Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mary O. Gray"'
Autor:
Mary O. Gray, Dipak K. Das, Edward J. Neafsey, Kenneth J. Mukamal, Dale A. Parks, Ronald J. Korthuis, Michael A. Collins
Publikováno v:
Alcoholism: Clinical and Experimental Research. 33:206-219
In contrast to many years of important research and clinical attention to the pathological effects of alcohol (ethanol) abuse, the past several decades have seen the publication of a number of peer-reviewed studies indicating the beneficial effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa29e8373bf4048de3f4903f1aea91d
https://doi.org/10.1111/j.1530-0277.2008.00828.x
https://doi.org/10.1111/j.1530-0277.2008.00828.x
Autor:
Joel S. Karliner, Norman Honbo, Mary O. Gray, Kanu Chatterjee, Edward J. Goetzl, Jianqing Zhang
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H3150-H3158
Sphingosine 1-phosphate (S1P) is a biologically active lysophospholipid that serves as a key regulator of cellular differentiation and survival. Immune stimuli increase S1P synthesis and secretion by mast cells and platelets, implicating this molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592b59b077aab6cd1a26cc87939dd0c1
https://doi.org/10.1152/ajpheart.00587.2006
https://doi.org/10.1152/ajpheart.00587.2006
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H714-H723
Poly(ADP-ribose) polymerase-1 (PARP-1), the most abundant member of the PARP family, is a nuclear enzyme that catalyzes ADP-ribose transfer from NAD+to specific acceptor proteins in response to DNA damage. Excessive PARP-1 activation is an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8600113e2da7f9596407408e76a6efd1
https://doi.org/10.1152/ajpheart.00823.2005
https://doi.org/10.1152/ajpheart.00823.2005
Autor:
Daria Mochly-Rosen, Mary O. Gray, Hui Zhong Zhou, Robert O. Messing, Peili Zhu, Ingeborg Schafhalter-Zoppoth
Publikováno v:
Journal of Biological Chemistry. 279:3596-3604
Signaling pathways involving protein kinase C isozymes are modulators of cardiovascular development and response to injury. Protein kinase C epsilon activation in cardiac myocytes reduces necrosis caused by coronary artery disease. However, it is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8771f01953808a4c4f6d429de6e30875
https://doi.org/10.1074/jbc.m311459200
https://doi.org/10.1074/jbc.m311459200
Autor:
Yelizaveta Sher, Elena Maklashina, Gary Cecchini, Hui-Zhong Zhou, Mary O. Gray, Joel S. Karliner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1556(1):6-12
The multi-subunit mammalian NADH–ubiquinone oxidoreductase (complex I) is part of the mitochondrial electron transport chain and physiologically serves to reduce ubiquinone with NADH as the electron donor. The three-dimensional structure of this en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75ed359adfa970b61589d7f07e7136f
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 283:H165-H174
C57BL/6 mice were fed 18% ethanol (vol/vol) in drinking water for 12 wk. Isovolumic hearts were subjected to 20 min of ischemia and 30 min of reperfusion on a Langendorff apparatus. There were no differences in baseline hemodynamic function between h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7e43772c6a402b49d83ee94045f823
https://doi.org/10.1152/ajpheart.00408.2001
https://doi.org/10.1152/ajpheart.00408.2001
Autor:
Zhu-Qiu Jin, Peili Zhu, Hui Zhong Zhou, Daria Mochly-Rosen, Edward J. Goetzl, Mary O. Gray, Norman Honbo, Robert O. Messing, Joel S. Karliner
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 282:H1970-H1977
Sphingosine-1-phosphate (S1P) protects neonatal rat cardiac myocytes from hypoxic damage through unknown signaling pathways. We tested the hypothesis that S1P-induced cardioprotection requires activation by the epsilon-isoform of protein kinase C (PK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79221311033756f47df26adc3b9f3efd
https://doi.org/10.1152/ajpheart.01029.2001
https://doi.org/10.1152/ajpheart.01029.2001
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:1713-1717
The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) stimulate cellular proliferation and affect numerous cellular functions by signaling through G protein-coupled endothelial differentiation gene-encoded (Edg) receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140e919be4c54fd548059707d498d83b
https://doi.org/10.1006/jmcc.2001.1429
https://doi.org/10.1006/jmcc.2001.1429
Autor:
Mary O. Gray, Norman Honbo, Marina R. Bergman, Lucia Piacentini, Jamila Chentoufi, Joel S. Karliner
Publikováno v:
Journal of Molecular and Cellular Cardiology. 32:565-576
After myocardial ischemia, circulating levels of the mitogen endothelin-1 (ET-1) increase. The effects of ET-1 on cardiac fibroblasts are poorly characterized. Therefore we examined the influence of ET-1 on cardiac fibroblast proliferation with a vie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e39d949f78ff4c0a29cac87f6bd479
https://doi.org/10.1006/jmcc.2000.1109
https://doi.org/10.1006/jmcc.2000.1109
Publikováno v:
Proceedings of the National Academy of Sciences. 96:12784-12789
Recent epidemiological studies indicate beneficial effects of moderate ethanol consumption in ischemic heart disease. Most studies, however, focus on the effect of long-term consumption of ethanol. In this study, we determined whether brief exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40946bdf433c956acb2f3b28ef78fa48
https://doi.org/10.1073/pnas.96.22.12784
https://doi.org/10.1073/pnas.96.22.12784