Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mary Ni Lochlainn"'
Autor:
Mary Ni Lochlainn, Ruth C. E. Bowyer, Janne Marie Moll, María Paz García, Samuel Wadge, Andrei-Florin Baleanu, Ayrun Nessa, Alyce Sheedy, Gulsah Akdag, Deborah Hart, Giulia Raffaele, Paul T. Seed, Caroline Murphy, Stephen D. R. Harridge, Ailsa A. Welch, Carolyn Greig, Kevin Whelan, Claire J. Steves
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Studies suggest that inducing gut microbiota changes may alter both muscle physiology and cognitive behaviour. Gut microbiota may play a role in both anabolic resistance of older muscle, and cognition. In this placebo controlled double blind
Externí odkaz:
https://doaj.org/article/156917d0bdb64152b02a4de514844a81
Autor:
Mary Ni Lochlainn, Ayrun Nessa, Alyce Sheedy, Rachel Horsfall, María Paz García, Deborah Hart, Gulsah Akdag, Darioush Yarand, Samuel Wadge, Andrei-Florin Baleanu, Kevin Whelan, Claire Steves
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Loss of skeletal muscle mass and strength occurs with increasing age and is associated with loss of function, disability, and the development of sarcopenia and frailty. Dietary protein is essential for skeletal muscle function, bu
Externí odkaz:
https://doaj.org/article/728ce29a7eb54069b8fd7586615c0b07
Autor:
Natalie J. Cox, Ruth C.E. Bowyer, Mary Ni Lochlainn, Philippa M. Wells, Helen C. Roberts, Claire J. Steves
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 2, Pp 368-377 (2021)
Abstract Background Anorexia of ageing is common and important in the development of sarcopenia in older individuals. Links have been proposed between the gut microbiota and sarcopenia. Disordered gut function is also recognized in anorexia of ageing
Externí odkaz:
https://doaj.org/article/3af6faac2811423aab8cacc1ef9e9a36
Autor:
Marc F. Österdahl, Karla A. Lee, Mary Ni Lochlainn, Stuart Wilson, Sam Douthwaite, Rachel Horsfall, Alyce Sheedy, Simon D. Goldenberg, Christopher J. Stanley, Tim D. Spector, Claire J. Steves
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT
Externí odkaz:
https://doaj.org/article/3560d14154544216b8bb1e295d7fb5e5
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Aging is associated with a decline in skeletal muscle mass and function—termed sarcopenia—as mediated, in part, by muscle anabolic resistance. This metabolic phenomenon describes the impaired response of muscle protein synthesis (MPS) to the prov
Externí odkaz:
https://doaj.org/article/bf635b9c06214157a4cc6eb0830a59cd
Autor:
Qurrat Ul Ain, Lindsay Jones, Swetha Byravan, Joanne Taylor, Carly Welch, Lauren McCluskey, Fiona Herbert, Hussun-Ara Shah, Sarah Richardson, Thomas A Jackson, Gerry McGonigal, Benjamin Jelley, Jane Masoli, Christopher Miller, Daisy Wilson, Elizabeth Lonsdale-Eccles, Abigail Wrathall, Aidan Ryan, Al Wakkass Mahmood, Alexander Harbinson, Alice Wheeler, Amr Bazaraa, Amy Walter, Anekea Ross, Anna Reay, Chenxian Wu, Chioma Iwu, Dhruv Sarma, Elisabeth Hunter, Elizabeth J Ellis, Emily McNicholas, Fiona E Macdonald, Hannah J Robinson, Hannah Watson, Ijeoma T Obi, Imola Bargaoanu, James E Lucocq, Jane Giddings, Jenni Burton, Jodie Crofts, John Headlam, Kelli Torsney, Kumudhini Giridharan, Lahiru Satharasinghe, Laura J Beeley, Liji Ng, Mary Ni Lochlainn, Michael SJ Wilson, Minal D Patel, Mustafa Alsahab, Nader Nashed, Natalie Cox, Oliver Todd, Olivia Handley, Olugbenro Akintade, Philip Nwabufor, Philippa K Traill, Phillipa Adams, Rinata Farah, Robert Grange, Roisin Healy, Ruth Willott, Sarah Jagdeo, Shonit Nagumantry, Simon M Stapley, Sophie J Irwin, Sophie Wright, Srividya Sundara, Tarunya Vedutla, Thomas Arkle, Thyn Thyn, Vee-Han Lim, Victoria Gaunt, Yathu Matheswaran, Zeinab Majid
Publikováno v:
BMJ Open, Vol 11, Iss 5 (2021)
Objectives This study sets out to ascertain if recognition of delirium impacts on patient outcomes.Design Retrospective cohort study.Setting Unscheduled admissions to acute care trust/secondary care UK hospitals.Participants Six hundred and fifty-six
Externí odkaz:
https://doaj.org/article/6caf786386fe48898c2b0b2d44e0ac5e
Autor:
Ricardo Costeira, Karla A Lee, Benjamin Murray, Colette Christiansen, Juan Castillo-Fernandez, Mary Ni Lochlainn, Joan Capdevila Pujol, Heather Macfarlane, Louise C Kenny, Iain Buchan, Jonathan Wolf, Janice Rymer, Sebastien Ourselin, Claire J Steves, Timothy D Spector, Louise R Newson, Jordana T Bell
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257051 (2021)
It has been widely observed that adult men of all ages are at higher risk of developing serious complications from COVID-19 when compared with women. This study aimed to investigate the association of COVID-19 positivity and severity with estrogen ex
Externí odkaz:
https://doaj.org/article/80044696924c4141b3a6844546d1683d
Autor:
Mary Ni Lochlainn, Natalie J. Cox, Thomas Wilson, Richard P. G. Hayhoe, Sheena E. Ramsay, Antoneta Granic, Masoud Isanejad, Helen C. Roberts, Daisy Wilson, Carly Welch, Christopher Hurst, Janice L. Atkins, Nuno Mendonça, Katy Horner, Esme R. Tuttiett, Yvie Morgan, Phil Heslop, Elizabeth A. Williams, Claire J. Steves, Carolyn Greig, John Draper, Clare A. Corish, Ailsa Welch, Miles D. Witham, Avan A. Sayer, Sian Robinson
Publikováno v:
Nutrients, Vol 13, Iss 7, p 2349 (2021)
Frailty is a syndrome of growing importance given the global ageing population. While frailty is a multifactorial process, poor nutritional status is considered a key contributor to its pathophysiology. As nutrition is a modifiable risk factor for fr
Externí odkaz:
https://doaj.org/article/3ecf2c80dba145ea8f253841d5b2b347
Autor:
Ruth C. E. Bowyer, Matthew A. Jackson, Caroline I. Le Roy, Mary Ni Lochlainn, Tim D. Spector, Jennifer B. Dowd, Claire J. Steves
Publikováno v:
Microorganisms, Vol 7, Iss 1, p 17 (2019)
Socioeconomic inequalities in health and mortality are well established, but the biological mechanisms underlying these associations are less understood. In parallel, the gut microbiome is emerging as a potentially important determinant of human heal
Externí odkaz:
https://doaj.org/article/4b0d553e92194cdeb54941ddefb2abce
Publikováno v:
Nutrients, Vol 10, Iss 7, p 929 (2018)
Muscle mass, strength, and physical function are known to decline with age. This is associated with the development of geriatric syndromes including sarcopenia and frailty. Dietary protein is essential for skeletal muscle function. Resistance exercis
Externí odkaz:
https://doaj.org/article/2a62f2c895e041739dd2b555edb57771