Nutritional basis for colonization resistance by human commensal Escherichia coli strains HS and Nissle 1917 against E. coli O157:H7 in the mouse intestine.

Autor: Rosalie Maltby, Mary P Leatham-Jensen, Terri Gibson, Paul S Cohen, Tyrrell Conway

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e53957 (2013)

Escherichia coli is a single species consisting of many biotypes, some of which are commensal colonizers of mammals and others that cause disease. Humans are colonized on average with five commensal biotypes, and it is widely thought that the commens

Externí odkaz: https://doaj.org/article/8533d76ead2f4885b1866ca3c7317a60

Distinct roles for canonical and variant histone H3 lysine 36 in Polycomb silencing

Autor: Harmony R. Salzler, Vasudha Vandadi, Benjamin D. McMichael, John C. Brown, Sally A. Boerma, Mary P. Leatham-Jensen, Kirsten M. Adams, Michael P. Meers, Jeremy M. Simon, Robert J. Duronio, Daniel J. McKay, A. Gregory Matera

Polycomb complexes regulate cell-type specific gene expression programs through heritable silencing of target genes. Trimethylation of histone H3 lysine 27 (H3K27me3) is essential for this process. Perturbation of H3K36 is thought to interfere with H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77bcd1af26ca49165e118fea4af7e9d6
https://doi.org/10.1101/2022.10.11.511749

An Escherichia coli Nissle 1917 Missense Mutant Colonizes the Streptomycin-Treated Mouse Intestine Better than the Wild Type but Is Not a Better Probiotic

Autor: Paul S. Cohen, Jimmy Adediran, Tyrrell Conway, Mary P. Leatham-Jensen, Matthew E. Mokszycki, Jakob Frimodt-Møller, Linda J. Kenney, Karen A. Krogfelt, Krystyna Kazmierczak

Publikováno v: Infection and Immunity. 82:670-682

Previously we reported that the streptomycin-treated mouse intestine selected for two different Escherichia coli MG1655 mutants with improved colonizing ability: nonmotile E. coli MG1655 flhDC deletion mutants that grew 15% faster in vitro in mouse c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4e5c00aa0263fac0f2e62ee00a1f5f
https://doi.org/10.1128/iai.01149-13

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

Autor: Karen A. Krogfelt, Robert W. Deering, Niels Frimodt-Møller, Veronika Tchesnokova, Mary P. Leatham-Jensen, Matthew E. Mokszycki, David C. Rowley, Evgeni V. Sokurenko, Jodi L. Camberg, Karen Leth Nielsen, Paul S. Cohen, Gongqin Sun, Jakob Frimodt-Møller

Publikováno v: mSphere
mSphere, Vol 1, Iss 1 (2016)
Leatham-Jensen, M P, Mokszycki, M E, Rowley, D C, Deering, R, Camberg, J L, Sokurenko, E V, Tchesnokova, V L, Frimodt-Møller, J, Krogfelt, K A, Nielsen, K L, Frimodt-Møller, N, Sun, G & Cohen, P S 2016, ' Uropathogenic Escherichia coli metabolite-dependent quiescence and persistence may explain antibiotic tolerance during urinary tract infection ', mSphere, vol. 1, no. 1, e00055-15 . https://doi.org/10.1128/mSphere.00055-15

Recurrent urinary tract infections (UTIs) affect 10 to 40% of women. In up to 77% of those cases, the recurrent infections are caused by the same uropathogenic E. coli (UPEC) strain that caused the initial infection. Upon infection of urothelial tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a84976903d6e97ccfc1ad8475ebd0d
https://pubmed.ncbi.nlm.nih.gov/27303698

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

Autor: Mary P. Leatham-Jensen, Matthew E. Mokszycki, David C. Rowley, Robert Deering, Jodi L. Camberg, Evgeni V. Sokurenko, Veronika L. Tchesnokova, Jakob Frimodt-Møller, Karen A. Krogfelt, Karen Leth Nielsen, Niels Frimodt-Møller, Gongqin Sun, Paul S. Cohen

Publikováno v: mSphere, Vol 1, Iss 1 (2016)

ABSTRACT In the present study, it is shown that although Escherichia coli CFT073, a human uropathogenic (UPEC) strain, grows in liquid glucose M9 minimal medium, it fails to grow on glucose M9 minimal medium agar plates seeded with ≤106 CFU. The ce

Externí odkaz: https://doaj.org/article/6497ab76beaa4d5e949dc9769acc0652