Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mary Pahuski"'
Autor:
Aurora Esquela-Kerscher, Richard Drake, Vitold Galkin, Lifang Yang, O. John Semmes, Aleena Short, Mary Pahuski, Garrison J. Glavich, Tsuyoshi Hasegawa
This supplemental data file consists of 3 supplemental tables and 8 supplemental figures. Suppl. Tables 1-2 lists specific miRNA mimics, inhibitors, TaqMan and PCR primers used in the in vitro functional assays depicted in Figs. 1-4, 6-7. Suppl. Tabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ede356161255e9c0785f9f4a9e22b7
https://doi.org/10.1158/1541-7786.22515397.v1
https://doi.org/10.1158/1541-7786.22515397.v1
Data from Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate
Autor:
Aurora Esquela-Kerscher, Richard Drake, Vitold Galkin, Lifang Yang, O. John Semmes, Aleena Short, Mary Pahuski, Garrison J. Glavich, Tsuyoshi Hasegawa
Prostate cancer afflicts 1 in 7 men and is the second leading cause of male cancer-related deaths in the United States. MicroRNAs (miRNAs), an extensive class of approximately 22 nucleotide noncoding RNAs, are often aberrantly expressed in tissues an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d115ceecbc31d85efe54d7a33c93aafc
https://doi.org/10.1158/1541-7786.c.6541072
https://doi.org/10.1158/1541-7786.c.6541072
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Supplementary methods containing descriptions of PCR primer sequences, Reverse Phase Protein Arrays, RNA-seq, and Rescue Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04dd685fe00c0cdfbe7215d5b464da
https://doi.org/10.1158/0008-5472.22413443.v1
https://doi.org/10.1158/0008-5472.22413443.v1
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Supplementary figures: 1): molecular structure of mibefradil, 2) Mibefradil effects on HIFs, 3) effects of sh-RNA inhibition of Cav3.2 in GSCs, 4) Schematic summary of the findings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abf13a9118e0ab59d5144def36f51f2
https://doi.org/10.1158/0008-5472.22413440
https://doi.org/10.1158/0008-5472.22413440
Autor:
Roger Abounader, Emanuel Petricoin, See Phan, David Schiff, Julia Wulfkuhle, Isela Gallagher, Karim Saoud, Ciana Deveau, Baomin Wang, Fadila Guessous, Collin Dube, Mary Pahuski, Cassandra Grello, Madison Oxford, Fang Yuan, Myron Gibert, Sarah Hine, Ying Zhang, Nichola Cruickshanks
Purpose:Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or overactivated in GBM. Although clinically applicable MET inhibitors have been developed, resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e87c3eb9e23819597034c082110d07f
https://doi.org/10.1158/1078-0432.c.6529293.v1
https://doi.org/10.1158/1078-0432.c.6529293.v1
Autor:
Roger Abounader, Emanuel Petricoin, See Phan, David Schiff, Julia Wulfkuhle, Isela Gallagher, Karim Saoud, Ciana Deveau, Baomin Wang, Fadila Guessous, Collin Dube, Mary Pahuski, Cassandra Grello, Madison Oxford, Fang Yuan, Myron Gibert, Sarah Hine, Ying Zhang, Nichola Cruickshanks
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40125f8bc84279a9e294f1e45f9e4b63
https://doi.org/10.1158/1078-0432.22476102
https://doi.org/10.1158/1078-0432.22476102
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how GSCs can be targeted by the FDA-approved drug mibefradil, which inhibits the T-type calcium channel Cav3.2. This calcium cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cd1f54f8281700ec886b6615dbf2b4
https://doi.org/10.1158/0008-5472.c.6508712.v1
https://doi.org/10.1158/0008-5472.c.6508712.v1
Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma
Autor:
Mary Pahuski, David Schiff, Madison Oxford, Fadila Guessous, Karim Saoud, Collin Dube, Nichola Cruickshanks, Emanuel F. Petricoin, Isela Gallagher, Myron Gibert, Sarah Hine, Ying Zhang, Ciana Deveau, Fang Yuan, Julia Wulfkuhle, Cassandra Grello, S. Phan, Baomin Wang, Roger Abounader
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(2)
Purpose: Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or overactivated in GBM. Although clinically applicable MET inhibitors have been developed, resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60338439209c661d7757cee81231b33d
https://pubmed.ncbi.nlm.nih.gov/30201763
https://pubmed.ncbi.nlm.nih.gov/30201763
Autor:
Garrison Glavich, Aleena M. Short, Tsuyoshi Hasegawa, Lifang Yang, Richard R. Drake, Vitold E. Galkin, O. John Semmes, Aurora Esquela-Kerscher, Mary Pahuski
Prostate cancer afflicts 1 in 7 men and is the second leading cause of male cancer-related deaths in the United States. MicroRNAs (miRNAs), an extensive class of approximately 22 nucleotide noncoding RNAs, are often aberrantly expressed in tissues an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1157a03f7043944fb5dc377e855df0b9
https://europepmc.org/articles/PMC5882523/
https://europepmc.org/articles/PMC5882523/
Autor:
Roger Abounader, Ying Zhang, David Schiff, Nichola Cruickshanks, Anindya Dutta, Fang Yuan, Mary Pahuski, Benjamin Purow
Publikováno v:
Glioblastoma ISBN: 9780994438126
The vast majority of the human genome is transcribed into noncoding RNAs. Among these, microRNAs (miRNA) and long noncoding RNAs (lncRNA) are frequently deregulated in cancer, where they regulate a wide variety of functions. Glioblastoma (GBM) is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29312e87b579bab0405fd77ba35ec88
https://doi.org/10.15586/codon.glioblastoma.2017.ch6
https://doi.org/10.15586/codon.glioblastoma.2017.ch6