Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mary Popov"'
Autor:
Taejin Kim, Mathias Viard, Kirill A. Afonin, Kshitij Gupta, Mary Popov, Jacqueline Salotti, Peter F. Johnson, Charles Linder, Eliahu Heldman, Bruce A. Shapiro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 359-372 (2020)
Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However,
Externí odkaz:
https://doaj.org/article/bb90cca83bf74e98a8a3fce08ace1da7
Autor:
Jawdat Al-Bassam, Sudhir Kumar Singh, Mary Popov, Larisa Gheber, Sayaka Inagaki, Himanshu Pandey, Steven S. Rosenfeld, Mayan Sadan, Raz Zarivach, Geula Davidov, Meenakshi Singh
Publikováno v:
Cellular and Molecular Life Sciences. 78:6051-6068
Two modes of motility have been reported for bi-directional kinesin-5 motors: (a) context-dependent directionality reversal, a mode in which motors undergo persistent minus-end directed motility at the single-molecule level and switch to plus-end dir
Autor:
Jacqueline Salotti, Kirill A. Afonin, Mary Popov, Eliahu Heldman, Mathias Viard, Charles Linder, Taejin Kim, Peter F. Johnson, Kshitij Gupta, Bruce A. Shapiro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss, Pp 359-372 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However,
Autor:
Stanislav Popov, Semion Entus, Marina Shenker, Yoram Shotland, Oshra Saphier, Mary Popov, Magal Saphier
Publikováno v:
Current Microbiology. 77:361-368
This study continues the series of experiments that demonstrate the high antibacterial properties of monovalent copper ions (Cu+). While in previous study we examined different metals (copper and silver) and their metal states (mono- and divalent), s
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6420, p 6420 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6420, p 6420 (2021)
Bipolar kinesin-5 motor proteins perform multiple intracellular functions, mainly during mitotic cell division. Their specialized structural characteristics enable these motors to perform their essential functions by crosslinking and sliding apart an
Autor:
Yaron Berger, Eyal Nir, Dinesh Chandra Khara, Miran Liber, Jürgen Jopp, Mary Popov, Breveruos Sheheade
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 15(51)
Efficient fabrication of structurally and functionally diverse nanomolecular devices and machines by organizing separately prepared DNA origami building blocks into a larger structure is limited by origami attachment yields. A general method that ena
Autor:
Miran Liber, Eyal Nir, Mary Popov, Roman Tsukanov, Yaron Berger, Toma E. Tomov, Dinesh Chandra Khara
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 14(23)
Organizing DNA origami building blocks into higher order structures is essential for fabrication of large structurally and functionally diverse devices and molecular machines. Unfortunately, the yields of origami building block attachment reactions a
Autor:
Charles Linder, Ibrahim Abu Hammad, Sarina Grinberg, David Stepensky, Eliahu Heldman, Tzach Bachar, Mary Popov
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 85:381-389
Inefficient drug delivery to the brain is a major obstacle for pharmacological management of brain diseases. We investigated the ability of bolavesicles - monolayer membrane vesicles self-assembled from synthetic bolaamphiphiles that contain two hydr
Autor:
Charles Linder, Sarina Grinberg, Mary Popov, Tal Waner, Bosmat Levi-Hevroni, Richard J. Deckelbaum, Eliahu Heldman
Publikováno v:
Journal of Controlled Release. 160:306-314
Stable nano-sized vesicles with a monolayer encapsulating membrane were prepared from novel bolaamphiphiles with choline ester head groups. The head groups were covalently bound to the alkyl chain of the bolaamphiphiles either via the nitrogen atom o
Publikováno v:
ACS Chemical Neuroscience. 1:399-406
Many peptides with the potential of therapeutic action for brain disorders are not in clinical use because they are unable to cross the blood-brain barrier (BBB) following peripheral administration. We have developed two potential strategies for the