Zobrazeno 1 - 10
of 729
pro vyhledávání: '"Mary O'brien"'
Autor:
Solange Peters, Urania Dafni, Panagiota Zygoura, Sanjay Popat, Mary O'Brien, Rolf A Stahel, Alessandra Curioni-Fontecedro, Georges Coukos, Amy Roy, Riyaz Shah, Krisztian Homicsko, James Spicer, Stephen P Finn, David Gilligan, Maxim Norkin, Stephanie Tissot, Nicholas Shakarishvili, Anthony Pope, Patricia Fisher, Sylvie Rusakiewicz, Ekaterina Fortis, Nesa Marti, Roswitha Kammler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Few tissue biomarkers exist to date that could enrich patient with cancer populations to benefit from immune checkpoint blockade by programmed cell death protein 1/ligand-1 (PD-/L-1) inhibitors. PD-L1 expression has value in this context i
Externí odkaz:
https://doaj.org/article/6dd7fca327104b5ea4d8c47266ef755b
Autor:
Andrew Rodenhouse, M. A. Hassan Talukder, Jung Il Lee, Prem Kumar Govindappa, Mary O’Brien, Kristen M. Manto, Kelsey Lloyd, Grant D. Wandling, Justin R. Wright, Jeremy R. Chen See, Samantha L. Anderson, Regina Lamendella, John P. Hegarty, John C. Elfar
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Objective Antibiotics (ABX) are widely used for life-threatening infections and also for routine surgical operations. Compelling evidence suggests that ABX-induced alterations of gut microbiota composition, termed dysbiosis, are linked with
Externí odkaz:
https://doaj.org/article/3e32ea2f0bce4b5594f70bdabe5bec9c
Autor:
Tanvir C. Turin, Nashit Chowdhury, Mark Ekpekurede, Deidre Lake, Mohammad Ali Ashraf Lasker, Mary O’Brien, Suzanne Goopy
Publikováno v:
Human Resources for Health, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background There is a growing recognition that underutilization and underemployment of skilled immigrants, especially internationally trained health professionals, creates a financial burden on individuals and economic losses for the host co
Externí odkaz:
https://doaj.org/article/92634d27288c495895f4bbda47415c63
Autor:
Jung Il Lee, Anagha A. Gurjar, M. A. Hassan Talukder, Andrew Rodenhouse, Kristen Manto, Mary O’Brien, Prem Kumar Govindappa, John C. Elfar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Peripheral nerve transection is associated with permanent functional deficit even after advanced microsurgical repair. While it is difficult to investigate the reasons of poor functional outcomes of microsurgical repairs in humans, we develo
Externí odkaz:
https://doaj.org/article/b4bbef15c8ee41bd81c3c82b57a1d8cc
Autor:
Francesca Castagnoli, Simon Doran, Jason Lunn, Anna Minchom, Mary O'Brien, Sanjay Popat, Christina Messiou, Dow-Mu Koh
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270950 (2022)
IntroductionThe spleen is a lymphoid organ and we hypothesize that clinical benefit to immunotherapy may present with an increase in splenic volume during treatment. The purpose of this study was to investigate whether changes in splenic volume could
Externí odkaz:
https://doaj.org/article/f28951bef0a44a66b0c982e9b5ad8f8f
Autor:
Sebastian Curcean, M.B.B.S., Lin Cheng, PhD, Simona Picchia, MD, Nina Tunariu, MD, David Collins, PhD, Matthew Blackledge, PhD, Sanjay Popat, MD, Mary O’Brien, MD, Anna Minchom, MD, Martin O. Leach, PhD, Dow-Mu Koh, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 12, Pp 100253- (2021)
Introduction: We compared the magnetic resonance imaging total tumor volume (TTV) and median apparent diffusion coefficient (ADC) of malignant pleural mesothelioma (MPM) before and at 4 weeks after chemotherapy, to evaluate whether these are potentia
Externí odkaz:
https://doaj.org/article/572e9a8380774a418ac096766e983c19
Autor:
Sumeet Hindocha, Des Campbell, Merina Ahmed, Kyriaki Giorgakoudi, Bhupinder Sharma, Nadia Yousaf, Philip Molyneaux, Benjamin Hunter, Hardeep Kalsi, Wanyuan Cui, Michael Davidson, Jaishree Bhosle, Anna Minchom, Imogen Locke, Fiona McDonald, Mary O'Brien, Sanjay Popat, Richard W. Lee
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Pneumonitis is a well-described, potentially life-threatening adverse effect of immune checkpoint inhibitors (ICI) and thoracic radiotherapy. It can require additional investigations, treatment, and interruption of cancer therapy. It is important for
Externí odkaz:
https://doaj.org/article/d7fc4751a1704cf7bbb0ec2d47b86ad1
Autor:
Katherine Knighting, Gerlinde Pilkington, Jane Noyes, Brenda Roe, Michelle Maden, Lucy Bray, Barbara Jack, Mary O’Brien, Julia Downing, Céu Mateus, Sally Spencer
Publikováno v:
Health Services and Delivery Research, Vol 9, Iss 6 (2021)
Background: The number of young adults with complex health-care needs due to life-limiting conditions/complex physical disability has risen significantly over the last 15 years, as more children now survive into adulthood. The transition from childre
Externí odkaz:
https://doaj.org/article/b2aa3b85899e4566890921a57b3efb8a
Autor:
Liz Darlison, Apostolos Nakas, Wendy Underwood, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Introduction Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. As the median survival for patients with mesothelioma is 12.1 months, surgery is an important
Externí odkaz:
https://doaj.org/article/32fc85f80c044e6eb4476952c3c0a85c
Mobilising knowledge on newcomers: Engaging key stakeholders to establish a research hub for Alberta
Publikováno v:
Gateways, Vol 13, Iss 1 (2020)
As immigration to Canada increases, so, too, do the complexities associated with serving various groups of newcomers, including immigrants, refugees, temporary foreign workers and international students. A range of stakeholder groups, such as grassro
Externí odkaz:
https://doaj.org/article/f5ccdb1608714ec7aa2bdbca9c8fbcb5