Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mary N. Berkaw"'
Publikováno v:
Molecular & Cellular Proteomics. 8:2733-2745
Insulin receptor substrate-1 (IRS-1) is a highly phosphorylated adaptor protein critical to insulin and IGF-1 receptor signaling. Ser/Thr kinases impact the metabolic and mitogenic effects elicited by insulin and IGF-1 through feedback and feed forwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177b60a06eb879e64e9fdd61648c418b
https://doi.org/10.1074/mcp.m900207-mcp200
https://doi.org/10.1074/mcp.m900207-mcp200
Autor:
Lauren E. Ball, Louis M. Luttrell, Alexis K. Nagel, Jennifer R. Bethard, Grace R. Williams, Mary N. Berkaw
The type 1 parathyroid hormone receptor (PTH1R) is a key regulator of calcium homeostasis and bone turnover. Here, we employed SILAC-based quantitative mass spectrometry combined with bioinformatic pathways analysis to examine global changes in prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985ddb0f4b86c363aa19a8ad72dbe96f
https://europepmc.org/articles/PMC4696908/
https://europepmc.org/articles/PMC4696908/
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ef4388639d4e2f90b0726dcab6ba3e
https://doi.org/10.1096/fasebj.29.1_supplement.728.46
https://doi.org/10.1096/fasebj.29.1_supplement.728.46
Publikováno v:
The FASEB Journal. 29
Posttranslational modifications of IRS1 mediate and modulate the pleiotropic effects elicited by insulin. O-GlcNAc modification of IRS1 correlates with attenuated insulin signaling. We identified O...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef8099ea60e5b0409b60d19456ce7a3
https://doi.org/10.1096/fasebj.29.1_supplement.728.47
https://doi.org/10.1096/fasebj.29.1_supplement.728.47
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 291:E1274-E1280
Tribbles 3 (TRB3) is a recently recognized atypical inactive kinase that negatively regulates Akt activity in hepatocytes, resulting in insulin resistance. Recent reports link TRB3 to nutrient sensing and regulation of cell survival under stressful c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949dd5221c362a308932bb25368bed2a
https://doi.org/10.1152/ajpendo.00117.2006
https://doi.org/10.1152/ajpendo.00117.2006
Publikováno v:
Molecularcellular proteomics : MCP. 12(4)
The nutrient-responsive β-O-linked N-acetylglucosamine (O-GlcNAc) modification of critical effector proteins modulates signaling and transcriptional pathways contributing to cellular development and survival. An elevation in global protein O-GlcNAc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a093af90568c66bf3c955590f869ef
https://pubmed.ncbi.nlm.nih.gov/23443134
https://pubmed.ncbi.nlm.nih.gov/23443134
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e7dbef9ae08c83e93fe820a56ac0531
https://doi.org/10.1096/fasebj.23.1_supplement.878.7
https://doi.org/10.1096/fasebj.23.1_supplement.878.7
Autor:
Mary N. Berkaw, Philippe Arnaud, Phillip A.M. Werner, Catherine Lofton-Day, Francis J. Grant, Joseph R. Day, Patrick J. O'Hara
Publikováno v:
International journal of clinicallaboratory research. 21(3)
Apolipoprotein H, also known as beta-2-glycoprotein I, was purified from human serum, and antiserum produced to denatured apolipoprotein H detected a cDNA clone from a lambda gt11 library derived from human liver. This cDNA coded for the complete seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70361c2ee597a8faf0805eef3d67e2bb
https://pubmed.ncbi.nlm.nih.gov/1339416
https://pubmed.ncbi.nlm.nih.gov/1339416
Autor:
Donna Wilks, Mary N. Berkaw, G. H. Cooney, Maria G. Buse, Lauren E. Ball, N. B. Ruderman, Elaine Preston, A. Saha, Edward W. Kraegen, B. McHenry
Publikováno v:
Journal of Investigative Medicine. 53:S321.5-S321
Increased flux through the hexosamine biosynthetic pathway (HBP) has been proposed as one mechanism by which hyperglycemia induces insulin resistance and complications associated with diabetes. Excess glucose entering the HBP is converted to UDP-GlcN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ecc52e8e567857bd65f487ef1c431d
https://doi.org/10.2310/6650.2005.00006.383
https://doi.org/10.2310/6650.2005.00006.383
Autor:
Gregory B. Wilson, H. Hugh Fudenberg, Blenda P. Garner, Mary N. Berkaw, Haldor T. Jonsson, Perry V. Halushka, Robert E. Powers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46171179d7186b4d0100ef44b9d0a4d1
https://doi.org/10.1016/b978-0-12-406060-9.50021-6
https://doi.org/10.1016/b978-0-12-406060-9.50021-6