Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mary P LaPierre"'
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M. Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F. Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M. Kangas, Anniina E. Hiltunen, Emma Gribchenko, Minna U. Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T. Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P. LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B. Hansen, Tarja Malm
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113862- (2024)
Summary: Brain functionality relies on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7 (also known as CDR1as), the microRNA miR-7, and the long ncRNA Cyrano. We de
Externí odkaz:
https://doaj.org/article/3f5181ebf602423b89fa5aca16a2796d
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The hypothalamus controls systemic energy homeostasis. Here, the authors show that loss of microRNA-7 in hypothalamic neurons causes obesity, increased growth and endocrine dysfunction in mice, and report genetic evidence that links microRNA-7 to hei
Externí odkaz:
https://doaj.org/article/8bfa6026caf5401ea30667ba99f03f1a
Autor:
Ricards Marcinkevics, Pamuditha N. Silva, Anna-Katharina Hankele, Charlyn Dörnte, Sarah Kadelka, Katharina Csik, Svenja Godbersen, Algera Goga, Lynn Hasenöhrl, Pascale Hirschi, Hasan Kabakci, Mary P. LaPierre, Johanna Mayrhofer, Alexandra C. Title, Xuan Shu, Nouell Baiioud, Sandra Bernal, Laura Dassisti, Mara D. Saenz-de-Juano, Meret Schmidhauser, Giulia Silvestrelli, Simon Z. Ulbrich, Thea J. Ulbrich, Tamara Wyss, Daniel J. Stekhoven, Faisal S. Al-Quaddoomi, Shuqing Yu, Mascha Binder, Christoph Schultheiβ, Claudia Zindel, Christoph Kolling, Jörg Goldhahn, Bahram Kasmapour Seighalani, Polina Zjablovskaja, Frank Hardung, Marc Schuster, Anne Richter, Yi-Ju Huang, Gereon Lauer, Herrad Baurmann, Jun Siong Low, Daniela Vaqueirinho, Sandra Jovic, Luca Piccoli, Sandra Ciesek, Julia E. Vogt, Federica Sallusto, Markus Stoffel, Susanne E. Ulbrich
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces B and T cell responses, contributing to virus neutralization. In a cohort of 2,911 young adults, we identified 65 individuals who had an asymptomatic or mildly symptomatic SARS-
Externí odkaz:
https://doaj.org/article/5ed868f2a518448cb1a26993a166470f
Autor:
Mary P. LaPierre, Markus Stoffel
Publikováno v:
Molecular Metabolism, Vol 6, Iss 9, Pp 1010-1023 (2017)
Background: MicroRNAs have emerged as important regulatory non-coding RNAs that tune cellular responses to physiological perturbations and disease conditions. An increasing body of literature underlines the important roles of miRNA function in pancre
Externí odkaz:
https://doaj.org/article/9a04c0d0087b4992af3b5bcee778de15
Autor:
Beatrice M. Filippi, Mona A. Abraham, Pamuditha N. Silva, Mozhgan Rasti, Mary P. LaPierre, Paige V. Bauer, Jonathan V. Rocheleau, Tony K.T. Lam
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2301-2309 (2017)
Mitochondria undergo dynamic changes to maintain function in eukaryotic cells. Insulin action in parallel regulates glucose homeostasis, but whether specific changes in mitochondrial dynamics alter insulin action and glucose homeostasis remains elusi
Externí odkaz:
https://doaj.org/article/f01fa4994a2840558b2ffa59dc028edd
Autor:
Jessica T. Y. Yue, Mona A. Abraham, Paige V. Bauer, Mary P. LaPierre, Peili Wang, Frank A. Duca, Beatrice M. Filippi, Owen Chan, Tony K. T. Lam
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Glycine sensing in the dorsal vagal complex (DVC) regulates hepatic glucose production in rodents. Here the authors show that pharmacological and molecular inhibition of glycine reuptake in the DVC potentiates NMDA receptors, and improves metabolic h
Externí odkaz:
https://doaj.org/article/39518d1b32d94bf387969a5e946ba9b7
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M Kangas, Anniina E Hiltunen, Minna U Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B Hansen, Malm Tarja
Brain functionality resides on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7, the microRNA miR-7 and the long non-coding RNA Cyrano. However, very little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e1bb4b25620fb6dfa176ceecb3a6d4
https://doi.org/10.1101/2023.01.24.525136
https://doi.org/10.1101/2023.01.24.525136
Autor:
Mònica Torres Esteban, Anaïs Nura Schad, Mathias Treier, Svenja Godbersen, Mary P LaPierre, Markus Stoffel, Umesh Ghoshdastider
Publikováno v:
Endocrinology
Endocrinology, 162 (2)
Endocrinology, 162 (2)
Prolactin production is controlled by a complex and temporally dynamic network of factors. Despite this tightly coordinated system, pathological hyperprolactinemia is a common endocrine disorder that is often not understood, thereby highlighting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66141ec474648fb92a40ce26e01574d
https://doi.org/10.1210/endocr/bqaa220
https://doi.org/10.1210/endocr/bqaa220
Autor:
Markus Stoffel, Mary P. LaPierre
Publikováno v:
Molecular Metabolism, Vol 6, Iss 9, Pp 1010-1023 (2017)
Molecular Metabolism
Molecular Metabolism, 6 (9)
Molecular Metabolism
Molecular Metabolism, 6 (9)
Background MicroRNAs have emerged as important regulatory non-coding RNAs that tune cellular responses to physiological perturbations and disease conditions. An increasing body of literature underlines the important roles of miRNA function in pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5724e12da0a8d3deb4dd96eb93df3c18
Autor:
Mathieu Latreille, Markus Stoffel, Emanuel Gasser, Mary P. LaPierre, Yinjie Yang, Kashan Ahmed, Jukka Kero, Thomas Rülicke, Rémy Denzler
MicroRNAs (miRNAs) are negative modulators of gene expression that fine-tune numerous biological processes. miRNA loss-of-function rarely results in highly penetrant phenotypes, but rather, influences cellular responses to physiologic and pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166ef484bd5a2f3e65b1e0c004c4c3bd
http://hdl.handle.net/10044/1/44431
http://hdl.handle.net/10044/1/44431