Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mary Mulkins"'
Autor:
Tara Mirzadegan, Frank Diehl, Bettina Ebi, Sunil Bhakta, Irene Polsky, Deborah McCarley, Mary Mulkins, Gabe S. Weatherhead, Jean-Marc Lapierre, John Dankwardt, David Morgans, Robert Wilhelm, Kurt Jarnagin
Publikováno v:
Journal of Biological Chemistry. 275:25562-25571
Monocyte chemoattracant-1 (MCP-1) stimulates leukocyte chemotaxis to inflammatory sites, such as rheumatoid arthritis, atherosclerosis, and asthma, by use of the MCP-1 receptor, CCR2, a member of the G-protein-coupled seven-transmembrane receptor sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18289e24da7320fd7e0390483ec5e81b
https://doi.org/10.1074/jbc.m000692200
https://doi.org/10.1074/jbc.m000692200
Autor:
Sunil Bhakta, Kurt Jarnagin, Alan Kosaka, Tracy M. Handel, Chad D. Paavola, Adam Bloom, Dorit Grunberger, Frank Diehl, Stefan Hemmerich, Irene Polsky, Ann Ping-Tsou,‡,⊥, Richard Freedman, Debbie McCarley, Belinda Wong, Mary Mulkins
Publikováno v:
Biochemistry. 38:16167-16177
The CC chemokine, monocyte chemotactic protein, 1 (MCP-1) functions as a major chemoattractant for T-cells and monocytes by interacting with the seven-transmembrane G protein-coupled receptor CCR2. To identify which residues of MCP-1 contribute to si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efb57491a630aa6a905a3bf0f80cd7f
https://doi.org/10.1021/bi9912239
https://doi.org/10.1021/bi9912239
Autor:
Mary Mulkins, Kelly Thompson, Joe H. B. Pease, Laura S. Mizoue, Tracy M. Handel, Tara Mirzadegan, Kurt Jarnagin, John L. Krstenansky, Stefan Hemmerich, Irene Polsky, Debbie McCarley, Chad D. Paavola, Dorit Grunberger, Sunil Bhakta, Richard Freedman, Belinda Wong, Adam Bloom, Simon Ming-Yuen Lee
Publikováno v:
Biochemistry. 38:13013-13025
The CC chemokine, MCP-1, has been identified as a major chemoattractant for T cells and monocytes, and plays a significant role in the pathology of inflammatory diseases. To identify the regions of MCP-1 that contact its receptor, CCR2, we substitute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05bd8ffc86bbe101f214b0e6f15807b
https://doi.org/10.1021/bi991029m
https://doi.org/10.1021/bi991029m
Autor:
Chinh Bach, Mary Mulkins, Patti Zuppan, Rena Obernolte, Sunil Bhakta, Earl R. Shelton, Robert A Alvarez, Kurt Jarnagin
Publikováno v:
Gene. 129:239-247
Five protein families are needed to encompass the diversity of cyclic-AMP (cAMP) phosphodiesterases (PDE). Family IV PDEs (PDE IV) specifically hydrolyze cAMP with a low Km, and are selectively inhibited by rolipram (Rp) and related drugs. Cloned cDN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4be861af94237c5fe72eac7f2b8603
https://doi.org/10.1016/0378-1119(93)90274-7
https://doi.org/10.1016/0378-1119(93)90274-7
Autor:
Pamela Volkel, Yi-Zheng Xu, Martin Huber, Teresa Biegel, Chakkodabylu S. Ramesha, Simon W. Lee, Marie Dinh, Liliana E. Scarafia, Jim W. Barnett, Qing-Fen Gan, Amy Y. Mak, Stacie A. Dalrymple, On-Yee So, James Patrick Dunn, Mary Mulkins, David C. Swinney, Ina Lee
Publikováno v:
The Journal of biological chemistry. 277(26)
A small molecule inhibitor of NF-kappaB-dependent cytokine expression was discovered that blocked tumor necrosis factor (TNF) alpha-induced IkappaB(alpha) degradation in MM6 cells but not the degradation of beta-catenin in Jurkat cells. Ro106-9920 bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa26b171203043d8e1aa00e897eed2ae
https://pubmed.ncbi.nlm.nih.gov/11950839
https://pubmed.ncbi.nlm.nih.gov/11950839
Autor:
Mary Mulkins, Stefan Hemmerich, Kurt Jarnagin, Richard Freedman, Belinda Wong, Tracy M. Handel, Sunhil Bhakta, Ludwig Wiesent, Chad D. Paavola, Dorit Grunberger, Irene Polsky, Adam Bloom, Debbie McCarley
Publikováno v:
The Journal of biological chemistry. 273(50)
To address the role of dimerization in the function of the monocyte chemoattractant protein-1, MCP-1, we mutated residues that comprise the core of the dimerization interface and characterized the ability of these mutants to dimerize and to bind and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b782fdfd72a0b4ae6caee788b7c66d
https://pubmed.ncbi.nlm.nih.gov/9837883
https://pubmed.ncbi.nlm.nih.gov/9837883