:10.1107/S1744309108011342

Rop is the paradigm of a canonical four-alpha-helical bundle. Its loop region has attracted considerable interest because a single alanine-to-proline substitution (A31P) in the loop is sufficient to change the topology of this small protein. In order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ef205b4d21057de479c5622c2b3358
https://europepmc.org/articles/PMC2376389/

Collagen-gel-induced resistance of overlying keratinocyte cultures to photosensitization

Autor: Savas Georgiou, Andronicki D. Tosca, John C. Katsantonis, Mary Providaki, John G. Vlahonikolis

Publikováno v: Photochemotherapy: Photodynamic Therapy and Other Modalities III.

In the present study it was found that human keratinocytes grown on collagen substrate, exhibited increased resistance to the hematoprophyrin-mediated photodynamic treatment, in comparison to keratinocytes grown on Petri dishes without collagen. Inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cf5b21e8a2b2b50f841839dfd23fe43
https://doi.org/10.1117/12.297792